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Cancer Chemotherapy and Pharmacology

Issue 1/2015

Content (26 Articles)

Review Article

Endometrial cancer: redefining the molecular-targeted approach

Jesse Lopes da Silva, Eduardo Paulino, Mariane Fontes Dias, Andréia Cristina de Melo

Original Article

A proof of concept trial of the anti-EGFR antibody mixture Sym004 in patients with squamous cell carcinoma of the head and neck

J.-P. Machiels, P. Specenier, J. Krauß, A. Dietz, M.-C. Kaminsky, Y. Lalami, M. Henke, U. Keilholz, R. Knecht, N. J. Skartved, I. D. Horak, P. Pamperin, S. Braun, T. C. Gauler

Original Article

Sandwich-like neoadjuvant therapy with bevacizumab for locally advanced rectal cancer: a phase II trial

Jian Xiao, Zexian Chen, Wenyun Li, Zuli Yang, Yan Huang, Jian Zheng, Yanhong Deng, Lei Wang, Donglin Ren, Junsheng Peng, Ping Lan, Jianping Wang

Original Article

Pilot study of modified FOLFOX6 adjuvant chemotherapy for high-risk rectal cancer treated with neoadjuvant chemoradiotherapy

Soo Jung Lee, Byung Woog Kang, Yee Soo Chae, Seung Hyun Cho, Hye Jin Kim, Su Yeon Park, Jun Seok Park, Gyu Seog Choi, Jong Gwang Kim

Open Access Original Article

Direct and indirect targeting of MYC to treat acute myeloid leukemia

Sam Brondfield, Sushma Umesh, Alexandra Corella, Johannes Zuber, Amy R. Rappaport, Coline Gaillard, Scott W. Lowe, Andrei Goga, Scott C. Kogan

Original Article

Influence of metastatic disease on the usefulness of uracil pharmacokinetics as a screening tool for DPD activity in colorectal cancer patients

Maurice C. van Staveren, Frans Opdam, Henk-Jan Guchelaar, André B. P. van Kuilenburg, Jan Gerard Maring, Hans Gelderblom

Original Article

Extension of the Calvert formula to patients with severe renal insufficiency

Tomoyo Oguri, Tomoya Shimokata, Isao Ito, Yoshinari Yasuda, Naoto Sassa, Masami Nishiyama, Akinobu Hamada, Yoshinori Hasegawa, Yuichi Ando

Original Article

Phase II trial of everolimus in patients with refractory metastatic adenocarcinoma of the esophagus, gastroesophageal junction and stomach: possible role for predictive biomarkers

Zev A. Wainberg, Heloisa P. Soares, Ravi Patel, Brian DiCarlo, David J. Park, Andre Liem, He-jing Wang, Lisa Yonemoto, Diego Martinez, Isett Laux, Meghan Brennan, J. Randolph Hecht

Original Article

Second-line docetaxel for patients with platinum-refractory advanced non-small cell lung cancer and interstitial pneumonia

Naohiro Watanabe, Seiji Niho, Keisuke Kirita, Shigeki Umemura, Shingo Matsumoto, Kiyotaka Yoh, Hironobu Ohmatsu, Koichi Goto

Open Access Original Article

Initial safety report on the tolerability of modified FOLFOX6 as adjuvant therapy in patients with curatively resected stage II or III colon cancer (JFMC41-1001-C2: JOIN trial)

Masahito Kotaka, Takayuki Yoshino, Koji Oba, Katsunori Shinozaki, Tetsuo Touyama, Dai Manaka, Takanori Matsui, Kiyoshi Ishigure, Junichi Hasegawa, Keiji Inoue, Koichi Goto, Junichi Sakamoto, Shigetoyo Saji, Atsushi Ohtsu, Toshiaki Watanabe

Original Article

Association of fludarabine pharmacokinetic/dynamic biomarkers with donor chimerism in nonmyeloablative HCT recipients

Jeannine S. McCune, Donald E. Mager, Meagan J. Bemer, Brenda M. Sandmaier, Barry E. Storer, Shelly Heimfeld

Open Access Original Article

Double-blind, placebo-controlled, randomized phase II study of TJ-14 (Hangeshashinto) for infusional fluorinated-pyrimidine-based colorectal cancer chemotherapy-induced oral mucositis

Chu Matsuda, Yoshinori Munemoto, Hideyuki Mishima, Naoki Nagata, Mitsuru Oshiro, Masato Kataoka, Junichi Sakamoto, Toru Aoyama, Satoshi Morita, Toru Kono

Original Article

Development of a new equation to estimate creatinine clearance in cancer patients

Michael P. Chu, Larissa McCaw, Cynthia Stretch, Charles Butts, John Hanson, Michelle Kuzma, Vijaya L. Damaraju, Vickie E. Baracos, Michael B. Sawyer

Original Article

Comparison of the pharmacokinetics of erlotinib administered in complete fasting and 2 h after a meal in patients with lung cancer

Yuki Katsuya, Yutaka Fujiwara, Kuniko Sunami, Hirofumi Utsumi, Yasushi Goto, Shintaro Kanda, Hidehito Horinouchi, Hiroshi Nokihara, Noboru Yamamoto, Yuki Takashima, Satoko Osawa, Yuichiro Ohe, Tomohide Tamura, Akinobu Hamada

Original Article

Safety, tolerability, and efficacy of oxaliplatin-based adjuvant chemotherapy after curative resection of hepatic or extrahepatic metastases of Stage IV colorectal cancer

Izuma Nakayama, Mitsukuni Suenaga, Takeru Wakatsuki, Takashi Ichimura, Masato Ozaka, Daisuke Takahari, Eiji Shinozaki, Keisho Chin, Masashi Ueno, Nobuyuki Mizunuma, Toshiharu Yamaguchi

Original Article

Gemcitabine plus split-dose cisplatin could be a promising alternative to gemcitabine plus carboplatin for cisplatin-unfit patients with advanced urothelial carcinoma

Yi Rang Kim, Jae Lyun Lee, Dalsan You, In Gab Jeong, Cheryn Song, Bumsik Hong, Jun Hyuk Hong, Hanjong Ahn

Original Article

Phase II study of erlotinib in elderly patients with non-small cell lung cancer harboring epidermal growth factor receptor mutations

Yusuke Inoue, Naoki Inui, Kazuhiro Asada, Masato Karayama, Hiroyuki Matsuda, Koshi Yokomura, Naoki Koshimizu, Shiro Imokawa, Takashi Yamada, Toshihiro Shirai, Norio Kasamatsu, Takafumi Suda

Original Article

Correlation between BRCA1 and TopBP1 protein expression and clinical outcome of non-small cell lung cancer treated with platinum-based chemotherapy

Lin-run Wang, Lin-Juan He, Yang Wang, Yin-yan Li, Yan Lou, Guo-bing Zhang, Ying Li, Jian Chen

Original Article

A single-dose PK study of onapristone including the effect of food on absorption

Keyvan Rezai, Didier Chassard, Caroline Denot, Stefan Proniuk, Alexander Zukiwski, Erard Gilles, Haydeé L. Ramos, Alain Patat, Alice Bexon, François Lokiec

Original Article

Inhibition of prostate cancer cell growth by 3′,4′,5′-trimethoxyflavonol (TMFol)

C. U. F. Kelly Hill, Shaban E. A. Saad, Robert G. Britton, Andreas J. Gescher, Stewart Sale, Karen Brown, Lynne M. Howells

Original Article

Pharmacodynamic study of axitinib in patients with advanced malignancies assessed with 18F-3′deoxy-3′fluoro-l-thymidine positron emission tomography/computed tomography

Justine Yang Bruce, Peter Colin Scully, Lakeesha L. Carmichael, Jens C. Eickhoff, Scott B. Perlman, Jill Marie Kolesar, Jennifer L. Heideman, Robert Jeraj, Glenn Liu

Clinical Trial Report

A phase II study of biweekly S-1 and paclitaxel (SPA) as first-line chemotherapy in patients with metastatic or advanced gastric cancer

Haiping Jiang, Jiong Qian, Peng Zhao, Xiaochen Zhang, Yi Zheng, Chenyu Mao, Yulong Zheng, Linghong Chen, Yao Wang, Haibo Mou, Weijia Fang, Lisong Teng, Nong Xu

Short Communication

Effect of bendamustine in combination with rituximab on QT interval duration in patients with advanced de novo indolent non-Hodgkin or mantle cell lymphoma

John M. Burke, Richard H. C. van der Jagt, Ian W. Flinn, Michael D. Craig, Ling Chen, Joel Morganroth, Mihaela C. Munteanu, David A. MacDonald

Erratum

Erratum to: Docetaxel, cisplatin, and fluorouracil combination in neoadjuvant setting in the treatment of locally advanced gastric adenocarcinoma: Phase II NEOTAX study

Nuriye Ozdemir, Huseyin Abali, Murat Vural, Suayib Yalcin, Berna Oksuzoglu, Burak Civelek, Dilek Oguz, Birol Bostanci, Bulent Yalcin, Nurullah Zengin

Webinar | 19-02-2024 | 17:30 (CET)

Keynote webinar | Spotlight on antibody–drug conjugates in cancer

Antibody–drug conjugates (ADCs) are novel agents that have shown promise across multiple tumor types. Explore the current landscape of ADCs in breast and lung cancer with our experts, and gain insights into the mechanism of action, key clinical trials data, existing challenges, and future directions.

Dr. Véronique Diéras
Prof. Fabrice Barlesi
Developed by: Springer Medicine