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European Spine Journal

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01-05-2013 | Case Report

Calcium pyrophosphate dihydrate deposition disease of the filum terminale

Authors: G. Cacciotti, F. Novegno, D. Fiume

Published in: European Spine Journal | Special Issue 3/2013

Abstract

Introduction

Calcium pyrophosphate dihydrate crystal deposition disease (CPPDD) is a rare benign inflammatory joint disorder characterized by the presence of calcium pyrophosphate dihydrate crystal in the interarticular and periarticular tissue. It has been rarely described with spinal localization.

Methods

A 50-year-old woman, affected by CPPDD, presented a progressive weakness of both lower limbs associated with neurogenic claudication. Neuroradiological examinations revealed the presence of two intradural calcified lesions at level L3–L4, with no post-contrast enhancement.

Results

Surgery was performed and the histopathological exams documented the presence of rod-shaped crystals embedded in a fibrocartilaginous stroma. The postoperative course was uneventful and the patient experienced complete symptoms relief with a 5-year follow-up.

Conclusion

Intradural CPPD localization at the filum terminale is an extremely rare occurrence. Total removal should be preferably attempted with a long-term focal control of the disease as we observed in our case.

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Title: Calcium pyrophosphate dihydrate deposition disease of the filum terminale
Authors: G. Cacciotti
F. Novegno
D. Fiume
Publication date: 01-05-2013
Publisher: Springer-Verlag
Published in: European Spine Journal / Issue Special Issue 3/2013
Print ISSN: 0940-6719
Electronic ISSN: 1432-0932
DOI: https://doi.org/10.1007/s00586-013-2723-7

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Calcium pyrophosphate dihydrate deposition disease of the filum terminale

Abstract

Introduction

Methods

Results

Conclusion

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Abstract

Introduction

Methods

Results

Conclusion

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