Issue 2/2013
Content (24 Articles)
CYP2D6 polymorphisms influence tamoxifen treatment outcomes in breast cancer patients: a meta-analysis
Zhiyu Zeng, Yanqiong Liu, Zhiming Liu, Jianpeng You, Zhiping Chen, Jian Wang, Qiliu Peng, Li Xie, Ruolin Li, Shan Li, Xue Qin
Association between GSTP1 Ile105Val polymorphism and oxaliplatin-induced neuropathy: a systematic review and meta-analysis
Zhi Peng, Qianqian Wang, Jing Gao, Zhaoning Ji, Jiajia Yuan, Ye Tian, Lin Shen
Polymorphisms in ERCC1 C8092A predict progression-free survival in metastatic/recurrent nasopharyngeal carcinoma treated with cisplatin-based chemotherapy
Cui Chen, Fenghua Wang, Zhiqiang Wang, Cong Li, Huiyan Luo, Ying Liang, Xin An, Jianyong Shao, Yuhong Li
Multicenter phase II study of capecitabine combined with nedaplatin for recurrent and metastatic nasopharyngeal carcinoma patients after failure of cisplatin-based chemotherapy
Pei-Jian Peng, Xue-Qing Ou, Zhi-Bin Chen, Hai Liao, Yu-Long Peng, Si-Yang Wang, Hong-Yu Zhang, Zhong Lin
Synergistic interactions between camptothecin and EGFR or RAC1 inhibitors and between imatinib and Notch signaling or RAC1 inhibitors in glioblastoma cell lines
Linda Sooman, Simon Ekman, Claes Andersson, Hanna Göransson Kultima, Anders Isaksson, Fredrik Johansson, Michael Bergqvist, Erik Blomquist, Johan Lennartsson, Joachim Gullbo
Significant increase in hEGF uptake is correlated with formation of EGFR dimers induced by the EGFR tyrosine kinase inhibitor gefitinib
Peng He, Gang Li
The pharmacokinetics of letrozole in brain and brain tumor in rats with orthotopically implanted C6 glioma, assessed using intracerebral microdialysis
Nimita Dave, Gary A. Gudelsky, Pankaj B. Desai
Hepatic activation of irinotecan predicts tumour response in patients with colorectal liver metastases treated with DEBIRI: exploratory findings from a phase II study
R. P. Jones, P. Sutton, R. M. D. Greensmith, A. Santoyo-Castelazo, D. F. Carr, R. Jenkins, C. Rowe, J. Hamlett, B. K. Park, M. Terlizzo, E. O’Grady, P. Ghaneh, S. W. Fenwick, H. Z. Malik, G. J. Poston, N. R. Kitteringham
Between-course targeting of methotrexate exposure using pharmacokinetically guided dosage adjustments
Jennifer L. Pauley, John C. Panetta, Kristine R. Crews, Deqing Pei, Cheng Cheng, John McCormick, Scott C. Howard, John T. Sandlund, Sima Jeha, Raul Ribeiro, Jeffrey Rubnitz, Ching-Hon Pui, William E. Evans, Mary V. Relling
A phase I, open-label, mass balance study of [14C] dacomitinib (PF-00299804) in healthy male volunteers
Carlo L. Bello, Evan Smith, Ana Ruiz-Garcia, Grace Ni, Christine Alvey, Cho-Ming Loi
Safety, tolerability, pharmacokinetics, and pharmacodynamics of a long-acting release (LAR) formulation of pasireotide (SOM230) in patients with gastroenteropancreatic neuroendocrine tumors: results from a randomized, multicenter, open-label, phase I study
Edward M. Wolin, Ke Hu, Gareth Hughes, Emmanuel Bouillaud, Vanessa Giannone, Karina Hermosillo Resendiz
Epidermal growth factor receptor (EGFR) and KRAS mutations during chemotherapy plus anti-EGFR monoclonal antibody treatment in metastatic colorectal cancer
David Tougeron, Ulrich Cortes, Aurélie Ferru, Claire Villalva, Christine Silvain, Jean Marc Tourani, Pierre Levillain, Lucie Karayan-Tapon
Death receptor 5 agonistic antibody PRO95780: preclinical pharmacokinetics and concentration–effect relationship support clinical dose and regimen selection
Hong Xiang, Arthur E. Reyes II, Steve Eppler, Sean Kelley, Lisa A. Damico-Beyer
Validation of tumour models for use in anticancer nanomedicine evaluation: the EPR effect and cathepsin B-mediated drug release rate
Ruth Duncan, Yee-Nee Sat-Klopsch, Angelika M. Burger, Michael C. Bibby, Heinz H. Fiebig, Edward A. Sausville
Phase II study of single agent oral vinorelbine as first-line treatment in patients with HER-2 negative metastatic breast cancer
Maged Mansour, Cynthia Mourad
A high serum level of M65 is associated with tumour aggressiveness and an unfavourable prognosis for epithelial ovarian cancer
Ibrahim Yildiz, Faruk Tas, Leyla Kilic, Fatma Sen, Pinar Saip, Yesim Eralp, Serkan Keskin, Senem Karabulut, Rumeysa Ciftci, Murat Serilmez, Vildan Yasasever, Adnan Aydiner
Maintenance therapy with pemetrexed versus docetaxel after induction therapy with carboplatin and pemetrexed in chemotherapy-naïve patients with advanced non-squamous non-small-cell lung cancer: a randomized, phase II study
Masato Karayama, Naoki Inui, Shigeki Kuroishi, Koshi Yokomura, Mikio Toyoshima, Toshihiro Shirai, Masafumi Masuda, Takashi Yamada, Kazumasa Yasuda, Takafumi Suda, Kingo Chida
Risk of hemoptysis in patients with resected squamous cell and other high-risk lung cancers treated with adjuvant bevacizumab
Matthew D. Hellmann, Jamie E. Chaft, Valerie Rusch, Michelle S. Ginsberg, David J. Finley, Mark G. Kris, Katharine A. R. Price, Christopher. G. Azzoli, Matthew G. Fury, Gregory J. Riely, Lee M. Krug, Robert J. Downey, Manjit S. Bains, Camelia S. Sima, Nabil Rizk, William D. Travis, Naiyer A. Rizvi, Paul K. Paik
A multi-institutional phase II trial of hepatic arterial infusion chemotherapy with cisplatin for advanced hepatocellular carcinoma with portal vein tumor thrombosis
Masafumi Ikeda, Takuji Okusaka, Junji Furuse, Shuichi Mitsunaga, Hideki Ueno, Hidekazu Yamaura, Yoshitaka Inaba, Yoshito Takeuchi, Mitsuo Satake, Yasuaki Arai
A predictive pharmacokinetic–pharmacodynamic model of tumor growth kinetics in xenograft mice after administration of anticancer agents given in combination
Nadia Terranova, Massimiliano Germani, Francesca Del Bene, Paolo Magni
DMET™ (Drug-Metabolizing Enzymes and Transporters) microarray analysis of colorectal cancer patients with severe 5-fluorouracil-induced toxicity
Enrica Rumiato, Elisa Boldrin, Alberto Amadori, Daniela Saggioro
Ipilimumab-induced endocrinopathies: when to start corticosteroids (or not)
Salvatore Maria Corsello, Roberto Salvatori, Agnese Barnabei, Liana De Vecchis, Paolo Marchetti, Francesco Torino
Erratum to: Differential toxicity biomarkers for irinotecan- and oxaliplatin- containing chemotherapy in colorectal cancer
Lucía Cortejoso, María I. García, Pilar García-Alfonso, Eva González-Haba, Fernando Escolar, María Sanjurjo, Luis A. Lόpez-Fernández