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Critical Care
Published in: Critical Care 1/2020

Open Access 01-12-2020 | Bronchoscopy | Research Letter

SuPAR levels in BAL fluid from patients with acute respiratory distress syndrome—a pilot study

Authors: Alexander C. Reisinger, Gerald Hackl, Tobias Niedrist, Martin Hoenigl, Philipp Eller, Juergen Prattes

Published in: Critical Care | Issue 1/2020

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Excerpt

Blood levels of the soluble form of the urokinase plasminogen activator receptor (suPAR) predict mortality in patients with bacteremia and acute kidney injury [1, 2]; however, data on bronchoalveolar lavage fluid (BALF)-suPAR levels obtained from acute respiratory distress syndrome (ARDS) patients are missing. …
Literature
1.
Hayek SS, Leaf DE, Samman Tahhan A, Raad M, Sharma S, Waikar SS, Sever S, Camacho A, Wang X, Dande RR, et al. Soluble urokinase receptor and acute kidney injury. N Engl J Med. 2020;382(5):416–26.CrossRef
2.
Raggam RB, Wagner J, Pruller F, Grisold A, Leitner E, Zollner-Schwetz I, Valentin T, Krause R, Hoenigl M. Soluble urokinase plasminogen activator receptor predicts mortality in patients with systemic inflammatory response syndrome. J Intern Med. 2014;276(6):651–8.CrossRef
3.
Force ADT, Ranieri VM, Rubenfeld GD, Thompson BT, Ferguson ND, Caldwell E, Fan E, Camporota L, Slutsky AS. Acute respiratory distress syndrome: the Berlin Definition. JAMA. 2012;307(23):2526–33.
4.
Gussen H, Hohlstein P, Bartneck M, Warzecha KT, Buendgens L, Luedde T, Trautwein C, Koch A, Tacke F. Neutrophils are a main source of circulating suPAR predicting outcome in critical illness. J Intensive Care. 2019;7:26.CrossRef
Metadata
Title
SuPAR levels in BAL fluid from patients with acute respiratory distress syndrome—a pilot study
Authors
Alexander C. Reisinger
Gerald Hackl
Tobias Niedrist
Martin Hoenigl
Philipp Eller
Juergen Prattes
Publication date
01-12-2020
Publisher
BioMed Central
Published in
Critical Care / Issue 1/2020
Electronic ISSN: 1364-8535
DOI
https://doi.org/10.1186/s13054-020-03299-2

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