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05-01-2023 | Breast Cancer | Breast Oncology

Young Black Women May be More Likely to Have First Mammogram Cancers: A New Perspective in Breast Cancer Disparities

Authors: Avia D. Wilkerson, MD, Megan Obi, MD, Camila Ortega, MD, Audry Sebikali-Potts, BSN, RN, Wei Wei, MS, Holly J. Pederson, MD, Zahraa Al-Hilli, MD

Published in: Annals of Surgical Oncology | Issue 5/2023

Abstract

Introduction

Black women are diagnosed with breast cancer at earlier ages and are 42% more likely to die from the disease than White women. Recommendations for commencement of screening mammography remain discordant. This study sought to determine the frequency of first mammogram cancers among Black women versus other self-reported racial groups.

Methods

In this retrospective cohort study, clinical and mammographic data were obtained from 738 women aged 40–45 years who underwent treatment for breast cancer between 2010 and 2019 within a single hospital system. First mammogram cancers were defined as those with tissue diagnoses within 3 months of baseline mammogram. Multivariate logistic regression was applied to assess variables associated with first mammogram cancer detection.

Results

Black women were significantly more likely to have first mammogram cancer diagnoses (39/82, 47.6%) compared with White women (162/610, 26.6%) and other groups (16/46, 34.8%) [p < 0.001]. Black women were also more likely to have a body mass index > 30 (p < 0.001), higher clinical T categories (p = 0.02), and present with more advanced clinical stages (p = 0.03). Every month delay in mammographic screening beyond age 40 years (odds ratio [OR] 1.06, 95% confidence interval [CI] 1.05–1.07; p < 0.0001), Black race (OR 2.24, 95% CI 1.10–4.53; p = 0.03), and lack of private insurance (OR 2.41, 95% CI 1.22–4.73; p = 0.01) were associated with an increased likelihood of cancer detection on first mammogram.

Conclusion

Our findings suggests that Black women aged 40–45 years may be more likely to have cancer detected on their first mammogram and would benefit from starting screening mammography no later than age 40 years, and for those with elevated lifetime risk, even sooner.

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Title: Young Black Women May be More Likely to Have First Mammogram Cancers: A New Perspective in Breast Cancer Disparities
Authors: Avia D. Wilkerson, MD
Megan Obi, MD
Camila Ortega, MD
Audry Sebikali-Potts, BSN, RN
Wei Wei, MS
Holly J. Pederson, MD
Zahraa Al-Hilli, MD
Publication date: 05-01-2023
Publisher: Springer International Publishing
Keywords: Breast Cancer
Breast Cancer
Published in: Annals of Surgical Oncology / Issue 5/2023
Print ISSN: 1068-9265
Electronic ISSN: 1534-4681
DOI: https://doi.org/10.1245/s10434-022-12995-y

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Young Black Women May be More Likely to Have First Mammogram Cancers: A New Perspective in Breast Cancer Disparities

Abstract

Introduction

Methods

Results

Conclusion

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Abstract

Introduction

Methods

Results

Conclusion

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