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01-12-2013 | Review

Breakthroughs in research and treatment of early breast cancer: an overview of the last three decades

Authors: Manfred Kaufmann, Gunter von Minckwitz, Jonas Bergh, Pier-Franco Conte, Sarah Darby, Wolfgang Eiermann, Antony Howell, Marion Kiechle, Davide Mauri, Hans-Jörg Senn, Giuseppe Viale, Sibylle Loibl

Published in: Archives of Gynecology and Obstetrics | Issue 6/2013

Abstract

Breast cancer has become curable for the majority of women in Western Europe and North America. Advances have been made in imaging diagnostics as well as the implementation of nationwide screening programmes. Nowadays, we talk about prevention as well as treatment. Pathology has moved from pure morphology (tumour type, grade and stage) to biological characterisation of the tumour. Treatment has changed considerably through a better understanding of the disease; from a local disease predominated by extensive and mutilating surgical techniques to a point where breast cancer has come into its own as a systemic disease with equal “rights” to local as well as systemic treatment. This paradigm shift has led to a multidisciplinary approach of the understanding and treatment of breast cancer. Molecular classification has changed the understanding of breast cancer and will be the basis for an even more individualised treatment. New (biological) agents will help to further tailor treatment to response or resistance. While systemic treatment has been increased in number and duration surgical/local strategies have been reduced to minimum. Evidence-based medicine has helped to improve and standardise treatment of breast cancer. This review summarises the 10th Biedenkopf meeting that was held to review the advances in breast cancer understanding and treatment.

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Title: Breakthroughs in research and treatment of early breast cancer: an overview of the last three decades
Authors: Manfred Kaufmann
Gunter von Minckwitz
Jonas Bergh
Pier-Franco Conte
Sarah Darby
Wolfgang Eiermann
Antony Howell
Marion Kiechle
Davide Mauri
Hans-Jörg Senn
Giuseppe Viale
Sibylle Loibl
Publication date: 01-12-2013
Publisher: Springer Berlin Heidelberg
Published in: Archives of Gynecology and Obstetrics / Issue 6/2013
Print ISSN: 0932-0067
Electronic ISSN: 1432-0711
DOI: https://doi.org/10.1007/s00404-013-3069-4

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Breakthroughs in research and treatment of early breast cancer: an overview of the last three decades

Abstract

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Abstract

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