Skip to main content
Top
Published in: BMC Women's Health 1/2014

Open Access 01-12-2014 | Research article

Breast tuberculosis in Northeast Iran: review of 22 cases

Authors: Behnaz Khodabakhshi, Fatemeh Mehravar

Published in: BMC Women's Health | Issue 1/2014

Login to get access

Abstract

Background

Breast tuberculosis (breast TB) is an extremely rare disease, so case reviews are also rare.

Methods

This study is a retrospective review of patients with breast TB who were treated between 2002 and 2012 at the Health Center of Gorgan City.

Results

All 22 patients were females, their mean age was 32.4 years, and all were new cases. Patients presented with swelling of the breast (22%), lump (55%) and excretion from the involved breast (27%), and breast pain (55%). The highest rate of breast TB occurred in 2011 (27%). All patients received the DOTS regimen for a mean duration of 7.3 ± 0.7 months; in addition, segmental resection was performed on 11 patients (50%).

Conclusions

The findings confirmed that breast TB in Iran should be considered as a differential diagnosis of breast masses. All patients in our study received the daily and ‘Directly Observed Treatment Short-course’ (DOTS) regimens. Anti-tubercular therapy for six months with or without minimal surgical intervention currently is the main treatment.
Literature
1.
go back to reference Geneva: Global Tuberculosis Control: a Short Update to the 2012 Report. 2012, Geneva, Switzerland: World Health Organization Geneva: Global Tuberculosis Control: a Short Update to the 2012 Report. 2012, Geneva, Switzerland: World Health Organization
2.
go back to reference Cooper A: Illustration of the Diseases of the Breast. 1829, London: Longman, Rees, Orme, Brown, & Green Cooper A: Illustration of the Diseases of the Breast. 1829, London: Longman, Rees, Orme, Brown, & Green
3.
go back to reference Kaneria MVSP, Burkule D, Shukla A, Somani A, Nabar ST: Bilateral breast tuberculosis a rare entity. JIACM. 2006, 7: 61-63. Kaneria MVSP, Burkule D, Shukla A, Somani A, Nabar ST: Bilateral breast tuberculosis a rare entity. JIACM. 2006, 7: 61-63.
4.
go back to reference Tewari M, Shukla HS: Breast tuberculosis: diagnosis, clinical features & management. Indian J Med Res. 2005, 122 (2): 103-110.PubMed Tewari M, Shukla HS: Breast tuberculosis: diagnosis, clinical features & management. Indian J Med Res. 2005, 122 (2): 103-110.PubMed
5.
go back to reference Puneet SK, Tiwary RR, Sanjay Singh S: Breast tuberculosis: still common in India. Internet J Trop Med. 2005, 2 (2): 1540-2681. Puneet SK, Tiwary RR, Sanjay Singh S: Breast tuberculosis: still common in India. Internet J Trop Med. 2005, 2 (2): 1540-2681.
6.
go back to reference Sharma PK, Babel AL, Yadav SS: Tuberculosis of breast (study of 7 cases). J Postgrad Med. 1991, 37 (1): 24-26. 6APubMed Sharma PK, Babel AL, Yadav SS: Tuberculosis of breast (study of 7 cases). J Postgrad Med. 1991, 37 (1): 24-26. 6APubMed
7.
go back to reference Fadaei-Araghi M, Geranpayeh L, Irani S, Matloob R, Kuraki S: Breast tuberculosis: report of eight cases. Arch Iran Med. 2008, 11 (4): 463-465.PubMed Fadaei-Araghi M, Geranpayeh L, Irani S, Matloob R, Kuraki S: Breast tuberculosis: report of eight cases. Arch Iran Med. 2008, 11 (4): 463-465.PubMed
8.
go back to reference Banerjee SN, Ananthakrishnan N, Mehta RB, Parkash S: Tuberculous mastitis: a continuing problem. World J Surg. 1987, 11 (1): 105-109. 10.1007/BF01658471.CrossRefPubMed Banerjee SN, Ananthakrishnan N, Mehta RB, Parkash S: Tuberculous mastitis: a continuing problem. World J Surg. 1987, 11 (1): 105-109. 10.1007/BF01658471.CrossRefPubMed
9.
11.
go back to reference Martinez-Parra D, Nevado-Santos M, Melendez-Guerrero B, Garcia-Solano J, Hierro-Guilmain CC, Perez-Guillermo M: Utility of fine-needle aspiration in the diagnosis of granulomatous lesions of the breast. Diagn Cytopathol. 1997, 17 (2): 108-114. 10.1002/(SICI)1097-0339(199708)17:2<108::AID-DC5>3.0.CO;2-C.CrossRefPubMed Martinez-Parra D, Nevado-Santos M, Melendez-Guerrero B, Garcia-Solano J, Hierro-Guilmain CC, Perez-Guillermo M: Utility of fine-needle aspiration in the diagnosis of granulomatous lesions of the breast. Diagn Cytopathol. 1997, 17 (2): 108-114. 10.1002/(SICI)1097-0339(199708)17:2<108::AID-DC5>3.0.CO;2-C.CrossRefPubMed
12.
go back to reference Madhusudhan KS, Gamanagatti S: Primary breast tuberculosis masquerading as carcinoma. Singap Med J. 2008, 49 (1): e3-e5. Madhusudhan KS, Gamanagatti S: Primary breast tuberculosis masquerading as carcinoma. Singap Med J. 2008, 49 (1): e3-e5.
13.
go back to reference Wani I, Lone AM, Malik R, Wani KA, Wani RA, Hussain I, Thakur N, Snabel V: Secondary tuberculosis of breast: case report. ISRN Surgery. 2011, 2011: 529368.CrossRefPubMedPubMedCentral Wani I, Lone AM, Malik R, Wani KA, Wani RA, Hussain I, Thakur N, Snabel V: Secondary tuberculosis of breast: case report. ISRN Surgery. 2011, 2011: 529368.CrossRefPubMedPubMedCentral
14.
go back to reference Bhosale AA JA, Ashturkar AV, Pathak GS: Primary tuberculosis of breast: a case series. Ann Trop Med Public Health. 2012, 5 (3): 262-264. 10.4103/1755-6783.98634.CrossRef Bhosale AA JA, Ashturkar AV, Pathak GS: Primary tuberculosis of breast: a case series. Ann Trop Med Public Health. 2012, 5 (3): 262-264. 10.4103/1755-6783.98634.CrossRef
15.
go back to reference Luh SP, Chang KJ, Cheng JH, Hsu JD, Huang CS: Surgical treatment for primary mammary tuberculosis-report of three octogenarian cases and review of literature. Breast J. 2008, 14 (3): 311-312. 10.1111/j.1524-4741.2008.00584.x.CrossRefPubMed Luh SP, Chang KJ, Cheng JH, Hsu JD, Huang CS: Surgical treatment for primary mammary tuberculosis-report of three octogenarian cases and review of literature. Breast J. 2008, 14 (3): 311-312. 10.1111/j.1524-4741.2008.00584.x.CrossRefPubMed
16.
go back to reference Tanrikulu AC, Abakay A, Abakay O, Kapan M: Breast tuberculosis in Southeast Turkey: report of 27 cases. Breast Care (Basel). 2010, 5 (3): 154-157.CrossRef Tanrikulu AC, Abakay A, Abakay O, Kapan M: Breast tuberculosis in Southeast Turkey: report of 27 cases. Breast Care (Basel). 2010, 5 (3): 154-157.CrossRef
17.
go back to reference da Silva BB, Lopes-Costa PV, Pires CG, Pereira-Filho JD, dos Santos AR: Tuberculosis of the breast: analysis of 20 cases and a literature review. Trans R Soc Trop Med Hyg. 2009, 103 (6): 559-563. 10.1016/j.trstmh.2009.02.005.CrossRefPubMed da Silva BB, Lopes-Costa PV, Pires CG, Pereira-Filho JD, dos Santos AR: Tuberculosis of the breast: analysis of 20 cases and a literature review. Trans R Soc Trop Med Hyg. 2009, 103 (6): 559-563. 10.1016/j.trstmh.2009.02.005.CrossRefPubMed
18.
go back to reference Khanna R, Prasanna GV, Gupta P, Kumar M, Khanna S, Khanna AK: Mammary tuberculosis: report on 52 cases. Postgrad Med J. 2002, 78 (921): 422-424. 10.1136/pmj.78.921.422.CrossRefPubMedPubMedCentral Khanna R, Prasanna GV, Gupta P, Kumar M, Khanna S, Khanna AK: Mammary tuberculosis: report on 52 cases. Postgrad Med J. 2002, 78 (921): 422-424. 10.1136/pmj.78.921.422.CrossRefPubMedPubMedCentral
19.
go back to reference Harris SH, Khan MA, Khan R, Haque F, Syed A, Ansari MM: Mammary tuberculosis: analysis of thirty-eight patients. ANZ J Surg. 2006, 76 (4): 234-237. 10.1111/j.1445-2197.2006.03692.x.CrossRefPubMed Harris SH, Khan MA, Khan R, Haque F, Syed A, Ansari MM: Mammary tuberculosis: analysis of thirty-eight patients. ANZ J Surg. 2006, 76 (4): 234-237. 10.1111/j.1445-2197.2006.03692.x.CrossRefPubMed
20.
go back to reference Atamanalp SS, Gundogdu C, Polat P, Ozturk G, Ydinli B: Clinical presentation of breast tuberculosis in eastern Anatolia. Turk J Med Sci. 2010, 40 (2): 293-297. Atamanalp SS, Gundogdu C, Polat P, Ozturk G, Ydinli B: Clinical presentation of breast tuberculosis in eastern Anatolia. Turk J Med Sci. 2010, 40 (2): 293-297.
21.
go back to reference Kalac N, Ozkan B, Bayiz H, Dursun AB, Demirag F: Breast tuberculosis. Breast. 2002, 11 (4): 346-349. 10.1054/brst.2002.0420.CrossRefPubMed Kalac N, Ozkan B, Bayiz H, Dursun AB, Demirag F: Breast tuberculosis. Breast. 2002, 11 (4): 346-349. 10.1054/brst.2002.0420.CrossRefPubMed
22.
go back to reference Marinopoulos S, Lourantou D, Gatzionis T, Dimitrakakis C, Papaspyrou I, Antsaklis A: Breast tuberculosis: diagnosis, management and treatment. Int J Surg Investig Case Reports. 2012, 3 (11): 548-550. 10.1016/j.ijscr.2012.07.003.CrossRef Marinopoulos S, Lourantou D, Gatzionis T, Dimitrakakis C, Papaspyrou I, Antsaklis A: Breast tuberculosis: diagnosis, management and treatment. Int J Surg Investig Case Reports. 2012, 3 (11): 548-550. 10.1016/j.ijscr.2012.07.003.CrossRef
23.
go back to reference Bani-Hani KE, Yaghan RJ, Matalka II, Mazahreh TS: Tuberculous mastitis: a disease not to be forgotten. Int J Tuberc Lung Dis. 2005, 9 (8): 920-925.PubMed Bani-Hani KE, Yaghan RJ, Matalka II, Mazahreh TS: Tuberculous mastitis: a disease not to be forgotten. Int J Tuberc Lung Dis. 2005, 9 (8): 920-925.PubMed
24.
go back to reference Jalali U, Rasul S, Khan A, Baig N, Akhter R: Tuberculous mastitis. J Coll Physicians Surg Pak. 2005, 15 (4): 234-237.PubMed Jalali U, Rasul S, Khan A, Baig N, Akhter R: Tuberculous mastitis. J Coll Physicians Surg Pak. 2005, 15 (4): 234-237.PubMed
Metadata
Title
Breast tuberculosis in Northeast Iran: review of 22 cases
Authors
Behnaz Khodabakhshi
Fatemeh Mehravar
Publication date
01-12-2014
Publisher
BioMed Central
Published in
BMC Women's Health / Issue 1/2014
Electronic ISSN: 1472-6874
DOI
https://doi.org/10.1186/1472-6874-14-72

Other articles of this Issue 1/2014

BMC Women's Health 1/2014 Go to the issue