Skip to main content
Top
Published in: World Journal of Emergency Surgery 1/2015

Open Access 01-12-2015 | Review

Can we respect the principles of oncologic resection in an emergency surgery to treat colon cancer?

Authors: Frederico Teixeira, Eduardo Hiroshi Akaishi, Adriano Zuardi Ushinohama, Tiago Cypriano Dutra, Sérgio Dias do Couto Netto, Edivaldo Massazo Utiyama, Celso Oliveira Bernini, Samir Rasslan

Published in: World Journal of Emergency Surgery | Issue 1/2015

Login to get access

Abstract

Patients with colorectal cancer admitted to the emergency room are generally at more advanced stage of the disease and are usually submitted to a resection with curative intent in a smaller scale. In such scenario, one of the aspects to be considered is whether the principles of oncologic resection are observed when those patients diagnosed with colon cancer are treated with surgery. We selected 87 patients with adenocarcinoma of colon and/or upper rectum submitted to an emergency surgical resection. The major variables reviewed retrospectively were: the extent of resection performed, the number of dissected regional lymph nodes and the overall survival rate. Intestinal obstruction was observed in 67 patients (77%) while perforation was found in 20 patients (23%). Seven (8%) specimens had circumferential compromised margins, all found in patients with T4 tumors combine with poor clinical status. The number of dissected regional lymph nodes was greater than, or equal to, 12 in 71% of patients. While the average days of stay in the ICU was 5.7 days, the median was 3 days. The morbidity and peri-operative mortality stood at 33.6% and 20%, respectively. The outcome of an emergency surgery of colorectal cancer observed in this study was similar to those found in the literature. The principles of oncologic resection were respected when considering and analyzing the extent of the resection, the surgical margins and the number of dissected lymph nodes.
Literature
1.
go back to reference Jemal A, Siegel R, Ward E, Murray T, Xu J, Thun MJ: Cancer statistics, 2007. CA Cancer J Clin 2007, 57: 43–66. 10.3322/canjclin.57.1.43PubMedCrossRef Jemal A, Siegel R, Ward E, Murray T, Xu J, Thun MJ: Cancer statistics, 2007. CA Cancer J Clin 2007, 57: 43–66. 10.3322/canjclin.57.1.43PubMedCrossRef
2.
go back to reference Ries LAG, Eisner MP: SEER Cancer Statistics Review, 1973–1997. Bethesda, MD: National Cancer Institute; 2000. Ries LAG, Eisner MP: SEER Cancer Statistics Review, 1973–1997. Bethesda, MD: National Cancer Institute; 2000.
5.
go back to reference Ponz de Leon M, Sassatelli R, Scalmati A, Di Gregorio C, Fante R, Zanguieri G: Descriptive epidemiology of colorectal câncer in Italy: the 6 year experience of a specialized registry. Eur J Cancer 1993,29(3):367–71. 10.1016/0959-8049(93)90389-WCrossRef Ponz de Leon M, Sassatelli R, Scalmati A, Di Gregorio C, Fante R, Zanguieri G: Descriptive epidemiology of colorectal câncer in Italy: the 6 year experience of a specialized registry. Eur J Cancer 1993,29(3):367–71. 10.1016/0959-8049(93)90389-WCrossRef
6.
go back to reference Phang PT, MacFarlane JK, Taylor RH, Chiefetz R, Davis N, Hay J: Effect of emergent presentation on outcome from rectal cancer management. Am J Surg 2003, 185: 450–4. 10.1016/S0002-9610(03)00058-8PubMedCrossRef Phang PT, MacFarlane JK, Taylor RH, Chiefetz R, Davis N, Hay J: Effect of emergent presentation on outcome from rectal cancer management. Am J Surg 2003, 185: 450–4. 10.1016/S0002-9610(03)00058-8PubMedCrossRef
7.
go back to reference Scott NA, Jeacock J, Kingston RD: Risk factors in patients presenting as an emergency with colorectal cancer. Br J Surg 1995, 82: 321–3. 10.1002/bjs.1800820311PubMedCrossRef Scott NA, Jeacock J, Kingston RD: Risk factors in patients presenting as an emergency with colorectal cancer. Br J Surg 1995, 82: 321–3. 10.1002/bjs.1800820311PubMedCrossRef
8.
go back to reference Letiman IM, Sullivan JD, Brams D, De Cosse JJ: Multivariate analysis of morbity and mortality from the initial surgical management of obstructing carcinoma of the colon. Surg Gynecol Obstet 1992, 174: 513–8. Letiman IM, Sullivan JD, Brams D, De Cosse JJ: Multivariate analysis of morbity and mortality from the initial surgical management of obstructing carcinoma of the colon. Surg Gynecol Obstet 1992, 174: 513–8.
9.
go back to reference Tekkis PP, Kinsman R, Thompson MR, Statamakis JD: The Association of Coloproctology of Great Britain and Ireland study of large bowel obstruction caused by colorectal cancer. Ann Surg 2004, 240: 76–81. 10.1097/01.sla.0000130723.81866.75PubMedCentralPubMedCrossRef Tekkis PP, Kinsman R, Thompson MR, Statamakis JD: The Association of Coloproctology of Great Britain and Ireland study of large bowel obstruction caused by colorectal cancer. Ann Surg 2004, 240: 76–81. 10.1097/01.sla.0000130723.81866.75PubMedCentralPubMedCrossRef
10.
go back to reference Fielding LP, Wells BW: Survival after primary and after staged resection for large bowel obstrucion caused by cancer. Br J Surg 1974, 61: 16–8. 10.1002/bjs.1800610105PubMedCrossRef Fielding LP, Wells BW: Survival after primary and after staged resection for large bowel obstrucion caused by cancer. Br J Surg 1974, 61: 16–8. 10.1002/bjs.1800610105PubMedCrossRef
11.
go back to reference Runkel NS, Schlag P, Schwarz V, Herfarth C: Outcome after emergency surgery for cancer of the large intestine. Br J Surg 1991, 78: 183–8. 10.1002/bjs.1800780216PubMedCrossRef Runkel NS, Schlag P, Schwarz V, Herfarth C: Outcome after emergency surgery for cancer of the large intestine. Br J Surg 1991, 78: 183–8. 10.1002/bjs.1800780216PubMedCrossRef
12.
go back to reference Runkel NS, Hinz U, Lehnert T, Buhr HJ, Herfarth C: Improved outcome after emergency surgery for cancer of the large intestine. Br J Surg 1998, 85: 1260–5. 10.1046/j.1365-2168.1998.00855.xPubMedCrossRef Runkel NS, Hinz U, Lehnert T, Buhr HJ, Herfarth C: Improved outcome after emergency surgery for cancer of the large intestine. Br J Surg 1998, 85: 1260–5. 10.1046/j.1365-2168.1998.00855.xPubMedCrossRef
13.
go back to reference Kronborg O, Backer O, Sprechler M: Acute obstruction in cancer of the colon and rectum. Dis Colon Rectum 1975,18(1):22. 10.1007/BF02587233PubMedCrossRef Kronborg O, Backer O, Sprechler M: Acute obstruction in cancer of the colon and rectum. Dis Colon Rectum 1975,18(1):22. 10.1007/BF02587233PubMedCrossRef
14.
go back to reference Stower M, Hard CJ: The results of 1115 patients with colorectal cancer treated over an 8-year period in a single hospital. Eur J Surg Oncol 1985,11(2):119–23.PubMed Stower M, Hard CJ: The results of 1115 patients with colorectal cancer treated over an 8-year period in a single hospital. Eur J Surg Oncol 1985,11(2):119–23.PubMed
15.
go back to reference Carraro P, Segala M, Orlotti C, Tiberio G: Outcome of large-bowel perforation in patients with colorectal cancer. Dis Colon Rectum 1998,41(11):1421–6. 10.1007/BF02237060PubMedCrossRef Carraro P, Segala M, Orlotti C, Tiberio G: Outcome of large-bowel perforation in patients with colorectal cancer. Dis Colon Rectum 1998,41(11):1421–6. 10.1007/BF02237060PubMedCrossRef
16.
go back to reference Mandava N, Kumar S, PIzzi WF, Aprille IJ: Perforated colorectal carcinomas. Am J Surg 1996,172(3):236–8. 10.1016/S0002-9610(96)00164-XPubMedCrossRef Mandava N, Kumar S, PIzzi WF, Aprille IJ: Perforated colorectal carcinomas. Am J Surg 1996,172(3):236–8. 10.1016/S0002-9610(96)00164-XPubMedCrossRef
17.
go back to reference Alcobendas F, Jorba R, Poves I, Busquets J, Engel A, Jaurrieta E: Perforated colonic cancer. Evolution and prognosis. Rev Esp Enferm Dig 2000,92(5):326–33.PubMed Alcobendas F, Jorba R, Poves I, Busquets J, Engel A, Jaurrieta E: Perforated colonic cancer. Evolution and prognosis. Rev Esp Enferm Dig 2000,92(5):326–33.PubMed
18.
go back to reference McArdle CS, Mc Millan D, Hole DJ: The impact of blood loss, obstruction and perforation on survival in patients undergoing curative resection for colon cancer. Br J Surg 2006, 93: 383–8.CrossRef McArdle CS, Mc Millan D, Hole DJ: The impact of blood loss, obstruction and perforation on survival in patients undergoing curative resection for colon cancer. Br J Surg 2006, 93: 383–8.CrossRef
19.
go back to reference Smothers L, Hynan L, Fleming J, Turnage R, Simmang C, Anthony T: Emergency surgery for colon carcinoma. Dis Colon Rectum 2003,46(1):24–30. 10.1007/s10350-004-6492-6PubMedCrossRef Smothers L, Hynan L, Fleming J, Turnage R, Simmang C, Anthony T: Emergency surgery for colon carcinoma. Dis Colon Rectum 2003,46(1):24–30. 10.1007/s10350-004-6492-6PubMedCrossRef
20.
go back to reference Tobaruela E, Camuñas J, Navascúes JM E –, Díez M, Ratia T, Martin A, et al.: Medical factors in the morbidity and mortality associated with emergency colorectal cancer surgery. Rev Esp Enferm Dig 1997,89(1):13–22.PubMed Tobaruela E, Camuñas J, Navascúes JM E –, Díez M, Ratia T, Martin A, et al.: Medical factors in the morbidity and mortality associated with emergency colorectal cancer surgery. Rev Esp Enferm Dig 1997,89(1):13–22.PubMed
21.
go back to reference Ascanelli A, Navarra G, Tonini G, Feo C, Zerbinati A, Pozza E, et al.: Early and late outcome after surgery for colorectal cancer: elective versus emergency surgery. Tumori 2003,89(1):36–41.PubMed Ascanelli A, Navarra G, Tonini G, Feo C, Zerbinati A, Pozza E, et al.: Early and late outcome after surgery for colorectal cancer: elective versus emergency surgery. Tumori 2003,89(1):36–41.PubMed
22.
go back to reference Wyrzycovski A, Feliciano DV, George TA, Tremblay LN, Rozycki GS, Murphy TW, et al.: Emergent right hemicolectomies. Am Surg 2005,71(8):653–6. discussion 656–7 Wyrzycovski A, Feliciano DV, George TA, Tremblay LN, Rozycki GS, Murphy TW, et al.: Emergent right hemicolectomies. Am Surg 2005,71(8):653–6. discussion 656–7
23.
go back to reference Candelaria P, Rasslan S, Soldá SC, Parreira JG: Right hemicolectomy for nontraumatic surgical emergencies. Int Surg 2005,90(4):231–5.PubMed Candelaria P, Rasslan S, Soldá SC, Parreira JG: Right hemicolectomy for nontraumatic surgical emergencies. Int Surg 2005,90(4):231–5.PubMed
24.
go back to reference Nelson H, Petrelli N, Carlin A, Couture J, Fleshman J, Guilhem J: Guidelines 2000 for Colon and Rectal Cancer Surgery. J Natl Canc Inst 2001, 93: No. 8. 10.1093/jnci/93.1.8CrossRef Nelson H, Petrelli N, Carlin A, Couture J, Fleshman J, Guilhem J: Guidelines 2000 for Colon and Rectal Cancer Surgery. J Natl Canc Inst 2001, 93: No. 8. 10.1093/jnci/93.1.8CrossRef
25.
go back to reference Chang GJ, Rodriguez-Bigas MA, Skibber JM, Moyer VA: Lymph node evaluation and survival after curative resection of colon cancer: systematic review. J Natl Canc Inst 2007,99(6):433–41. 10.1093/jnci/djk092CrossRef Chang GJ, Rodriguez-Bigas MA, Skibber JM, Moyer VA: Lymph node evaluation and survival after curative resection of colon cancer: systematic review. J Natl Canc Inst 2007,99(6):433–41. 10.1093/jnci/djk092CrossRef
26.
go back to reference Kruscheswisk M, Runkel N, Buhr HJ: Radical resection in obstructing colorectal carcinomas. Int J Colorectal Dis 1998,13(5–6):247–50.CrossRef Kruscheswisk M, Runkel N, Buhr HJ: Radical resection in obstructing colorectal carcinomas. Int J Colorectal Dis 1998,13(5–6):247–50.CrossRef
27.
go back to reference McArdle CS, Hole DJ: Emergency presentation of colorectal cancer is associated with poor 5-year survival. Br J Surg 2004,91(5):605–9. 10.1002/bjs.4456PubMedCrossRef McArdle CS, Hole DJ: Emergency presentation of colorectal cancer is associated with poor 5-year survival. Br J Surg 2004,91(5):605–9. 10.1002/bjs.4456PubMedCrossRef
28.
go back to reference Biondo S, Martí-Raguè J, Kresler E, Parés D, Martín A, Navarro M: A prospective study of outcomes of emergency and elective surgeries for complicated colonic cancer. Am J Surg 2005,189(4):377–83. 10.1016/j.amjsurg.2005.01.009PubMedCrossRef Biondo S, Martí-Raguè J, Kresler E, Parés D, Martín A, Navarro M: A prospective study of outcomes of emergency and elective surgeries for complicated colonic cancer. Am J Surg 2005,189(4):377–83. 10.1016/j.amjsurg.2005.01.009PubMedCrossRef
29.
go back to reference Alvarez JA, Baldonedo RF, Bear IG, Truán N, Pire G, Alvarez P: Presentation, treatment, and multivariate analysis of risk factors for obstructive and perforative colorectal carcinoma. Am J Surg 2005,190(3):376–82. 10.1016/j.amjsurg.2005.01.045PubMedCrossRef Alvarez JA, Baldonedo RF, Bear IG, Truán N, Pire G, Alvarez P: Presentation, treatment, and multivariate analysis of risk factors for obstructive and perforative colorectal carcinoma. Am J Surg 2005,190(3):376–82. 10.1016/j.amjsurg.2005.01.045PubMedCrossRef
30.
go back to reference Chiarugi M, Galatioto C, Panicucci S, Scasa F, Zocco G, Seccia M: Oncologic colon cancer resection in emergency: are we doing enough? Surg Oncol 2007,16(Suppl 1):S73–7.PubMedCrossRef Chiarugi M, Galatioto C, Panicucci S, Scasa F, Zocco G, Seccia M: Oncologic colon cancer resection in emergency: are we doing enough? Surg Oncol 2007,16(Suppl 1):S73–7.PubMedCrossRef
31.
go back to reference MacArdle CS, Hole DJ: Influence of volume and specialization on survival following surgery for colorectal cancer. Br J Surg 2004, 91: 610–7. 10.1002/bjs.4476CrossRef MacArdle CS, Hole DJ: Influence of volume and specialization on survival following surgery for colorectal cancer. Br J Surg 2004, 91: 610–7. 10.1002/bjs.4476CrossRef
Metadata
Title
Can we respect the principles of oncologic resection in an emergency surgery to treat colon cancer?
Authors
Frederico Teixeira
Eduardo Hiroshi Akaishi
Adriano Zuardi Ushinohama
Tiago Cypriano Dutra
Sérgio Dias do Couto Netto
Edivaldo Massazo Utiyama
Celso Oliveira Bernini
Samir Rasslan
Publication date
01-12-2015
Publisher
BioMed Central
Published in
World Journal of Emergency Surgery / Issue 1/2015
Electronic ISSN: 1749-7922
DOI
https://doi.org/10.1186/1749-7922-10-5

Other articles of this Issue 1/2015

World Journal of Emergency Surgery 1/2015 Go to the issue