Issue 2/2009
Content (21 Articles)
cis-3, 4′, 5-Trimethoxy-3′-aminostilbene disrupts tumor vascular perfusion without damaging normal organ perfusion
David Durrant, Frank Corwin, Daniele Simoni, Ming Zhao, Michelle A. Rudek, Fadi N. Salloum, Rakesh C. Kukreja, Panos P. Fatouros, Ray M. Lee
Preclinical efficacy spectrum and pharmacokinetics of ixabepilone
Francis Y. F. Lee, Richard Smykla, Kathy Johnston, Krista Menard, Kelly McGlinchey, Russell W. Peterson, Amy Wiebesiek, Gregory Vite, Craig R. Fairchild, Robert Kramer
Phase I dose-escalating study of 24-h continuous infusion of 5-fluorouracil in combination with weekly docetaxel and cisplatin in patients with advanced gastric cancer
Biyun Wang, Wen Zhang, Xiaonan Hong, Ye Guo, Jin Li
Her2/neu signaling blockade improves tumor oxygenation in a multifactorial fashion in Her2/neu+ tumors
Matthew E. Hardee, Rose J. Eapen, Zahid N. Rabbani, Matthew R. Dreher, Jeffrey Marks, Kimberly L. Blackwell, Mark W. Dewhirst
Population pharmacokinetics of imatinib mesylate and its metabolite in children and young adults
Divya Menon-Andersen, John T. Mondick, Bhuvana Jayaraman, Patrick A. Thompson, Susan M. Blaney, Mark Bernstein, Mason Bond, Martin Champagne, Michael J. Fossler, Jeffrey S. Barrett
Is the pathobiology of chemotherapy-induced alimentary tract mucositis influenced by the type of mucotoxic drug administered?
Richard M. Logan, Andrea M. Stringer, Joanne M. Bowen, Rachel J. Gibson, Stephen T. Sonis, Dorothy M. K. Keefe
Phase I dose escalation study of docetaxel with a fixed dose of S-1 in combination chemotherapy for advanced gastric cancer
Yeul Hong Kim, Hee Yeon Seo, Yoon Tae Jeen, Hoon-Kyo Kim, Byoung Yong Shim, Jinmo Yang
Meta-analysis of pre-operative aromatase inhibitor versus tamoxifen in postmenopausal woman with hormone receptor-positive breast cancer
Jae Hong Seo, Yeul Hong Kim, Jun Suk Kim
Phase I/II trial of combination therapy with S-1 and weekly paclitaxel in patients with unresectable or recurrent gastric cancer
Seisuke Inada, Takashi Tomidokoro, Hiroyuki Fukunari, Tomomi Sato, Toru Hatano, Atsushi Nishimura, Yasuyuki Kawauchi, Keiya Nikkuni, Takeaki Shimizu, Toshiteru Sato, Masahiko Yanagi, Satoru Takahashi, Hideki Yoshida, Minoru Sugita, Tetsuji Hayashi
Central nervous system metastases in a cohort of metastatic breast cancer patients treated with trastuzumab
E. Montagna, G. Cancello, D. D’Agostino, R. Lauria, V. Forestieri, A. Esposito, L. Silvestro, A. Accurso, S. De Placido, M. De Laurentiis
Use of cholesterol-rich nanoparticles that bind to lipoprotein receptors as a vehicle to paclitaxel in the treatment of breast cancer: pharmacokinetics, tumor uptake and a pilot clinical study
Luís A. Pires, Roberto Hegg, Claudete J. Valduga, Sílvia R. Graziani, Débora G. Rodrigues, Raul C. Maranhão
Human concentrative nucleoside transporter 3 is a determinant of fludarabine transportability and cytotoxicity in human renal proximal tubule cell cultures
Adam N. Elwi, Vijaya L. Damaraju, Michelle L. Kuzma, Stephen A. Baldwin, James D. Young, Michael B. Sawyer, Carol E. Cass
NSC606985, a novel camptothecin analog, induces apoptosis and growth arrest in prostate tumor cells
Chen Tan, Li-Qun Cai, Wendy Wu, Yaming Qiao, Julianne Imperato-McGinley, Guo-Qiang Chen, Yuan-Shan Zhu
A phase II study of S-1 in gemcitabine-refractory metastatic pancreatic cancer
Chigusa Morizane, Takuji Okusaka, Junji Furuse, Hiroshi Ishii, Hideki Ueno, Masafumi Ikeda, Kohei Nakachi, Mina Najima, Takashi Ogura, Eiichiro Suzuki
Considerations for intravascular administration of oncolytic herpes virus for the treatment of multiple liver metastases
Naohiro Nomura, Hideki Kasuya, Izuru Watanabe, Toshio Shikano, Takashi Shirota, Makoto Misawa, Hiroyuki Sugimoto, Naohito Kanazumi, Shuji Nomoto, Shin Takeda, Akimasa Nakao
A phase I pharmacokinetic study of hypoxic abdominal stop-flow perfusion with gemcitabine in patients with advanced pancreatic cancer and refractory malignant ascites
Andrea Kuemmerle, Laurent A. Decosterd, Thierry Buclin, Danielle Liénard, Roger Stupp, Pierre-Guy Chassot, François Mosimann, Ferdy Lejeune
Dexrazoxane protects against doxorubicin-induced cardiomyopathy: upregulation of Akt and Erk phosphorylation in a rat model
Ping Xiang, Hai Yan Deng, Karen Li, Guo-Ying Huang, Yuan Chen, Liu Tu, Pak Cheung Ng, Nga Hin Pong, Hailu Zhao, Lei Zhang, Rita Yn Tz Sung
Sodium selenite induces apoptosis by generation of superoxide via the mitochondrial-dependent pathway in human prostate cancer cells
Nong Xiang, Rui Zhao, Weixiong Zhong
A phase II study of pegylated-camptothecin (pegamotecan) in the treatment of locally advanced and metastatic gastric and gastro-oesophageal junction adenocarcinoma
L. C. Scott, J. C. Yao, A. B. Benson III, A. L. Thomas, S. Falk, R. R. Mena, J. Picus, J. Wright, M. F. Mulcahy, J. A. Ajani, T. R. J. Evans
Administration of oxaliplatin to a pregnant woman with rectal cancer
Michael Gensheimer, Catherine A. Jones, Cornelia R. Graves, Nipun B. Merchant, A. Craig Lockhart
Altered cyclophosphamide and thiotepa pharmacokinetics in a patient with moderate renal insufficiency
Corine Ekhart, J. Martijn Kerst, Sjoerd Rodenhuis, Jos H. Beijnen, Alwin D. R. Huitema