Skip to main content
Top
Published in: Cost Effectiveness and Resource Allocation 1/2013

Open Access 01-12-2013 | Methodology

Calculating disability-adjusted-life-years lost (DALYs) in discrete-time

Author: Bruce A Larson

Published in: Cost Effectiveness and Resource Allocation | Issue 1/2013

Login to get access

Abstract

Disability-adjusted-life-years lost (DALYs) is a common outcome metric for cost-effectiveness analyses, and the equations used for such calculations have been presented previously by Fox-Rushby and Hanson (see, e.g., “Health Policy and Planning 16:326–331, 2001”). While the equations are clear, the logic behind them is opaque at best for a large share of public health practitioners and students. The objective of this paper is to show how to calculate DALYs using a discrete time formulation that is easy to teach to students and public health practitioners, is easy to apply for those with basic discounting skills, and is consistent with the discounting methods typically included on the costing side of cost-effectiveness analysis. A continuous-time adjustment factor is derived that can be used to ensure exact consistency between the continuous and discrete time approaches, but this level of precision is typically unnecessary for cost-effectiveness analyses. To illustrate the approach, both a new, simple example and the same example presented in Fox-Rushby and Hanson are used throughout the paper.
Literature
1.
go back to reference World Bank: World Development Report, Investing in Health 1993. New York, New York: Published for the World Bank, Oxford University Press; 1993.CrossRef World Bank: World Development Report, Investing in Health 1993. New York, New York: Published for the World Bank, Oxford University Press; 1993.CrossRef
2.
go back to reference Murray CJ: Quantifying the burden of disease: the technical basis for disability-adjusted life years. Bull World Health Organ 1994, 72(3):429–45.PubMedCentralPubMed Murray CJ: Quantifying the burden of disease: the technical basis for disability-adjusted life years. Bull World Health Organ 1994, 72(3):429–45.PubMedCentralPubMed
3.
go back to reference Murray CJ, Acharya AK: Understanding DALYs (disability-adjusted life years). J Health Econ 1997, 16(6):703–30. 10.1016/S0167-6296(97)00004-0CrossRefPubMed Murray CJ, Acharya AK: Understanding DALYs (disability-adjusted life years). J Health Econ 1997, 16(6):703–30. 10.1016/S0167-6296(97)00004-0CrossRefPubMed
4.
go back to reference Fox-Rushby J, Hanson K: Calculating and presenting disability adjusted life years (DALYs) in cost-effectiveness analysis. Health Policy Plan 2001, 16(3):326–331. 10.1093/heapol/16.3.326CrossRefPubMed Fox-Rushby J, Hanson K: Calculating and presenting disability adjusted life years (DALYs) in cost-effectiveness analysis. Health Policy Plan 2001, 16(3):326–331. 10.1093/heapol/16.3.326CrossRefPubMed
5.
go back to reference Phanthunane P, et al.: Cost-effectiveness of pharmacological and psychosocial interventions for schizophrenia. Cost Effectiveness and Resource Allocation 2011, 9(1):6. 10.1186/1478-7547-9-6PubMedCentralCrossRefPubMed Phanthunane P, et al.: Cost-effectiveness of pharmacological and psychosocial interventions for schizophrenia. Cost Effectiveness and Resource Allocation 2011, 9(1):6. 10.1186/1478-7547-9-6PubMedCentralCrossRefPubMed
6.
go back to reference Amarasinghe A: Cost-effectiveness implications of GP intervention to promote physical activity: evidence from Perth. Australia. Cost Effectiveness and Resource Allocation 2010, 8(1):10. 10.1186/1478-7547-8-10CrossRefPubMed Amarasinghe A: Cost-effectiveness implications of GP intervention to promote physical activity: evidence from Perth. Australia. Cost Effectiveness and Resource Allocation 2010, 8(1):10. 10.1186/1478-7547-8-10CrossRefPubMed
7.
go back to reference Rubinstein A, et al.: Generalized cost-effectiveness analysis of a package of interventions to reduce cardiovascular disease in Buenos Aires. Argentina. Cost Effectiveness and Resource Allocation 2009, 7(1):10. 10.1186/1478-7547-7-10CrossRefPubMed Rubinstein A, et al.: Generalized cost-effectiveness analysis of a package of interventions to reduce cardiovascular disease in Buenos Aires. Argentina. Cost Effectiveness and Resource Allocation 2009, 7(1):10. 10.1186/1478-7547-7-10CrossRefPubMed
8.
go back to reference Bachmann M: Cost effectiveness of community-based therapeutic care for children with severe acute malnutrition in Zambia: decision tree model. Cost Effectiveness and Resource Allocation 2009, 7(1):2. 10.1186/1478-7547-7-2PubMedCentralCrossRefPubMed Bachmann M: Cost effectiveness of community-based therapeutic care for children with severe acute malnutrition in Zambia: decision tree model. Cost Effectiveness and Resource Allocation 2009, 7(1):2. 10.1186/1478-7547-7-2PubMedCentralCrossRefPubMed
9.
go back to reference Hansen K, Chapman G: Setting priorities for the health care sector in Zimbabwe using cost-effectiveness analysis and estimates of the burden of disease. Cost Effectiveness and Resource Allocation 2008, 6(1):14. 10.1186/1478-7547-6-14PubMedCentralCrossRefPubMed Hansen K, Chapman G: Setting priorities for the health care sector in Zimbabwe using cost-effectiveness analysis and estimates of the burden of disease. Cost Effectiveness and Resource Allocation 2008, 6(1):14. 10.1186/1478-7547-6-14PubMedCentralCrossRefPubMed
10.
go back to reference Dalziel K, Segal L, Mortimer D: Review of Australian health economic evaluation - 245 interventions: what can we say about cost effectiveness? Cost Effectiveness and Resource Allocation 2008, 6(1):9. 10.1186/1478-7547-6-9PubMedCentralCrossRefPubMed Dalziel K, Segal L, Mortimer D: Review of Australian health economic evaluation - 245 interventions: what can we say about cost effectiveness? Cost Effectiveness and Resource Allocation 2008, 6(1):9. 10.1186/1478-7547-6-9PubMedCentralCrossRefPubMed
11.
go back to reference Robberstad B, Hemed Y, Norheim O: Cost-effectiveness of medical interventions to prevent cardiovascular disease in a sub-Saharan African country - the case of Tanzania. Cost Effectiveness and Resource Allocation 2007, 5(1):3. 10.1186/1478-7547-5-3PubMedCentralCrossRefPubMed Robberstad B, Hemed Y, Norheim O: Cost-effectiveness of medical interventions to prevent cardiovascular disease in a sub-Saharan African country - the case of Tanzania. Cost Effectiveness and Resource Allocation 2007, 5(1):3. 10.1186/1478-7547-5-3PubMedCentralCrossRefPubMed
12.
go back to reference Bishai D, Hyder A: Modeling the cost effectiveness of injury interventions in lower and middle income countries: opportunities and challenges. Cost Effectiveness and Resource Allocation 2006, 4(1):2. 10.1186/1478-7547-4-2PubMedCentralCrossRefPubMed Bishai D, Hyder A: Modeling the cost effectiveness of injury interventions in lower and middle income countries: opportunities and challenges. Cost Effectiveness and Resource Allocation 2006, 4(1):2. 10.1186/1478-7547-4-2PubMedCentralCrossRefPubMed
13.
go back to reference Shim E, et al.: Evaluating the cost-effectiveness of rabies post-exposure prophylaxis: A case study in Tanzania. Vaccine 2009, 27(51):7167–7172. 10.1016/j.vaccine.2009.09.027PubMedCentralCrossRefPubMed Shim E, et al.: Evaluating the cost-effectiveness of rabies post-exposure prophylaxis: A case study in Tanzania. Vaccine 2009, 27(51):7167–7172. 10.1016/j.vaccine.2009.09.027PubMedCentralCrossRefPubMed
14.
go back to reference Elbasha EH: Discrete time representation of the formula for calculating DALYs. Health Econ 2000, 9(4):353–365. 10.1002/1099-1050(200006)9:4<353::AID-HEC519>3.0.CO;2-VCrossRefPubMed Elbasha EH: Discrete time representation of the formula for calculating DALYs. Health Econ 2000, 9(4):353–365. 10.1002/1099-1050(200006)9:4<353::AID-HEC519>3.0.CO;2-VCrossRefPubMed
15.
go back to reference Drummond MF: Methods for the Economic Evaluation of Health Care Programmes. 3rd edition. Oxford: Oxford University Press; 2005. Drummond MF: Methods for the Economic Evaluation of Health Care Programmes. 3rd edition. Oxford: Oxford University Press; 2005.
16.
go back to reference Mathers CD, et al.: Chapter 5: Sensitivity and Uncertainty Analyses for Burden of Disease and Risk Factor Estimates. In Global Burden of Disease and Risk Factors. Edited by: Lopez AD. Washington, D.C: The World Bank; 2006. Mathers CD, et al.: Chapter 5: Sensitivity and Uncertainty Analyses for Burden of Disease and Risk Factor Estimates. In Global Burden of Disease and Risk Factors. Edited by: Lopez AD. Washington, D.C: The World Bank; 2006.
Metadata
Title
Calculating disability-adjusted-life-years lost (DALYs) in discrete-time
Author
Bruce A Larson
Publication date
01-12-2013
Publisher
BioMed Central
Published in
Cost Effectiveness and Resource Allocation / Issue 1/2013
Electronic ISSN: 1478-7547
DOI
https://doi.org/10.1186/1478-7547-11-18

Other articles of this Issue 1/2013

Cost Effectiveness and Resource Allocation 1/2013 Go to the issue