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Published in: BMC Health Services Research 1/2008

Open Access 01-12-2008 | Correspondence

Can modeling of HIV treatment processes improve outcomes? Capitalizing on an operations research approach to the global pandemic

Authors: Wei Xiong, Nathaniel Hupert, Eric B Hollingsworth, Megan E O'Brien, Jessica Fast, William R Rodriguez

Published in: BMC Health Services Research | Issue 1/2008

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Abstract

Background

Mathematical modeling has been applied to a range of policy-level decisions on resource allocation for HIV care and treatment. We describe the application of classic operations research (OR) techniques to address logistical and resource management challenges in HIV treatment scale-up activities in resource-limited countries.

Methods

We review and categorize several of the major logistical and operational problems encountered over the last decade in the global scale-up of HIV care and antiretroviral treatment for people with AIDS. While there are unique features of HIV care and treatment that pose significant challenges to effective modeling and service improvement, we identify several analogous OR-based solutions that have been developed in the service, industrial, and health sectors.

Results

HIV treatment scale-up includes many processes that are amenable to mathematical and simulation modeling, including forecasting future demand for services; locating and sizing facilities for maximal efficiency; and determining optimal staffing levels at clinical centers. Optimization of clinical and logistical processes through modeling may improve outcomes, but successful OR-based interventions will require contextualization of response strategies, including appreciation of both existing health care systems and limitations in local health workforces.

Conclusion

The modeling techniques developed in the engineering field of operations research have wide potential application to the variety of logistical problems encountered in HIV treatment scale-up in resource-limited settings. Increasing the number of cross-disciplinary collaborations between engineering and public health will help speed the appropriate development and application of these tools.
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Metadata
Title
Can modeling of HIV treatment processes improve outcomes? Capitalizing on an operations research approach to the global pandemic
Authors
Wei Xiong
Nathaniel Hupert
Eric B Hollingsworth
Megan E O'Brien
Jessica Fast
William R Rodriguez
Publication date
01-12-2008
Publisher
BioMed Central
Published in
BMC Health Services Research / Issue 1/2008
Electronic ISSN: 1472-6963
DOI
https://doi.org/10.1186/1472-6963-8-166

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