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Published in: BMC Public Health 1/2019

Open Access 01-12-2019 | Research article

Cancer and how the patients see it; prevalence and perception of risk factors: a cross-sectional survey from a tertiary care centre of Karachi, Pakistan

Authors: Saira Saeed, Javaid Ahmad Khan, Nousheen Iqbal, Sana Irfan, Alviya Shafique, Safia Awan

Published in: BMC Public Health | Issue 1/2019

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Abstract

Background

The incidence of cancer is rising but data available regarding prevalence of cancer and patient perception of the disease in Pakistan is limited. It is difficult to deal with Cancer if the main causes are negligence towards risk factors and bizarre myths. This study was aimed to investigate common cancer presentations at a government sector hospital and to gain insight into patient knowledge of the disease.

Methods

This was a cross-sectional study conducted on cancer patients from Jinnah Postgraduate Medical Centre. A self-made questionnaire was used to assess the norms related to cancer prevalence in our society, associated myths, and the most common risk factors per them.

Results

A total of 402 participants consented to participate in the study (mean age 42.3 ± 15.07 years), 204(50.7%) were females and 190(47.3%) were illiterate. Biomass exposure was found in 147(37%), drug abuse in 132(33%) and smoking in 63(16%). We found 103(25.6%) had positive family histories of cancer. The most common primary tumor site was breast for females 98(48%) and Head and neck 66(33.3%) for males. Patients considered fate 328(82%), gutka 284(71%) and injuries 282(70%) as the most common causes for cancer; while 222(55.5%) considered black magic and 236(58.75%) considered evil eye as a risk factor for cancer. Cancer treatment caused significant financial stress in 376(93.5%) patients.

Conclusion

Breast and head and neck cancers were found to be prevalent among patients. It was noted that patients are negligent in daily life regarding the consumption of substances that commonly cause cancer. Individuals had diminished knowledge and majority linked cancer to unrelated causes and myths like black magic and fate. Almost all the patients complained of severe financial stress imposed by the disease.
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Literature
3.
go back to reference Ferlay J, Soerjomataram I, Dikshit R, Eser S, Mathers C, Rebelo M, et al. Cancer incidence and mortality worldwide: sources, methods and major patterns in GLOBOCAN 2012. Int J Cancer. 2014;136(5):E359–86.CrossRef Ferlay J, Soerjomataram I, Dikshit R, Eser S, Mathers C, Rebelo M, et al. Cancer incidence and mortality worldwide: sources, methods and major patterns in GLOBOCAN 2012. Int J Cancer. 2014;136(5):E359–86.CrossRef
4.
go back to reference Sarwar M, Saqib A. Cancer prevalence, incidence and mortality rates in Pakistan in 2012. Cogent Medicine. 2017;4(1). Sarwar M, Saqib A. Cancer prevalence, incidence and mortality rates in Pakistan in 2012. Cogent Medicine. 2017;4(1).
5.
go back to reference Montesano R, Hall J. Environmental causes of human cancers. Eur J Cancer. 2001;37:67–87.CrossRef Montesano R, Hall J. Environmental causes of human cancers. Eur J Cancer. 2001;37:67–87.CrossRef
6.
go back to reference Ferber M, Montoya D, Yu C, Aderca I, McGee A, Thorland E, et al. Integrations of the hepatitis B virus (HBV) and human papillomavirus (HPV) into the human telomerase reverse transcriptase (hTERT) gene in liver and cervical cancers. Oncogene. 2003;22(24):3813–20.CrossRef Ferber M, Montoya D, Yu C, Aderca I, McGee A, Thorland E, et al. Integrations of the hepatitis B virus (HBV) and human papillomavirus (HPV) into the human telomerase reverse transcriptase (hTERT) gene in liver and cervical cancers. Oncogene. 2003;22(24):3813–20.CrossRef
7.
go back to reference Yu M, Yuan J. Environmental factors and risk for hepatocellular carcinoma. Gastroenterology. 2004;127(5):S72–8.CrossRef Yu M, Yuan J. Environmental factors and risk for hepatocellular carcinoma. Gastroenterology. 2004;127(5):S72–8.CrossRef
8.
go back to reference Hashibe M, Brennan P, Chuang S, Boccia S, Castellsague X, Chen C, et al. Interaction between tobacco and alcohol use and the risk of head and neck Cancer: pooled analysis in the international head and neck Cancer epidemiology consortium. Cancer Epidemiol Biomark Prev. 2009;18(2):541–50.CrossRef Hashibe M, Brennan P, Chuang S, Boccia S, Castellsague X, Chen C, et al. Interaction between tobacco and alcohol use and the risk of head and neck Cancer: pooled analysis in the international head and neck Cancer epidemiology consortium. Cancer Epidemiol Biomark Prev. 2009;18(2):541–50.CrossRef
9.
go back to reference Jafar T, Haaland B, Rahman A, Razzak J, Bilger M, Naghavi M, et al. Non-communicable diseases and injuries in Pakistan: strategic priorities. Lancet. 2013;381(9885):2281–90.CrossRef Jafar T, Haaland B, Rahman A, Razzak J, Bilger M, Naghavi M, et al. Non-communicable diseases and injuries in Pakistan: strategic priorities. Lancet. 2013;381(9885):2281–90.CrossRef
11.
go back to reference Edgren G, Liang L, Adami H, Chang E. Enigmatic sex disparities in cancer incidence. Eur J Epidemiol. 2012;27(3):187–96.CrossRef Edgren G, Liang L, Adami H, Chang E. Enigmatic sex disparities in cancer incidence. Eur J Epidemiol. 2012;27(3):187–96.CrossRef
12.
go back to reference Aziz Z, Sana S, Akram M, Saeed A. Socioeconomic status and breast cancer survival in Pakistani women. J Pak Med Assoc. 2004;54(9):448–53.PubMed Aziz Z, Sana S, Akram M, Saeed A. Socioeconomic status and breast cancer survival in Pakistani women. J Pak Med Assoc. 2004;54(9):448–53.PubMed
13.
go back to reference Eriksson H, Lyth J, Månsson-Brahme E, Frohm-Nilsson M, Ingvar C, Lindholm C, et al. Low level of education is associated with later stage at diagnosis and reduced survival in cutaneous malignant melanoma: a nationwide population-based study in Sweden. Eur J Cancer. 2013;49(12):2705–16.CrossRef Eriksson H, Lyth J, Månsson-Brahme E, Frohm-Nilsson M, Ingvar C, Lindholm C, et al. Low level of education is associated with later stage at diagnosis and reduced survival in cutaneous malignant melanoma: a nationwide population-based study in Sweden. Eur J Cancer. 2013;49(12):2705–16.CrossRef
14.
go back to reference Mwaka A, Garimoi C, Were E, Roland M, Wabinga H, Lyratzopoulos G. Social, demographic and healthcare factors associated with stage at diagnosis of cervical cancer: cross-sectional study in a tertiary hospital in northern Uganda. BMJ Open. 2016;6(1):e007690.CrossRef Mwaka A, Garimoi C, Were E, Roland M, Wabinga H, Lyratzopoulos G. Social, demographic and healthcare factors associated with stage at diagnosis of cervical cancer: cross-sectional study in a tertiary hospital in northern Uganda. BMJ Open. 2016;6(1):e007690.CrossRef
15.
go back to reference Lee L, Cheung W, Atkinson E, Krzyzanowska M. Impact of comorbidity on chemotherapy use and outcomes in solid tumors: a systematic review. J Clin Oncol. 2011;29(1):106–17.CrossRef Lee L, Cheung W, Atkinson E, Krzyzanowska M. Impact of comorbidity on chemotherapy use and outcomes in solid tumors: a systematic review. J Clin Oncol. 2011;29(1):106–17.CrossRef
16.
go back to reference Edwards B, Noone A, Mariotto A, Simard E, Boscoe F, Henley S, et al. Annual report to the nation on the status of cancer, 1975-2010, featuring prevalence of comorbidity and impact on survival among persons with lung, colorectal, breast, or prostate cancer. Cancer. 2013;120(9):1290–314.CrossRef Edwards B, Noone A, Mariotto A, Simard E, Boscoe F, Henley S, et al. Annual report to the nation on the status of cancer, 1975-2010, featuring prevalence of comorbidity and impact on survival among persons with lung, colorectal, breast, or prostate cancer. Cancer. 2013;120(9):1290–314.CrossRef
17.
go back to reference Piccirillo J. Prognostic importance of comorbidity in a hospital-based Cancer registry. JAMA. 2004;291(20):2441.CrossRef Piccirillo J. Prognostic importance of comorbidity in a hospital-based Cancer registry. JAMA. 2004;291(20):2441.CrossRef
18.
go back to reference Masood K, Masood A, Zafar J, Shahid A, Kamran M, et al. Trends and analysis of Cancer incidence for common male and female cancers in the population of Punjab Province of Pakistan during 1984 to 2014. Asian Pac J Cancer Prev. 2015;16(13):5297–304.CrossRef Masood K, Masood A, Zafar J, Shahid A, Kamran M, et al. Trends and analysis of Cancer incidence for common male and female cancers in the population of Punjab Province of Pakistan during 1984 to 2014. Asian Pac J Cancer Prev. 2015;16(13):5297–304.CrossRef
19.
go back to reference Straif K, Baan R, Grosse Y, Secretan B, El Ghissassi F, Cogliano V. Carcinogenicity of household solid fuel combustion and of high-temperature frying. The Lancet Oncology. 2006;7(12):977–8.CrossRef Straif K, Baan R, Grosse Y, Secretan B, El Ghissassi F, Cogliano V. Carcinogenicity of household solid fuel combustion and of high-temperature frying. The Lancet Oncology. 2006;7(12):977–8.CrossRef
20.
go back to reference Serra C, Kogevinas M, Silverman D, Turuguet D, Tardon A, Garcia-Closas R, et al. Work in the textile industry in Spain and bladder cancer. Occup Environ Med. 2007;65(8):552–9.CrossRef Serra C, Kogevinas M, Silverman D, Turuguet D, Tardon A, Garcia-Closas R, et al. Work in the textile industry in Spain and bladder cancer. Occup Environ Med. 2007;65(8):552–9.CrossRef
21.
go back to reference Elliott L, Loomis D, Dement J, Hein M, Richardson D, Stayner L. Lung cancer mortality in North Carolina and South Carolina chrysotile asbestos textile workers. Occup Environ Med. 2012;69(6):385–90.CrossRef Elliott L, Loomis D, Dement J, Hein M, Richardson D, Stayner L. Lung cancer mortality in North Carolina and South Carolina chrysotile asbestos textile workers. Occup Environ Med. 2012;69(6):385–90.CrossRef
22.
go back to reference Paluch-Shimon S, Cardoso F, Sessa C, Balmana J, Cardoso M, Gilbert F, et al. Prevention and screening in BRCA mutation carriers and other breast/ovarian hereditary cancer syndromes: ESMO clinical practice guidelines for cancer prevention and screening. Ann Oncol. 2016;27(suppl_5):v103–10.CrossRef Paluch-Shimon S, Cardoso F, Sessa C, Balmana J, Cardoso M, Gilbert F, et al. Prevention and screening in BRCA mutation carriers and other breast/ovarian hereditary cancer syndromes: ESMO clinical practice guidelines for cancer prevention and screening. Ann Oncol. 2016;27(suppl_5):v103–10.CrossRef
23.
go back to reference Franca-Botelho A, Ferreira M, Franca J, Franca E, Honorio-Franca A. Breastfeeding and its relationship with reduction of breast Cancer: a review. Asian Pac J Cancer Prev. 2012;13(11):5327–32.CrossRef Franca-Botelho A, Ferreira M, Franca J, Franca E, Honorio-Franca A. Breastfeeding and its relationship with reduction of breast Cancer: a review. Asian Pac J Cancer Prev. 2012;13(11):5327–32.CrossRef
24.
go back to reference Mosquera I, Vergara I, Larrañaga I, Machón M, del Río M, Calderón C. Measuring the impact of informal elderly caregiving: a systematic review of tools. Qual Life Res. 2015;25(5):1059–92.CrossRef Mosquera I, Vergara I, Larrañaga I, Machón M, del Río M, Calderón C. Measuring the impact of informal elderly caregiving: a systematic review of tools. Qual Life Res. 2015;25(5):1059–92.CrossRef
Metadata
Title
Cancer and how the patients see it; prevalence and perception of risk factors: a cross-sectional survey from a tertiary care centre of Karachi, Pakistan
Authors
Saira Saeed
Javaid Ahmad Khan
Nousheen Iqbal
Sana Irfan
Alviya Shafique
Safia Awan
Publication date
01-12-2019
Publisher
BioMed Central
Published in
BMC Public Health / Issue 1/2019
Electronic ISSN: 1471-2458
DOI
https://doi.org/10.1186/s12889-019-6667-7

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