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Published in: Irish Journal of Medical Science (1971 -) 4/2015

01-12-2015 | Original Article

Buccal mucosa urethroplasty: a 10-year retrospective review of maxillofacial and urological outcomes

Authors: J. E. O’Connell, I. M. Cullen, C. Murphy, H. Flood, G. J. Kearns

Published in: Irish Journal of Medical Science (1971 -) | Issue 4/2015

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Abstract

Background

Reconstruction of a urethral stricture poses a difficult surgical problem. Anastomotic repair remains the gold standard. Strictures longer than 2 cm may require substitution urethroplasty. This is a retrospective review of all patients who underwent urethral reconstruction with an autologous free buccal mucosa graft at a Regional hospital between 1998 and 2009.

Methods

Variables recorded included; demographics: patient gender/age; follow-up period. Urology: pre-operative diagnosis/aetiology; presenting complaint; previous urological surgery, pre-operative retrograde urethrogram, stricture length, graft size, operative time/blood loss, morbidity, complications. Maxillofacial: pre-/post-operative inter-incisal opening, patency of Stenson’s parotid duct, ipsilateral parotid swelling, sensory nerve deficit.

Results

A total of eight male patients were included. Mean age was 33 years. Two patients had one-stage dorsal onlay urethroplasty, and the remaining six had a two-stage BMG urethroplasty. All patients underwent a urethrogram 20 days post-operatively, which demonstrated no leak, and a good caliber grafted urethra in all cases. A flexible cystoscopy scope was accommodated in all patients 8 weeks post-operatively. Mean follow-up was 42 months. At long-term follow-up, there was no evidence of stricture formation, and all patients were voiding well. There were no long-term intra-oral complications.

Conclusion

This study suggests that anterior urethral strictures up to 6 cm in length may be predictably and safely managed with buccal mucosal urethroplasty. The buccal mucosa is easy to harvest, and can be used successfully in one- and two-stage grafting procedures. The rate of complications, from both a urological and maxillofacial perspective, in the group of patients studied was low.
Literature
1.
go back to reference Chapple CR, Patterson JM (2008) Surgical techniques in substitution urethroplasty using buccal mucosa for the treatment of anterior urethral strictures. Eur Urol 53:1162–1171CrossRefPubMed Chapple CR, Patterson JM (2008) Surgical techniques in substitution urethroplasty using buccal mucosa for the treatment of anterior urethral strictures. Eur Urol 53:1162–1171CrossRefPubMed
2.
3.
go back to reference Barbagli G, Lazzeri M (2007) Surgical treatment of anterior urethral stricture diseases: brief overview. Int Braz J Urol 33:461–469PubMed Barbagli G, Lazzeri M (2007) Surgical treatment of anterior urethral stricture diseases: brief overview. Int Braz J Urol 33:461–469PubMed
4.
go back to reference Lumen N, Oosterlinck W, Hoebeke P (2012) Urethral reconstruction using buccal mucosa or penile skin grafts: systematic review and meta-analysis. Urol Int 89(4):387–394CrossRefPubMed Lumen N, Oosterlinck W, Hoebeke P (2012) Urethral reconstruction using buccal mucosa or penile skin grafts: systematic review and meta-analysis. Urol Int 89(4):387–394CrossRefPubMed
5.
go back to reference Mangera A, Chapple C (2010) Management of anterior urethral stricture: an evidence-based approach. Curr Opin Urol 20:453–458CrossRefPubMed Mangera A, Chapple C (2010) Management of anterior urethral stricture: an evidence-based approach. Curr Opin Urol 20:453–458CrossRefPubMed
6.
go back to reference Rogers HS, McNicholas TA, Blandy JP (1992) Long-term results of one-stage scrotal patch urethroplasty. Br J Urol 69(6):621–628CrossRefPubMed Rogers HS, McNicholas TA, Blandy JP (1992) Long-term results of one-stage scrotal patch urethroplasty. Br J Urol 69(6):621–628CrossRefPubMed
7.
go back to reference Webster GD, Brown MW, Koefoot RB Jr, Si-helnick S (1984) Suboptimal results in full-thickness skin graft urethroplasty using an extra-penile skin donor site. J Urol 131:1082–1083PubMed Webster GD, Brown MW, Koefoot RB Jr, Si-helnick S (1984) Suboptimal results in full-thickness skin graft urethroplasty using an extra-penile skin donor site. J Urol 131:1082–1083PubMed
8.
go back to reference Bhargava S, Chapple CR (2004) Buccal mucosal urethroplasty: is it the new gold standard? BJU Int 93:1191–1193CrossRefPubMed Bhargava S, Chapple CR (2004) Buccal mucosal urethroplasty: is it the new gold standard? BJU Int 93:1191–1193CrossRefPubMed
9.
go back to reference Ozgok Y, Ozgur Tan M, Kilciler M, Tahmaz L, Erduran D (2000) Use of bladder mucosal graft for urethral reconstruction. Int J Urol 7:355–360CrossRefPubMed Ozgok Y, Ozgur Tan M, Kilciler M, Tahmaz L, Erduran D (2000) Use of bladder mucosal graft for urethral reconstruction. Int J Urol 7:355–360CrossRefPubMed
10.
go back to reference Xu YM, Qiao Y, Sa YL et al (2009) Urethral reconstruction using colonic mucosa graft for complex strictures. J Urol 182:1040–1043CrossRefPubMed Xu YM, Qiao Y, Sa YL et al (2009) Urethral reconstruction using colonic mucosa graft for complex strictures. J Urol 182:1040–1043CrossRefPubMed
11.
go back to reference Bhargava S, Patterson JM, Inman RD, Mac-Neil S, Chapple CR (2008) Tissue-engineered buccal mucosa urethroplasty-clinical outcomes. Eur Urol 53:1263–1269CrossRefPubMed Bhargava S, Patterson JM, Inman RD, Mac-Neil S, Chapple CR (2008) Tissue-engineered buccal mucosa urethroplasty-clinical outcomes. Eur Urol 53:1263–1269CrossRefPubMed
12.
go back to reference Raya-Rivera A, Esquiliano DR, Yoo JJ et al (2011) Tissue-engineered autologous urethras for patients who need reconstruction: an observational study. Lancet 377:1175–1182PubMedCentralCrossRefPubMed Raya-Rivera A, Esquiliano DR, Yoo JJ et al (2011) Tissue-engineered autologous urethras for patients who need reconstruction: an observational study. Lancet 377:1175–1182PubMedCentralCrossRefPubMed
13.
go back to reference Devine PC, Fallon B, Devine CJ Jr (1976) Free full thickness skin graft urethroplasty. J Urol 116:444–446PubMed Devine PC, Fallon B, Devine CJ Jr (1976) Free full thickness skin graft urethroplasty. J Urol 116:444–446PubMed
14.
go back to reference De Sy W, Oosterlinck W (1978) One-stage urethroplasty with free skin graft. Eur Urol 4:411–413PubMed De Sy W, Oosterlinck W (1978) One-stage urethroplasty with free skin graft. Eur Urol 4:411–413PubMed
15.
16.
go back to reference Burger RA, Muller SC, el-Damanhour H et al (1992) The buccal mucosal graft for urethral reconstruction: a preliminary report. J Urol 147:662–664PubMed Burger RA, Muller SC, el-Damanhour H et al (1992) The buccal mucosal graft for urethral reconstruction: a preliminary report. J Urol 147:662–664PubMed
17.
go back to reference Dubey D, Vijjan V, Kapoor R et al (2007) Dorsal onlay buccal mucosa versus penile skin flap urethroplasty for anterior urethral strictures: results from a randomized prospective trial. J Urol 178:2466–2469CrossRefPubMed Dubey D, Vijjan V, Kapoor R et al (2007) Dorsal onlay buccal mucosa versus penile skin flap urethroplasty for anterior urethral strictures: results from a randomized prospective trial. J Urol 178:2466–2469CrossRefPubMed
18.
go back to reference Brannan W, Oschner MG, Fuselier HA, Goodlet JS (1976) Free full thickness skin graft urethroplasty for urethral stricture: experience with 66 patients. J Urol 115:677–680PubMed Brannan W, Oschner MG, Fuselier HA, Goodlet JS (1976) Free full thickness skin graft urethroplasty for urethral stricture: experience with 66 patients. J Urol 115:677–680PubMed
19.
go back to reference Dubey D, Kumar A, Mandhani A et al (2005) Buccal mucosal urethroplasty: a versatile technique for all urethral segments. BJU Int 95:625–629CrossRefPubMed Dubey D, Kumar A, Mandhani A et al (2005) Buccal mucosal urethroplasty: a versatile technique for all urethral segments. BJU Int 95:625–629CrossRefPubMed
20.
go back to reference Andrich DE, Leach CJ, Mundy AR (2001) The Barbagli procedure gives the best results for patch urethroplasty of the bulbar urethra. BJU Int 88(4):385–389CrossRefPubMed Andrich DE, Leach CJ, Mundy AR (2001) The Barbagli procedure gives the best results for patch urethroplasty of the bulbar urethra. BJU Int 88(4):385–389CrossRefPubMed
21.
go back to reference Pansadoro V, Emiliozzi P, Gaffi M, Scarpone P (1999) Buccal mucosa urethroplasty for the treatment of bulbar urethral strictures. J Urol 161(5):1501–1503CrossRefPubMed Pansadoro V, Emiliozzi P, Gaffi M, Scarpone P (1999) Buccal mucosa urethroplasty for the treatment of bulbar urethral strictures. J Urol 161(5):1501–1503CrossRefPubMed
22.
go back to reference Barbagli G, Selli C, Tosto A, Palminteri E (1996) Dorsal free graft urethroplasty. J Urol 155(1):123–126CrossRefPubMed Barbagli G, Selli C, Tosto A, Palminteri E (1996) Dorsal free graft urethroplasty. J Urol 155(1):123–126CrossRefPubMed
23.
go back to reference Asopa HS, Garg M, Singhal GG, Singh L, Asopa J, Nischal A (2001) Dorsal free graft urethroplasty for anterior urethral stricture by ventral sagittal approach. Urology 58(5):657–659CrossRefPubMed Asopa HS, Garg M, Singhal GG, Singh L, Asopa J, Nischal A (2001) Dorsal free graft urethroplasty for anterior urethral stricture by ventral sagittal approach. Urology 58(5):657–659CrossRefPubMed
24.
go back to reference Grady JD, McCammon K, Schlossberg SM et al (1999) Buccal mucosal graft for penile urethral strictures. J Urol 161:375 Grady JD, McCammon K, Schlossberg SM et al (1999) Buccal mucosal graft for penile urethral strictures. J Urol 161:375
25.
go back to reference Gupta NP, Ansari MS, Dogra PN, Tandon S (2004) Dorsal buccal mucosal graft urethroplasty by a ventral sagittal urethrotomy and minimal-access perineal approach for anterior urethral stricture. BJU Int 93(9):1287–1290CrossRefPubMed Gupta NP, Ansari MS, Dogra PN, Tandon S (2004) Dorsal buccal mucosal graft urethroplasty by a ventral sagittal urethrotomy and minimal-access perineal approach for anterior urethral stricture. BJU Int 93(9):1287–1290CrossRefPubMed
26.
go back to reference Venn SN, Mundy AR (1998) Early experience with the use of buccal mucosa for substitution urethroplasty. Br J Urol 81:738–740CrossRefPubMed Venn SN, Mundy AR (1998) Early experience with the use of buccal mucosa for substitution urethroplasty. Br J Urol 81:738–740CrossRefPubMed
27.
go back to reference Joseph JV, Andrich DE, Leach CJ, Mundy AR (2002) Urethroplasty for refractory anterior urethral stricture. J Urol 167(1):127–129CrossRefPubMed Joseph JV, Andrich DE, Leach CJ, Mundy AR (2002) Urethroplasty for refractory anterior urethral stricture. J Urol 167(1):127–129CrossRefPubMed
28.
go back to reference Palminteri E, Lazzeri M, Guazzoni G, Turini D, Barbagli G (2002) New 2-stage buccal mucosal graft urethroplasty. J Urol 167(1):130–132CrossRefPubMed Palminteri E, Lazzeri M, Guazzoni G, Turini D, Barbagli G (2002) New 2-stage buccal mucosal graft urethroplasty. J Urol 167(1):130–132CrossRefPubMed
29.
go back to reference Tolstunov L, Pogrel A (1996) The free buccal mucosal graft for urethroplasty. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 82(6):613–615CrossRefPubMed Tolstunov L, Pogrel A (1996) The free buccal mucosal graft for urethroplasty. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 82(6):613–615CrossRefPubMed
30.
go back to reference Morey AF, McAninch JW (1996) Technique of harvesting buccal mucosa for urethral reconstruction. J Urol 155(5):1696–1697CrossRefPubMed Morey AF, McAninch JW (1996) Technique of harvesting buccal mucosa for urethral reconstruction. J Urol 155(5):1696–1697CrossRefPubMed
31.
go back to reference Eppley BL, Keating M, Rink R (1997) A buccal mucosal harvesting technique for urethral reconstruction. J Urol 157(4):1268–1270CrossRefPubMed Eppley BL, Keating M, Rink R (1997) A buccal mucosal harvesting technique for urethral reconstruction. J Urol 157(4):1268–1270CrossRefPubMed
32.
go back to reference Wood DN, Allen SE, Andrich DE, Greenwell TJ, Mundy AR (2004) The morbidity of buccal mucosal graft harvest for urethroplasty and the effect of non-closure of the graft harvest site on postoperative pain. J Urol 172(2):580–583CrossRefPubMed Wood DN, Allen SE, Andrich DE, Greenwell TJ, Mundy AR (2004) The morbidity of buccal mucosal graft harvest for urethroplasty and the effect of non-closure of the graft harvest site on postoperative pain. J Urol 172(2):580–583CrossRefPubMed
33.
go back to reference Dublin N, Stewart LH (2004) Oral complications after buccal mucosal graft harvest for urethroplasty. BJU Int 94(6):867–869CrossRefPubMed Dublin N, Stewart LH (2004) Oral complications after buccal mucosal graft harvest for urethroplasty. BJU Int 94(6):867–869CrossRefPubMed
34.
go back to reference Kane CJ, Tarman GJ, Summerton DJ, Buchmann CE, Ward JF, O’Reilly KJ, Ruiz H, Thrasher JB, Zorn B, Smith C, Morey AF (2002) Multi-institutional experience with buccal mucosa onlay urethroplasty for bulbar urethral reconstruction. J Urol 167(3):1314–1317CrossRefPubMed Kane CJ, Tarman GJ, Summerton DJ, Buchmann CE, Ward JF, O’Reilly KJ, Ruiz H, Thrasher JB, Zorn B, Smith C, Morey AF (2002) Multi-institutional experience with buccal mucosa onlay urethroplasty for bulbar urethral reconstruction. J Urol 167(3):1314–1317CrossRefPubMed
35.
go back to reference Caldamone AA, Edstrom LE, Koyle MA, Rabinowitz R, Hulbert WC (1998) Buccal mucosal grafts for urethral reconstruction. Urology 51(5A Suppl):15–19CrossRefPubMed Caldamone AA, Edstrom LE, Koyle MA, Rabinowitz R, Hulbert WC (1998) Buccal mucosal grafts for urethral reconstruction. Urology 51(5A Suppl):15–19CrossRefPubMed
36.
go back to reference Wessells H, McAninch JW (1996) Use of free grafts in urethral stricture reconstruction. J Urol 155(6):1912–1915CrossRefPubMed Wessells H, McAninch JW (1996) Use of free grafts in urethral stricture reconstruction. J Urol 155(6):1912–1915CrossRefPubMed
37.
go back to reference Barbagli G, Guazzoni G, Lazzeri M (2008) One-stage bulbar urethroplasty: retrospective analysis of the results in 375 patients. Eur Urol 53(4):828–833CrossRefPubMed Barbagli G, Guazzoni G, Lazzeri M (2008) One-stage bulbar urethroplasty: retrospective analysis of the results in 375 patients. Eur Urol 53(4):828–833CrossRefPubMed
38.
go back to reference Berger AP, Deibl M, Bartsch G, Steiner H, Varkarakis J, Gozzi C (2005) A comparison of one-stage procedures for post-traumatic urethral stricture repair. BJU Int 95(9):1299–1302CrossRefPubMed Berger AP, Deibl M, Bartsch G, Steiner H, Varkarakis J, Gozzi C (2005) A comparison of one-stage procedures for post-traumatic urethral stricture repair. BJU Int 95(9):1299–1302CrossRefPubMed
39.
go back to reference Meeks JJ, Erickson BA, Gonzalez CM (2009) Staged reconstruction of long segment urethral strictures in men with previous pediatric hypospadias repair. J Urol 181(2):685–689CrossRefPubMed Meeks JJ, Erickson BA, Gonzalez CM (2009) Staged reconstruction of long segment urethral strictures in men with previous pediatric hypospadias repair. J Urol 181(2):685–689CrossRefPubMed
Metadata
Title
Buccal mucosa urethroplasty: a 10-year retrospective review of maxillofacial and urological outcomes
Authors
J. E. O’Connell
I. M. Cullen
C. Murphy
H. Flood
G. J. Kearns
Publication date
01-12-2015
Publisher
Springer London
Published in
Irish Journal of Medical Science (1971 -) / Issue 4/2015
Print ISSN: 0021-1265
Electronic ISSN: 1863-4362
DOI
https://doi.org/10.1007/s11845-014-1165-5

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