Issue 5/2010
Content (22 Articles)
Extracellular fluid concentrations of cisplatin, carboplatin, and oxaliplatin in brain, muscle, and blood measured using microdialysis in nonhuman primates
Shana Jacobs, Cynthia L. McCully, Robert F. Murphy, John Bacher, Frank M. Balis, Elizabeth Fox
Epidermal growth factor receptor (EGFR) mRNA levels and protein expression levels in primary colorectal cancer and corresponding liver metastases
Hidekazu Kuramochi, Kazuhiko Hayashi, Go Nakajima, Hirotaka Kamikozuru, Masakazu Yamamoto, Kathleen D. Danenberg, Peter V. Danenberg
A phase I trial of SJG-136 (NSC#694501) in advanced solid tumors
Yelena Y. Janjigian, Wooin Lee, Mark G. Kris, Vincent A. Miller, Lee M. Krug, Christopher G. Azzoli, Emir Senturk, M. Wade Calcutt, Naiyer A. Rizvi
Limited inter-occasion variability in relation to inter-individual variability in chemotherapy-induced myelosuppression
Emma K. Hansson, Johan E. Wallin, Henrik Lindman, Marie Sandström, Mats O. Karlsson, Lena E. Friberg
Cetuximab-based therapy versus non-cetuximab therapy for advanced cancer: a meta-analysis of 17 randomized controlled trials
Lidan Liu, Yunfei Cao, Aihua Tan, Cun Liao, Feng Gao
A phase I dose escalation study of a pharmacobiologically based scheduling of capecitabine and mitomycin C in patients with gastrointestinal malignancies
Tanios Bekaii-Saab, Marisa Hill, Angela Campbell, Kavitha Kosuri, James Thomas, Miguel Villalona-Calero
A phase IB dose-finding trial of liposomal doxorubicin in combination with capecitabine in patients with pretreated metastatic breast cancer
Andrea Rocca, Roberta Maltoni, Alessandro Passardi, Ilaria Massa, Michele Aquilina, Ruggero Ridolfi, Toni Ibrahim, Lorenzo Cecconetto, Samanta Sarti, Elisabetta Pietri, Oriana Nanni, Dino Amadori
Induction of necrosis and cell cycle arrest in murine cancer cell lines by Melaleuca alternifolia (tea tree) oil and terpinen-4-ol
S. J. Greay, D. J. Ireland, H. T. Kissick, A. Levy, M. W. Beilharz, T. V. Riley, C. F. Carson
Expression of an activated mammalian target of rapamycin (mTOR) in gastroenteropancreatic neuroendocrine tumors
Takashi Shida, Takashi Kishimoto, Mitsuko Furuya, Takashi Nikaido, Keiji Koda, Shigetsugu Takano, Fumio Kimura, Hiroaki Shimizu, Hiroyuki Yoshidome, Masayuki Ohtsuka, Tohru Tanizawa, Yukio Nakatani, Masaru Miyazaki
Artesunate induces oncosis-like cell death in vitro and has antitumor activity against pancreatic cancer xenografts in vivo
Ji-Hui Du, Hou-De Zhang, Zhen-Jian Ma, Kun-Mei Ji
Celecoxib inhibits MDR1 expression through COX-2-dependent mechanism in human hepatocellular carcinoma (HepG2) cell line
Karnati R. Roy, Gorla V. Reddy, Leela Maitreyi, Smita Agarwal, Chandrani Achari, Shireen Vali, Pallu Reddanna
Optimization of the non-invasive 13C-sucrose breath test in a rat model of methotrexate-induced mucositis
K. L. Tooley, G. S. Howarth, K. A. Lymn, R. N. Butler
Preclinical efficacy studies of a novel nanoparticle-based formulation of paclitaxel that out-performs Abraxane
Zhongling Feng, Gang Zhao, Lei Yu, David Gough, Stephen B. Howell
Antimetastatic, antineoplastic, and toxic effects of 4-hydroxycoumarin in a preclinical mouse melanoma model
Nohemí Salinas-Jazmín, Marisol de la Fuente, Ruth Jaimez, Mayra Pérez-Tapia, Armando Pérez-Torres, Marco A. Velasco-Velázquez
Mechanistic study of BNP7787-mediated cisplatin nephroprotection: modulation of gamma-glutamyl transpeptidase
Frederick H. Hausheer, Dakshine Shanmugarajah, Betsy D. Leverett, Xinghai Chen, Quili Huang, Harry Kochat, Pavankumar N. Petluru, Aulma R. Parker
Co-administration of irinotecan decreases the plasma concentration of an active metabolite of amrubicin, amrubicinol in rats
Yukiko Maeda, Akinobu Hamada, Emiko Sanematsu, Ji-ichro Sasaki, Koji Yokoo, Asumi Hira, Hideyuki Saito
Phase II study of motesanib in Japanese patients with advanced gastrointestinal stromal tumors with prior exposure to imatinib mesylate
Akira Sawaki, Yasuhide Yamada, Yoshito Komatsu, Tatsuo Kanda, Toshihiko Doi, Masato Koseki, Hideo Baba, Yu-Nien Sun, Koji Murakami, Toshirou Nishida
Increased anti-tumour effects of doxorubicin and zoledronic acid in prostate cancer cells in vitro: supporting the benefits of combination therapy
Rhys D. Clyburn, Penny Reid, Catherine A. Evans, Diane V. Lefley, Ingunn Holen
A phase I/II trial of vorinostat in combination with 5-fluorouracil in patients with metastatic colorectal cancer who previously failed 5-FU-based chemotherapy
Peter M. Wilson, Anthony El-Khoueiry, Syma Iqbal, William Fazzone, Melissa J. LaBonte, Susan Groshen, Dongyun Yang, Kathy D. Danenberg, Sarah Cole, Margaret Kornacki, Robert D. Ladner, Heinz-Josef Lenz
DNA damage induced by the anthracycline cosmomycin D in DNA repair-deficient cells
Helotonio Carvalho, Leandro M. Garrido, Renata L. A. Furlan, Gabriel Padilla, Mateus Agnoletto, Temenouga Guecheva, João A. P. Henriques, Jenifer Saffi, Carlos Frederico Martins Menck
In vitro assessment of cytochrome P450 inhibition and induction potential of azacitidine
Yong Chen, Lisa Liu, Eric Laille, Gondi Kumar, Sekhar Surapaneni
Rapid and complete resolution of chemotherapy-induced thrombotic thrombocytopenic purpura/hemolytic uremic syndrome (TTP/HUS) with rituximab
Brett L. Gourley, Hector Mesa, Pankaj Gupta