Issue 4/2007
Content (16 Articles)
Phase I and pharmacologic study of irinotecan and amrubicin in advanced non-small cell lung cancer
Tomoko Yanaihara, Masanori Yokoba, Sayaka Onoda, Michiko Yamamoto, Shinichiro Ryuge, Shintaro Hagiri, Masato Katagiri, Mayuko Wada, Hisashi Mitsufuji, Masaru Kubota, Susumu Arai, Hirosuke Kobayashi, Nobuo Yanase, Tadashi Abe, Noriyuki Masuda
Androgen and c-Kit receptors in desmoplastic small round cell tumors resistant to chemotherapy: novel targets for therapy
Robert L. Fine, Samir S. Shah, Thomas A. Moulton, Ing-Ru Yu, David R. Fogelman, Michael Richardson, Howard A. Burris, Brian L. Samuels, Chatchawin Assanasen, Prakash Gorroochurn, Hanina Hibshoosh, Manuela Orjuela, James Garvin, Frederick D. Goldman, Daniel Dubovsky, David Walterhouse, Gregory Halligan
Fascaplysin, a selective CDK4 inhibitor, exhibit anti-angiogenic activity in vitro and in vivo
Jing Lin, Xiao-Jun Yan, Hai-Min Chen
A phase II study of weekly irinotecan as first-line therapy for patients with metastatic pancreatic cancer
Hideki Ueno, Takuji Okusaka, Akihiro Funakoshi, Hiroshi Ishii, Kenji Yamao, Osamu Ishikawa, Shinichi Ohkawa, Soh Saitoh
Effects of mycophenolate mofetil on cisplatin-induced renal dysfunction in rats
Sherif Y. Saad, Maha M. Arafah, Tawfeeg A. Najjar
Plasma and cerebrospinal fluid pharmacokinetics of pemetrexed after intravenous administration in non-human primates
Stacie L. Stapleton, Joel M. Reid, Patrick A. Thompson, Matthew M. Ames, Renee M. McGovern, Leticia McGuffey, Jed Nuchtern, Robert Dauser, Susan M. Blaney
A phase I trial of intermittent high-dose gefitinib and fixed-dose docetaxel in patients with advanced solid tumors
Matthew G. Fury, David B. Solit, Yungpo Bernard Su, Neal Rosen, F. M. Sirotnak, Robert P. Smith, Christopher G. Azzoli, Jorge E. Gomez, Vincent A. Miller, Mark G. Kris, Barbara A. Pizzo, Roxanne Henry, David G. Pfister, Naiyer A. Rizvi
Poly(ethylene oxide)-modified poly(beta-amino ester) nanoparticles as a pH-sensitive system for tumor-targeted delivery of hydrophobic drugs: part 3. Therapeutic efficacy and safety studies in ovarian cancer xenograft model
Harikrishna Devalapally, Dinesh Shenoy, Steven Little, Robert Langer, Mansoor Amiji
Pharmacokinetics of arsenic species in Japanese patients with relapsed or refractory acute promyelocytic leukemia treated with arsenic trioxide
Shinya Fujisawa, Ryuzo Ohno, Kazuyuki Shigeno, Naohi Sahara, Satoki Nakamura, Kensuke Naito, Miki Kobayashi, Kaori Shinjo, Akihiro Takeshita, Yoshinari Suzuki, Hisakuni Hashimoto, Kenji Kinoshita, Masahito Shimoya, Toshikazu Kaise, Kazunori Ohnishi
Glucose uptake inhibitor sensitizes cancer cells to daunorubicin and overcomes drug resistance in hypoxia
Xianhua Cao, Lanyan Fang, Seth Gibbs, Ying Huang, Zunyan Dai, Ping Wen, Xincheng Zheng, Wolfgang Sadee, Duxin Sun
Clinical evaluation of chemosensitivity testing for patients with unresectable non-small cell lung cancer (NSCLC) using collagen gel droplet embedded culture drug sensitivity test (CD-DST)
Masafumi Kawamura, Masatoshi Gika, Tomohiro Abiko, Yoshimasa Inoue, Takahiko Oyama, Yotaro Izumi, Hisayuki Kobayashi, Koichi Kobayashi
Additive antitumor effect of concurrent treatment of 4-hydroxy tamoxifen with 5-fluorouracil but not with doxorubicin in estrogen receptor-positive breast cancer cells
Junichi Kurebayashi, Mamoru Nukatsuka, Hideki Nagase, Tsunehisa Nomura, Mai Hirono, Yutaka Yamamoto, Yoshikazu Sugimoto, Toshinori Oka, Hiroshi Sonoo
Adaphostin cytoxicity in glioblastoma cells is ROS-dependent and is accompanied by upregulation of heme oxygenase-1
Jason Long, Tejas Manchandia, Kechen Ban, Shan Gao, Claudia Miller, Joya Chandra
In vitro and in vivo metabolism of paclitaxel poliglumex: identification of metabolites and active proteases
Scott A. Shaffer, Cassie Baker-Lee, Jacob Kennedy, Man Shun Lai, Peter de Vries, Kent Buhler, Jack W. Singer
A phase I study of oxaliplatin in combination with gemcitabine: correlation of clinical outcome with gene expression
Stephen Shibata, Warren Chow, Paul Frankel, Agnes Juhasz, Lucille Leong, Dean Lim, Kim Margolin, Robert Morgan, Edward Newman, George Somlo, Yun Yen, Timothy Synold, David Gandara, Heinz-Josef Lenz, James Doroshow
Pharmacodynamic effects of high dose lovastatin in subjects with advanced malignancies
Sarah A. Holstein, Howard R. Knapp, Gerald H. Clamon, Daryl J. Murry, Raymond J. Hohl