Budesonide/Formoterol Combination

Excerpt

The addition of a long acting β₂-agonist to a mild or moderate dose of an inhaled corticosteroid has shown comparable or improved efficacy in achieving asthma control compared with doubling the dosage of inhaled corticosteroid.[1] It appears particularly helpful in improving lung function and reducing asthma exacerbations. The Formoterol and Corticosteroids Establishing Therapy (FACET) trial has shown that in patients with persistent asthma symptoms, despite treatment with inhaled corticosteroids, adding formoterol to budesonide therapy improves both asthma symptoms and peak expiratory flow rates.[2] A subsequent analysis also suggested that long term combination treatment with formoterol and budesonide was not associated with any increase in airway inflammation.[3] …