Issue 2/2006
Content (17 Articles)
Camptothecin analogs with enhanced activity against human breast cancer cells. I. Correlation of potency with lipophilicity and persistence in the cleavage complex
David J. Adams, Mateus Webba da Silva, James L. Flowers, Glenda Kohlhagen, Yves Pommier, O. Michael. Colvin, Govindarajan Manikumar, Mansukh C. Wani
Camptothecin analogs with enhanced activity against human breast cancer cells. II. Impact of the tumor pH gradient
David J. Adams, Miriam L. Wahl, James L. Flowers, Banalata Sen, Michael Colvin, Mark W. Dewhirst, Govindarajan Manikumar, Mansukh C. Wani
Pharmacodynamic effects of high dose lovastatin in subjects with advanced malignancies
Sarah A. Holstein, Howard R. Knapp, Gerald H. Clamon, Daryl J. Murry, Raymond J. Hohl
4-methylumbelliferone, a hyaluronan synthase suppressor, enhances the anticancer activity of gemcitabine in human pancreatic cancer cells
Hideaki Nakazawa, Shuichi Yoshihara, Daisuke Kudo, Hajime Morohashi, Ikuko Kakizaki, Atsushi Kon, Keiichi Takagaki, Mutsuo Sasaki
Low folate conditions may enhance the interaction of trifluorothymidine with antifolates in colon cancer cells
Olaf H. Temmink, Marco F. M. Hoogeland, Masakazu Fukushima, Godefridus J. Peters
Thiolo-, thiono- and dithiocarbonate and thiocarbamate derivatives of demethylpenclomedine as novel anticancer agents
Robert F. Struck, William R. Waud
Gemcitabine plus celecoxib (GECO) in advanced pancreatic cancer: a phase II trial
Vittorio Ferrari, Francesca Valcamonico, Vito Amoroso, Edda Simoncini, Lucia Vassalli, Patrizia Marpicati, Giovanni Rangoni, Salvatore Grisanti, Guido AM Tiberio, Franco Nodari, Carla Strina, Giovanni Marini
Intravenous busulfan in adults prior to haematopoietic stem cell transplantation: a population pharmacokinetic study
L. Nguyen, F. Leger, S. Lennon, C. Puozzo
Pharmacokinetics, pharmacodynamics and adherence to oral topotecan in myelodysplastic syndromes: a Cancer and Leukemia Group B study
Cheri E. Klein, Helen Kastrissios, Antonius A. Miller, Donna Hollis, Daohai Yu, Gary L. Rosner, David L. Grinblatt, Richard A. Larson, Mark J. Ratain
Combination of topotecan and cisplatin in relapsed patients with small cell lung cancer: a phase II study of the hellenic cooperative oncology group (HeCOG)
Christos Christodoulou, Haralambos P. Kalofonos, Evangelos Briasoulis, Dimitrios Bafaloukos, Thomas Makatsoris, Angelos Koutras, Dimosthenis V. Skarlos, Epaminondas Samantas
Dihydroartemisinin downregulates vascular endothelial growth factor expression and induces apoptosis in chronic myeloid leukemia K562 cells
Jun Lee, Hui-Jun Zhou, Xiu-Hua Wu
Structure-activity study of the interaction of bioreductive benzoquinone alkylating agents with DNA topoisomerase II
Brian B. Hasinoff, Xing Wu, Asher Begleiter, Lynn J. Guziec, Frank Guziec Jr, Angela Giorgianni, Shaohua Yang, Yu Jiang, Jack C. Yalowich
Expression of VDR and CYP24A1 mRNA in human tumors
Mark G. Anderson, Masaki Nakane, Xiaoan Ruan, Paul E. Kroeger, J. Ruth Wu-Wong
Prospective evaluation of carboplatin AUC dosing in patients with a BMI ≥27 or Cachexia
Jon D. Herrington, Hai T. Tran, Mark W. Riggs
Experimental study of the inhibition of human hepatocarcinoma Bel7402 cells by the tripeptide tyroserleutide(YSL)
Rong Lu, Jing Jia, Leyuan Bao, Zheng Fu, Guoli Li, Song Wang, Zhuo Wang, Mengjue Jin, Wenyuan Gao, Zhi Yao
Analysis of cytotoxicities of platinum compounds
Jerry Goodisman, Douglas Hagrman, Kirk A. Tacka, Abdul-Kader Souid
Antiproliferative activity of contragestazol (DL111-IT) in murine and human tumor models in vitro and in vivo
Bo Yang, Qiao-jun He, Dan-yan Zhu, Yi-jia Lou, Rui-ying Fang