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Knee Surgery, Sports Traumatology, Arthroscopy

Published in:

01-07-2016 | Shoulder

Can platelet-rich plasma have a role in Achilles tendon surgical repair?

Authors: Angelo De Carli, Riccardo Maria Lanzetti, Alessandro Ciompi, Domenico Lupariello, Antonio Vadalà, Giuseppe Argento, Andrea Ferretti, M. C. Vulpiani, M. Vetrano

Published in: Knee Surgery, Sports Traumatology, Arthroscopy | Issue 7/2016

Abstract

Purpose

Our hypothesis was that the Achilles tendon healing process after surgical treatment would be promoted by PRP with a faster return to sports activities.

Methods

Thirty patients with Achilles tendon rupture and surgically treated with a combined mini-open and percutaneous technique were prospectively enroled in the study. Patients were alternately case-by-case assigned to Group A (control group; 15 patients) or Group B (study group; 15 patients). In Group B, PRP was locally infiltrated both during surgery and 14 days after surgery. Patients in both groups were followed up at 1, 3, 6 and 24 months post-operatively via physical examination, VAS, FAOS and VISA-A scales; ultrasonography (US) and MRI were also conducted at one and 6 months; at the 6-month follow-up, isokinetic and jumping capacity tests were also performed.

Results

The VAS, FAOS and VISA-A scale showed no difference between the two groups at 1, 3, 6 and 24 months post-operatively. Isokinetic evaluation showed no differences at both angular speeds. Jumping evaluation showed no difference at 6 months. Also US evaluation showed no differences. MRI data analysis before administration of gadolinium did not reveal significant differences between the two groups. Moreover, after intravenous injection of gadolinium, patients in Group B showed signal enhancement in 30 % of patients compared to 80 % in Group A at 6 months, as indirect evidence of better tendon remodelling (P < 0.05).

Conclusions

A substantial equivalence in structural and functional results in Achilles tendon ruptures surgically treated with and without addition of PRP is shown by present study. Clinical results, morphological features and jumping capability were similar in both groups. The addition of PRP to the surgical treatment of Achilles tendon rupture does not appear to offer superior clinical and functional results.

Level of evidence

IV.

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Title: Can platelet-rich plasma have a role in Achilles tendon surgical repair?
Authors: Angelo De Carli
Riccardo Maria Lanzetti
Alessandro Ciompi
Domenico Lupariello
Antonio Vadalà
Giuseppe Argento
Andrea Ferretti
M. C. Vulpiani
M. Vetrano
Publication date: 01-07-2016
Publisher: Springer Berlin Heidelberg
Published in: Knee Surgery, Sports Traumatology, Arthroscopy / Issue 7/2016
Print ISSN: 0942-2056
Electronic ISSN: 1433-7347
DOI: https://doi.org/10.1007/s00167-015-3580-1

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Can platelet-rich plasma have a role in Achilles tendon surgical repair?

Abstract

Purpose

Methods

Results

Conclusions

Level of evidence

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Abstract

Purpose

Methods

Results

Conclusions

Level of evidence

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