Skip to main content
Top
Published in: BMC Oral Health 1/2023

Open Access 01-12-2023 | Bruxism | Research

The contribution of genetics to dental caries, oral habits and occlusal traits in Turkish twins: A comparative study

Authors: Esra Oz, Zuhal Kırzıoglu

Published in: BMC Oral Health | Issue 1/2023

Login to get access

Abstract

Objective

The aims of this study were to investigate and compare the prevalence of dental caries and the frequency of oral habits, molar relationships and occlusal traits between children of multiple births, and singletons, and to determine the relative contributions of genetics and environmental factors to these parameters by using twin study design.

Methods

The study group consisted of 345 multiple births (34 monozygotic and 122 dizygotic twin pairs, 11 sets of triplets) and 345 singletons between the ages of 2 and 17. The prevalence of dental caries, and the frequency of tooth brushing, the children’s oral habits, molar relationships, and occlusal traits were recorded.

Results

The percentage of children who brushed their teeth more than twice daily was statistically significantly higher in multiple births than in singletons. Higher correlation coefficients were found in dental caries index, except for decayed, filled (df) (2–5 age group) and filled (f) (6–11 age group), in the monozygotic twin pairs compared to those in the dizygotic twin pairs. In children between the ages of 6 and 11 years, mouth breathing, bruxism, lip biting, and pencil biting were higher in singletons than in children of multiple births. There were statistically significant differences between children of multiple births and singletons, with increased overjet in the 2–5 year age group being observed.

Conclusion

When analyzing these parameters, environmental factors must also be investigated. Due to the low incidence of twin births, longitudinal follow-up studies with more twin pairs are necessary to determine whether these results are generalizable.
Literature
1.
go back to reference Hughes TE, Townsend GC, Pinkerton SK, Bockmann MR, Seow WK, Brook AH, et al. The teeth and faces of twins: providing insights into dentofacial development and oral health for practising oral health professionals. Aust Dent J. 2014;59 Suppl 1:101–16. Hughes TE, Townsend GC, Pinkerton SK, Bockmann MR, Seow WK, Brook AH, et al. The teeth and faces of twins: providing insights into dentofacial development and oral health for practising oral health professionals. Aust Dent J. 2014;59 Suppl 1:101–16.
2.
go back to reference Bretz WA, Corby PM, Schork NJ, Robinson MT, Coelho M, Costa S, et al. Longitudinal analysis of heritability for dental caries traits. J Dent Res. 2005;84(11):1047–51.CrossRefPubMed Bretz WA, Corby PM, Schork NJ, Robinson MT, Coelho M, Costa S, et al. Longitudinal analysis of heritability for dental caries traits. J Dent Res. 2005;84(11):1047–51.CrossRefPubMed
4.
go back to reference Fairpo CG. Total caries experience in monozygotic and like-sexed dizygotic twins of caucasoid origin aged 5 to 15 years. Arch Oral Biol. 1979;24(7):491–4.CrossRefPubMed Fairpo CG. Total caries experience in monozygotic and like-sexed dizygotic twins of caucasoid origin aged 5 to 15 years. Arch Oral Biol. 1979;24(7):491–4.CrossRefPubMed
5.
go back to reference Martins-Júnior PA, Ramos-Jorge ML, de Paiva SM, Pereira LJ, Marques LS. Premature deciduous tooth loss and orthodontic treatment need: a 6-year prospective study. J Public Health. 2017;25(2):173–9.CrossRef Martins-Júnior PA, Ramos-Jorge ML, de Paiva SM, Pereira LJ, Marques LS. Premature deciduous tooth loss and orthodontic treatment need: a 6-year prospective study. J Public Health. 2017;25(2):173–9.CrossRef
6.
go back to reference Wahl N. Orthodontics in 3 millennia. Chapter 1: Antiquity to the mid-19th century. Am J Orthod Dentofac Orthoped. 2005;127(2):255–9.CrossRef Wahl N. Orthodontics in 3 millennia. Chapter 1: Antiquity to the mid-19th century. Am J Orthod Dentofac Orthoped. 2005;127(2):255–9.CrossRef
7.
go back to reference Panchmal GS, Pullishery F, Siddique S, Ramaih VV, Shirodian V. Oral health related habits and oral hygiene practices in twins-A pilot study. J Med Dent Sci. 2015;14(5):61–4. Panchmal GS, Pullishery F, Siddique S, Ramaih VV, Shirodian V. Oral health related habits and oral hygiene practices in twins-A pilot study. J Med Dent Sci. 2015;14(5):61–4.
8.
go back to reference Rintakoski K, Hublin C, Lobbezoo F, Rose RJ, Kaprio J. Genetic factors account for half of the phenotypic variance in liability to sleep-related bruxism in young adults: a nationwide finnish twin cohort study. Twin Res Hum Genet. 2012;15(6):714–9.CrossRefPubMed Rintakoski K, Hublin C, Lobbezoo F, Rose RJ, Kaprio J. Genetic factors account for half of the phenotypic variance in liability to sleep-related bruxism in young adults: a nationwide finnish twin cohort study. Twin Res Hum Genet. 2012;15(6):714–9.CrossRefPubMed
9.
go back to reference Townsend GC, Richards L, Hughes T, Pinkerton S, Schwerdt W. The value of twins in dental research. Aust Dent J. 2003;48(2):82–8.CrossRefPubMed Townsend GC, Richards L, Hughes T, Pinkerton S, Schwerdt W. The value of twins in dental research. Aust Dent J. 2003;48(2):82–8.CrossRefPubMed
10.
go back to reference Sadeghi N, Gilmore JH, Gerig G. Twin-singleton developmental study of brain white matter anatomy. Hum Brain Mapp. 2017;38(2):1009–24.CrossRefPubMed Sadeghi N, Gilmore JH, Gerig G. Twin-singleton developmental study of brain white matter anatomy. Hum Brain Mapp. 2017;38(2):1009–24.CrossRefPubMed
11.
go back to reference Taşçıoğlu Y, Sayın C. Batı Akdeniz Bölgesi’nde Kırsal kalkınma yatırımlarını destekleme programı’ndan yararlanan işletmelerin destekleme programını kullanmalarını etkileyen faktörlerin belirlenmesi. TURJAF. 2017;5(7):786–91. Taşçıoğlu Y, Sayın C. Batı Akdeniz Bölgesi’nde Kırsal kalkınma yatırımlarını destekleme programı’ndan yararlanan işletmelerin destekleme programını kullanmalarını etkileyen faktörlerin belirlenmesi. TURJAF. 2017;5(7):786–91.
12.
go back to reference World Health Organization. Oral health surveys–basic methods. 4th ed. WHO press; 1997. World Health Organization. Oral health surveys–basic methods. 4th ed. WHO press; 1997.
13.
go back to reference Pinkham J. Pediatric dentistry: infancy through adolescence. 4th ed. MO: CV Mosby Co.; 2005. Pinkham J. Pediatric dentistry: infancy through adolescence. 4th ed. MO: CV Mosby Co.; 2005.
14.
go back to reference Andresen EM. Criteria for assessing the tools of disability outcomes research. Arch Phys Med Rehabil. 2000;81(12 Suppl 2):S15–20.CrossRefPubMed Andresen EM. Criteria for assessing the tools of disability outcomes research. Arch Phys Med Rehabil. 2000;81(12 Suppl 2):S15–20.CrossRefPubMed
15.
go back to reference Falconer DS. Introduction to Quantitive Genetics. 2nd ed. Longman; 1981. Falconer DS. Introduction to Quantitive Genetics. 2nd ed. Longman; 1981.
16.
go back to reference Kim E, Sung J, Song YM, Chae HS, Mo SS, Kim YH, et al. Heritability of facial skeletal and dental characteristics of monozygotic and dizygotic twins using cephalometric analysis and Falconer’s method. J Craniofac Surg. 2018;29(3):e274–9.CrossRefPubMed Kim E, Sung J, Song YM, Chae HS, Mo SS, Kim YH, et al. Heritability of facial skeletal and dental characteristics of monozygotic and dizygotic twins using cephalometric analysis and Falconer’s method. J Craniofac Surg. 2018;29(3):e274–9.CrossRefPubMed
17.
go back to reference Zarina R, Kuriakose S, Lalithamma J, D’Souza A, Padmakumari B, Jeeva P. Evaluation of inter-pair differences in caries among south Indian monozygotic twins: a cross-sectional study. Int J Clin Pediatr Dent. 2019;12(4):318–24.CrossRefPubMedPubMedCentral Zarina R, Kuriakose S, Lalithamma J, D’Souza A, Padmakumari B, Jeeva P. Evaluation of inter-pair differences in caries among south Indian monozygotic twins: a cross-sectional study. Int J Clin Pediatr Dent. 2019;12(4):318–24.CrossRefPubMedPubMedCentral
18.
go back to reference Wang X, Shaffer JR, Weyant RJ, Cuenco KT, DeSensi RS, Crout R, et al. Genes and their effects on dental caries may differ between primary and permanent dentitions. Caries Res. 2010;44(3):277–84.CrossRefPubMedPubMedCentral Wang X, Shaffer JR, Weyant RJ, Cuenco KT, DeSensi RS, Crout R, et al. Genes and their effects on dental caries may differ between primary and permanent dentitions. Caries Res. 2010;44(3):277–84.CrossRefPubMedPubMedCentral
19.
go back to reference AlQahtani SJ, Hector MP, Liversidge HM. Brief communication: the London atlas of human tooth development and eruption. Am J Phys Anthropol. 2010;142(3):481–90.CrossRefPubMed AlQahtani SJ, Hector MP, Liversidge HM. Brief communication: the London atlas of human tooth development and eruption. Am J Phys Anthropol. 2010;142(3):481–90.CrossRefPubMed
20.
21.
go back to reference Santana LG, Flores-Mir C, Iglesias-Linares A, Pithon MM, Marques LS. Influence of heritability on occlusal traits: a systematic review of studies in twins. Prog Orthod. 2020;21(1):1–11.CrossRef Santana LG, Flores-Mir C, Iglesias-Linares A, Pithon MM, Marques LS. Influence of heritability on occlusal traits: a systematic review of studies in twins. Prog Orthod. 2020;21(1):1–11.CrossRef
22.
go back to reference Hitos SF, Arakaki R, Solé D, Weckx LL. Oral breathing and speech disorders in children. J Pediatr. 2013;89(4):361–5.CrossRef Hitos SF, Arakaki R, Solé D, Weckx LL. Oral breathing and speech disorders in children. J Pediatr. 2013;89(4):361–5.CrossRef
23.
go back to reference Demircioğlu H, Yoldaş C. Çocukluk ve ergenlik döneminde psikososyal risk faktörleri ve koruyucu unsurlar. ASHD. 2019;18(1):40–8. Demircioğlu H, Yoldaş C. Çocukluk ve ergenlik döneminde psikososyal risk faktörleri ve koruyucu unsurlar. ASHD. 2019;18(1):40–8.
24.
go back to reference Boraas JC, Messer LB, Till MJ. A genetic contribution to dental caries, occlusion and morphology as demonstrated by twins reared apart. J Dent Res. 1988;67(9):1150–5.CrossRefPubMed Boraas JC, Messer LB, Till MJ. A genetic contribution to dental caries, occlusion and morphology as demonstrated by twins reared apart. J Dent Res. 1988;67(9):1150–5.CrossRefPubMed
25.
go back to reference Beltagy TM. Variance of occlusion among preschool monozygotic twins. Tanta Dent J. 2017;14(3):148–54.CrossRef Beltagy TM. Variance of occlusion among preschool monozygotic twins. Tanta Dent J. 2017;14(3):148–54.CrossRef
26.
go back to reference Mossey PA. The heritability of malocclusion: part 2. The influence of genetics in malocclusion. Br J Orthod. 1999;26(3):195–203.CrossRefPubMed Mossey PA. The heritability of malocclusion: part 2. The influence of genetics in malocclusion. Br J Orthod. 1999;26(3):195–203.CrossRefPubMed
27.
go back to reference Pellegrino M, Caruso S, Cantile T, Pellegrino G, Ferrazzano GF. Early treatment of anterior crossbite with eruption guidance appliance: a case report. Int J Environ Res Public Health. 2020;17(10):3587.CrossRefPubMedPubMedCentral Pellegrino M, Caruso S, Cantile T, Pellegrino G, Ferrazzano GF. Early treatment of anterior crossbite with eruption guidance appliance: a case report. Int J Environ Res Public Health. 2020;17(10):3587.CrossRefPubMedPubMedCentral
28.
go back to reference Corruccini RS, Potter RH. Genetic analysis of occlusal variation in twins. Am J Orthod. 1980;78(2):140–54.CrossRefPubMed Corruccini RS, Potter RH. Genetic analysis of occlusal variation in twins. Am J Orthod. 1980;78(2):140–54.CrossRefPubMed
29.
go back to reference Potter RH, Corruccini RS, Green LJ. Variance of occlusion traits in twins. J Craniofac Genet Dev Biol. 1981;1(2):217–27.PubMed Potter RH, Corruccini RS, Green LJ. Variance of occlusion traits in twins. J Craniofac Genet Dev Biol. 1981;1(2):217–27.PubMed
30.
go back to reference Townsend G, Hughes T, Luciano M, Bockmann M, Brook A. Genetic and environmental influences on human dental variation: a critical evaluation of studies involving twins. Arch Oral Biol. 2009;54(Suppl 1):S45–51.CrossRefPubMedPubMedCentral Townsend G, Hughes T, Luciano M, Bockmann M, Brook A. Genetic and environmental influences on human dental variation: a critical evaluation of studies involving twins. Arch Oral Biol. 2009;54(Suppl 1):S45–51.CrossRefPubMedPubMedCentral
Metadata
Title
The contribution of genetics to dental caries, oral habits and occlusal traits in Turkish twins: A comparative study
Authors
Esra Oz
Zuhal Kırzıoglu
Publication date
01-12-2023
Publisher
BioMed Central
Keyword
Bruxism
Published in
BMC Oral Health / Issue 1/2023
Electronic ISSN: 1472-6831
DOI
https://doi.org/10.1186/s12903-023-03426-9

Other articles of this Issue 1/2023

BMC Oral Health 1/2023 Go to the issue