Top

Published in:

01-12-2010 | LETTER TO THE EDITOR

Can prevalence of apolipoprotein E epsilon 4 allele explain the geographical variation of coronary heart disease mortality rates in Western Europe?

Authors: Hong-Liang Zhang, Yi Yang, Jiang Wu

Published in: European Journal of Epidemiology | Issue 12/2010

Excerpt

In the Letter to the Editor by Grant [1], the author suggested geographical differences in APOE genotype distribution as an alternative hypothesis to explain the inverse correlation between incident solar radiation and coronary heart disease (CHD) mortality rates in Western Europe. However, we have some concern about this hypothesis. …

Grant WB. Prevalence of apolipoprotein E epsilon4 allele may explain the geographical variation of coronary heart disease mortality rates in Western Europe. Eur J Epidemiol. 2010;25(9):667.CrossRefPubMed

Gerdes LU. The common polymorphism of apolipoprotein E: geographical aspects and new pathophysiological relations. Clin Chem Lab Med. 2003;41:628–31.CrossRefPubMed

Gerdes LU, Klausen IC, Sihm I, et al. Apolipoprotein E polymorphism in a Danish population compared to findings in 45 other study populations around the world. Genet Epidemiol. 1992;9:155–67.CrossRefPubMed

Wong A. Incident solar radiation and coronary heart disease mortality rates in Europe. Eur J Epidemiol. 2008;23:609–14.CrossRefPubMed

Fullerton SM, Clark AG, Weiss KM, Nickerson DA, Taylor SL, Stengârd JH, et al. Apolipoprotein E variation at the sequence haplotype level: implications for the origin and maintenance of a major human polymorphism. Am J Hum Genet. 2000;67:881–900.CrossRefPubMed

Hanlon CS, Rubinsztein DC. Arginine residues at codons 112 and 158 in the apolipoprotein E gene correspond to the ancestral state in humans. Atherosclerosis. 1995;112:85–90.CrossRefPubMed

Rothman KJ, Greenland S. Causation and causal inference in epidemiology. Am J Pub Health. 2005;95:S144–50.CrossRef

Prakash S, Mehta NC, Dabhi AS, Lakhani O, Khilari M, Shah ND. The prevalence of headache may be related with the latitude: a possible role of Vitamin D insufficiency? J Headache Pain. 2010;11:301–7.CrossRefPubMed

Yi Y, Zhang HL, Wu J. Is headache related with Vitamin D insufficiency? J Headache Pain. 2010;11:369.CrossRef

10.

Zhang HL, Wu J, Zhu J. The immune-modulatory role of apolipoprotein E with emphasis on multiple sclerosis and experimental autoimmune encephalomyelitis. Clin Dev Immunol. 2010;2010:186813.PubMed

11.

Beretich BD, Beretich TM. Explaining multiple sclerosis prevalence by ultraviolet exposure: a geospatial analysis. Mult Scler. 2009;15:891–8.CrossRefPubMed

Title: Can prevalence of apolipoprotein E epsilon 4 allele explain the geographical variation of coronary heart disease mortality rates in Western Europe?
Authors: Hong-Liang Zhang
Yi Yang
Jiang Wu
Publication date: 01-12-2010
Publisher: Springer Netherlands
Published in: European Journal of Epidemiology / Issue 12/2010
Print ISSN: 0393-2990
Electronic ISSN: 1573-7284
DOI: https://doi.org/10.1007/s10654-010-9509-6

At a glance: The STEP trials

Springer Medicine

Can prevalence of apolipoprotein E epsilon 4 allele explain the geographical variation of coronary heart disease mortality rates in Western Europe?

Excerpt

At a glance: The STEP trials

Springer Medicine

Excerpt

Please log in to get access to this content

Other articles of this Issue 12/2010

Cyp1B1 mRNA expression in correlation to cotinine levels with respect to the Cyp1B1 L432V gene polymorphism

A note of thanks

The Shanghai Changfeng Study: a community-based prospective cohort study of chronic diseases among middle-aged and elderly: objectives and design

Early life patterns of common infection: a latent class analysis

Conrad Keating: Smoking kills—the revolutionary life of Richard Doll

Models of population-based analyses for data collected from large extended families