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BMC Public Health
Published in: BMC Public Health 1/2024

Open Access 01-12-2024 | Brain Tumor | Research

Maternal smoking, consumption of alcohol, and caffeinated beverages during pregnancy and the risk of childhood brain tumors: a meta-analysis of observational studies

Authors: Zihao Hu, Jianbo Ye, Shenbao Shi, Chuangcai Luo, Tianwei Wang, Yang Liu, Jing’an Ye, Xinlin Sun, Yiquan Ke, Chongxian Hou

Published in: BMC Public Health | Issue 1/2024

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Abstract

Background

We conducted this meta-analysis to investigate the potential association between maternal smoking, alcohol and caffeinated beverages consumption during pregnancy and the risk of childhood brain tumors (CBTs).

Methods

A thorough search was carried out on PubMed, Embase, Web of Science, Cochrane Library, and China National Knowledge Internet to identify pertinent articles. Fixed or random effects model was applied to meta-analyze the data.

Results

The results suggested a borderline statistically significant increased risk of CBTs associated with maternal smoking during pregnancy (OR 1.04, 95% CI 0.99–1.09). We found that passive smoking (OR 1.12, 95% CI 1.03–1.20), rather than active smoking (OR 1.00, 95% CI 0.93–1.07), led to an increased risk of CBTs. The results suggested a higher risk in 0–1 year old children (OR 1.21, 95% CI 0.94–1.56), followed by 0–4 years old children (OR 1.12, 95% CI 0.97–1.28) and 5–9 years old children (OR 1.11, 95% CI 0.95–1.29). This meta-analysis found no significant association between maternal alcohol consumption during pregnancy and CBTs risk (OR 1.00, 95% CI 0.80–1.24). An increased risk of CBTs was found to be associated with maternal consumption of caffeinated beverages (OR 1.16, 95% CI 1.07–1.26) during pregnancy, especially coffee (OR 1.18, 95% CI 1.00–1.38).

Conclusions

Maternal passive smoking, consumption of caffeinated beverages during pregnancy should be considered as risk factors for CBTs, especially glioma. More prospective cohort studies are warranted to provide a higher level of evidence.
Appendix
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Literature
1.
Steliarova-Foucher E, Colombet M, Ries LAG, Moreno F, Dolya A, Bray F, et al. International incidence of childhood cancer, 2001-10: a population-based registry study. Lancet Oncol. 2017;18(6):719–31.PubMedPubMedCentralCrossRef
2.
Rice JM, Ward JM. Age dependence of susceptibility to carcinogenesis in the nervous system. Ann N Y Acad Sci. 1982;381:274–89.PubMedCrossRef
3.
Chiavarini M, Naldini G, Fabiani R. Maternal folate intake and risk of Childhood Brain and spinal cord tumors: a systematic review and Meta-analysis. Neuroepidemiology. 2018;51(1–2):82–95.PubMedCrossRef
4.
Onyije FM, Dolatkhah R, Olsson A, Bouaoun L, Deltour I, Erdmann F, et al. Risk factors for childhood brain tumours: a systematic review and meta-analysis of observational studies from 1976 to 2022. Cancer Epidemiol. 2023;88:102510.PubMedCrossRef
5.
Organization WH. WHO global report on trends in prevalence of tobacco use 2000–2030 2024/01/16. 135 p.
6.
7.
Humans IWGotEoCRt. Personal habits and indoor combustions. IARC Monogr Eval Carcinog Risks Hum. 2012;100(Pt E):1–538.
8.
McKinney PA, Stiller CA, Dahlquist G, Wall S, Buckley JD, Hobbie WL, et al. Maternal smoking during pregnancy and the risk of childhood cancer. Lancet (London England). 1986;2(8505):519–20.CrossRef
9.
Stjernfeldt M, Berglund K, Lindsten J, Ludvigsson J. Maternal smoking during pregnancy and risk of childhood cancer. Lancet (London England). 1986;1(8494):1350–2.PubMedCrossRef
10.
Stjernfeldt M, Ludvigsson J, Berglund K, Lindsten J. Maternal smoking during pregnancy and the risk of childhood cancer. Lancet (London England). 1986;2(8508):687–8.PubMedCrossRef
11.
Howe GR, Burch JD, Chiarelli AM, Risch HA, Choi BC. An exploratory case-control study of brain tumors in children. Cancer Res. 1989;49(15):4349–52.PubMed
12.
Kuijten RR, Bunin GR, Nass CC, Meadows AT. Gestational and familial risk factors for childhood astrocytoma: results of a case-control study. Cancer Res. 1990;50(9):2608–12.PubMed
13.
John EM, Savitz DA, Sandler DP. Prenatal exposure to parents’ smoking and childhood cancer. Am J Epidemiol. 1991;133(2):123–32.PubMedCrossRef
14.
Gold EB, Leviton A, Lopez R, Gilles FH, Hedley-Whyte ET, Kolonel LN, et al. Parental smoking and risk of childhood brain tumors. Am J Epidemiol. 1993;137(6):620–8.PubMedCrossRef
15.
Bunin GR, Buckley JD, Boesel CP, Rorke LB, Meadows AT. Risk factors for astrocytic glioma and primitive neuroectodermal tumor of the brain in young children: a report from the children’s Cancer Group. Cancer Epidemiol Biomarkers Prev. 1994;3(3):197–204.PubMed
16.
Filippini G, Farinotti M, Lovicu G, Maisonneuve P, Boyle P. Mothers’ active and passive smoking during pregnancy and risk of brain tumours in children. Int J Cancer. 1994;57(6):769–74.PubMedCrossRef
17.
Norman MA, Holly EA, Ahn DK, Preston-Martin S, Mueller BA, Bracci PM. Prenatal exposure to tobacco smoke and childhood brain tumors: results from the United States West Coast childhood brain tumor study. Cancer Epidemiol Biomarkers Prev. 1996;5(2):127–33.PubMed
18.
Filippini G, Farinotti M, Ferrarini M. Active and passive smoking during pregnancy and risk of central nervous system tumours in children. Paediatr Perinat Epidemiol. 2000;14(1):78–84.PubMedCrossRef
19.
Hu J, Mao Y, Ugnat AM. Parental cigarette smoking, hard liquor consumption and the risk of childhood brain tumors–a case-control study in northeast China. Acta Oncol (Stockholm Sweden). 2000;39(8):979–84.CrossRef
20.
Schuz J, Kaletsch U, Kaatsch P, Meinert R, Michaelis J. Risk factors for pediatric tumors of the central nervous system: results from a German population-based case-control study. Med Pediatr Oncol. 2001;36(2):274–82.PubMedCrossRef
21.
Sorahan T, McKinney PA, Mann JR, Lancashire RJ, Stiller CA, Birch JM, et al. Childhood cancer and parental use of tobacco: findings from the inter-regional epidemiological study of childhood cancer (IRESCC). Br J Cancer. 2001;84(1):141–6.PubMedPubMedCentralCrossRef
22.
Filippini G, Maisonneuve P, McCredie M, Peris-Bonet R, Modan B, Preston-Martin S, et al. Relation of childhood brain tumors to exposure of parents and children to tobacco smoke: the SEARCH international case-control study. Surveillance of environmental aspects related to Cancer in humans. Int J Cancer. 2002;100(2):206–13.PubMedCrossRef
23.
Pang D, McNally R, Birch JM. Parental smoking and childhood cancer: results from the United Kingdom Childhood Cancer Study. Br J Cancer. 2003;88(3):373–81.PubMedPubMedCentralCrossRef
24.
Stavrou EP, Baker DF, Bishop JF. Maternal smoking during pregnancy and childhood cancer in New South Wales: a record linkage investigation. Cancer Causes Control. 2009;20(9):1551–8.PubMedCrossRef
25.
Milne E, Greenop KR, Scott RJ, Ashton LJ, Cohn RJ, de Klerk NH, et al. Parental smoking and risk of childhood brain tumors. Int J Cancer. 2012;133(1):253–9.CrossRef
26.
Heck JE, Contreras ZA, Park AS, Davidson TB, Cockburn M, Ritz B. Smoking in pregnancy and risk of cancer among young children: a population-based study. Int J Cancer. 2016;139(3):613–6.PubMedPubMedCentralCrossRef
27.
Tettamanti G, Ljung R, Mathiesen T, Schwartzbaum J, Feychting M. Maternal smoking during pregnancy and the risk of childhood brain tumors: results from a Swedish cohort study. Cancer Epidemiol. 2016;40:67–72.PubMedCrossRef
28.
Vienneau D, Infanger D, Feychting M, Schuz J, Schmidt LS, Poulsen AH, et al. A multinational case-control study on childhood brain tumours, anthropogenic factors, birth characteristics and prenatal exposures: a validation of interview data. Cancer Epidemiol. 2016;40:52–9.PubMedCrossRef
29.
Bailey HD, Lacour B, Guerrini-Rousseau L, Bertozzi AI, Leblond P, Faure-Conter C, et al. Parental smoking, maternal alcohol, coffee and tea consumption and the risk of childhood brain tumours: the ESTELLE and ESCALE studies (SFCE, France). Cancer Causes Control. 2017;28(7):719–32.PubMedCrossRef
30.
Neutel CI, Buck C. Effect of smoking during pregnancy on the risk of cancer in children. J Natl Cancer Inst. 1971;47(1):59–63.PubMed
31.
Pershagen G, Ericson A, Otterblad-Olausson P. Maternal smoking in pregnancy: does it increase the risk of childhood cancer? Int J Epidemiol. 1992;21(1):1–5.PubMedCrossRef
32.
McCredie M, Maisonneuve P, Boyle P. Antenatal risk factors for malignant brain tumours in New South Wales children. Int J Cancer. 1994;56(1):6–10.PubMedCrossRef
33.
Linet MS, Gridley G, Cnattingius S, Nicholson HS, Martinsson U, Glimelius B, et al. Maternal and perinatal risk factors for childhood brain tumors (Sweden). Cancer Causes Control. 1996;7(4):437–48.PubMedCrossRef
34.
35.
Schuz J, Kaatsch P, Kaletsch U, Meinert R, Michaelis J. Association of childhood cancer with factors related to pregnancy and birth. Int J Epidemiol. 1999;28(4):631–9.PubMedCrossRef
36.
Brooks DR, Mucci LA, Hatch EE, Cnattingius S. Maternal smoking during pregnancy and risk of brain tumors in the offspring. A prospective study of 1.4 million Swedish births. Cancer Causes Control. 2004;15(10):997–1005.PubMedCrossRef
37.
Pavlovic MV, Jarebinski MS, Pekmezovic TD, Janicijevic MA. Risk factors from brain tumors in children and adolescents: a case-control study in Belgrade, Serbia. Eur J Neurol. 2005;12(7):508–13.PubMedCrossRef
38.
Plichart M, Menegaux F, Lacour B, Hartmann O, Frappaz D, Doz F, et al. Parental smoking, maternal alcohol, coffee and tea consumption during pregnancy and childhood malignant central nervous system tumours: the ESCALE study (SFCE). Eur J Cancer Prev. 2008;17(4):376–83.PubMedPubMedCentralCrossRef
39.
Barrington-Trimis JL, Searles Nielsen S, Preston-Martin S, Gauderman WJ, Holly EA, Farin FM, et al. Parental smoking and risk of childhood brain tumors by functional polymorphisms in polycyclic aromatic hydrocarbon metabolism genes. PLoS ONE. 2013;8(11):e79110.PubMedPubMedCentralCrossRef
40.
Momen NC, Olsen J, Gissler M, Li J. Exposure to maternal smoking during pregnancy and risk of childhood cancer: a study using the Danish national registers. Cancer Causes Control. 2016;27(3):341–9.PubMedCrossRef
41.
Kessous R, Wainstock T, Sheiner E. Smoking during pregnancy as a possible risk factor for pediatric neoplasms in the offspring: a population-based cohort study. Addict Behav. 2019;90:349–53.PubMedCrossRef
42.
43.
Hou C, Hu Z, Ke Y. Maternal smoking and the risk of childhood brain tumors. Cancer Epidemiol. 2024;90:102547.PubMedCrossRef
44.
Onyije FM, Dolatkhah R, Olsson A, Bouaoun L, Deltour I, Erdmann F et al. Response to comments on: maternal smoking and the risk of childhood brain tumors. Cancer Epidemiol. 2024:102546.
45.
Rumgay H, Shield K, Charvat H, Ferrari P, Sornpaisarn B, Obot I, et al. Global burden of cancer in 2020 attributable to alcohol consumption: a population-based study. Lancet Oncol. 2021;22(8):1071–80.PubMedPubMedCentralCrossRef
46.
Rumgay H, Murphy N, Ferrari P, Soerjomataram I. Alcohol and Cancer: Epidemiology and Biological mechanisms. Nutrients. 2021;13(9).
47.
Deitrich R, Zimatkin S, Pronko S. Oxidation of ethanol in the brain and its consequences. Alcohol Res Health. 2006;29(4):266–73.PubMedPubMedCentral
48.
Corrao G, Bagnardi V, Zambon A, La Vecchia C. A meta-analysis of alcohol consumption and the risk of 15 diseases. Prev Med. 2004;38(5):613–9.PubMedCrossRef
49.
Birch JM, Hartley AL, Teare MD, Blair V, McKinney PA, Mann JR, et al. The inter-regional epidemiological study of childhood cancer (IRESCC): case-control study of children with central nervous system tumours. Br J Neurosurg. 1990;4(1):17–25.PubMedCrossRef
50.
Cordier S, Iglesias MJ, Le Goaster C, Guyot MM, Mandereau L, Hemon D. Incidence and risk factors for childhood brain tumors in the Ile De France. Int J Cancer. 1994;59(6):776–82.PubMedCrossRef
51.
Milne E, Greenop KR, Scott RJ, de Klerk NH, Bower C, Ashton LJ, et al. Parental alcohol consumption and risk of childhood acute lymphoblastic leukemia and brain tumors. Cancer Causes Control. 2013;24(2):391–402.PubMedCrossRef
52.
Georgakis MK, Dessypris N, Papadakis V, Tragiannidis A, Bouka E, Hatzipantelis E, et al. Perinatal and early life risk factors for childhood brain tumors: is instrument-assisted delivery associated with higher risk? Cancer Epidemiol. 2019;59:178–84.PubMedCrossRef
53.
Shin S, Lee JE, Loftfield E, Shu XO, Abe SK, Rahman MS, et al. Coffee and tea consumption and mortality from all causes, cardiovascular disease and cancer: a pooled analysis of prospective studies from the Asia Cohort Consortium. Int J Epidemiol. 2022;51(2):626–40.PubMedCrossRef
54.
Wu E, Bao YY, Wei GF, Wang W, Xu HQ, Chen JY, et al. Association of tea and coffee consumption with the risk of all-cause and cause-specific mortality among individuals with metabolic syndrome: a prospective cohort study. Diabetol Metab Syndr. 2023;15(1):241.PubMedPubMedCentralCrossRef
55.
Reyes CM, Cornelis MC. Caffeine in the Diet: Country-Level Consumption and Guidelines. Nutrients. 2018;10(11).
56.
Group CS. Maternal caffeine intake during pregnancy and risk of fetal growth restriction: a large prospective observational study. BMJ. 2008;337:a2332.CrossRef
57.
Qian J, Chen Q, Ward SM, Duan E, Zhang Y. Impacts of caffeine during pregnancy. Trends Endocrinol Metab. 2020;31(3):218–27.PubMedCrossRef
58.
Bunin GR, Kuijten RR, Boesel CP, Buckley JD, Meadows AT. Maternal diet and risk of astrocytic glioma in children: a report from the Childrens Cancer Group (United States and Canada). Cancer Causes Control. 1994;5(2):177–87.PubMedCrossRef
59.
Bunin GR, Kuijten RR, Buckley JD, Rorke LB, Meadows AT. Relation between maternal diet and subsequent primitive neuroectodermal brain tumors in young children. N Engl J Med. 1993;329(8):536–41.PubMedCrossRef
60.
Greenop KR, Miller M, Attia J, Ashton LJ, Cohn R, Armstrong BK, et al. Maternal consumption of coffee and tea during pregnancy and risk of childhood brain tumors: results from an Australian case-control study. Cancer Causes Control. 2014;25(10):1321–7.PubMedCrossRef
61.
Pogoda JM, Preston-Martin S, Howe G, Lubin F, Mueller BA, Holly EA, et al. An international case-control study of maternal diet during pregnancy and childhood brain tumor risk: a histology-specific analysis by food group. Ann Epidemiol. 2009;19(3):148–60.PubMedPubMedCentralCrossRef
62.
Page MJ, McKenzie JE, Bossuyt PM, Boutron I, Hoffmann TC, Mulrow CD, et al. The PRISMA 2020 statement: an updated guideline for reporting systematic reviews. BMJ. 2021;372:n71.PubMedPubMedCentralCrossRef
63.
Wells G, Shea B, O’Connell D, Peterson J, Welch V, Losos M et al. The Newcastle-Ottawa Scale (NOS) for assessing the quality of nonrandomised studies in meta-analyses. 2013.
64.
Greenland S. Quantitative methods in the review of epidemiologic literature. Epidemiol Rev. 1987;9:1–30.PubMedCrossRef
65.
66.
Higgins JP, Thompson SG. Quantifying heterogeneity in a meta-analysis. Stat Med. 2002;21(11):1539–58.PubMedCrossRef
67.
68.
69.
Wimberly C, Gulrajani N, Towry L, Landi D, Walsh K, editors. Maternal use of tobacco, alcohol, and illicit drugs during pregnancy and association with childhood cancer subtypes. 27 ed. Annual Scientific Meeting and Education Day Society for Neuro-Oncology’s; 2022. United States, Tampa Bay, FL.
70.
Chen C, Huang YB, Liu XO, Gao Y, Dai HJ, Song FJ, et al. Active and passive smoking with breast cancer risk for Chinese females: a systematic review and meta-analysis. Chin J Cancer. 2014;33(6):306–16.PubMedPubMedCentralCrossRef
71.
Lin Y, Kikuchi S, Tamakoshi K, Wakai K, Kondo T, Niwa Y, et al. Active smoking, passive smoking, and breast cancer risk: findings from the Japan Collaborative Cohort Study for evaluation of Cancer Risk. J Epidemiol. 2008;18(2):77–83.PubMedPubMedCentralCrossRef
72.
Dossus L, Boutron-Ruault MC, Kaaks R, Gram IT, Vilier A, Fervers B, et al. Active and passive cigarette smoking and breast cancer risk: results from the EPIC cohort. Int J Cancer. 2014;134(8):1871–88.PubMedCrossRef
73.
Lewandowska A, Rudzki G, Lewandowski T, Stryjkowska-Gora A, Rudzki S. Risk factors for the diagnosis of Colorectal Cancer. Cancer Control. 2022;29:10732748211056692.PubMedPubMedCentralCrossRef
74.
Arranz S, Chiva-Blanch G, Valderas-Martinez P, Medina-Remon A, Lamuela-Raventos RM, Estruch R. Wine, beer, alcohol and polyphenols on cardiovascular disease and cancer. Nutrients. 2012;4(7):759–81.PubMedPubMedCentralCrossRef
75.
Hrelia S, Di Renzo L, Bavaresco L, Bernardi E, Malaguti M, Giacosa A. Moderate Wine Consumption and Health: a narrative review. Nutrients. 2022;15(1).
76.
Gormley M, Dudding T, Sanderson E, Martin RM, Thomas S, Tyrrell J, et al. A multivariable mendelian randomization analysis investigating smoking and alcohol consumption in oral and oropharyngeal cancer. Nat Commun. 2020;11(1):6071.PubMedPubMedCentralCrossRef
77.
Hughes K, Bellis MA, Hardcastle KA, Sethi D, Butchart A, Mikton C, et al. The effect of multiple adverse childhood experiences on health: a systematic review and meta-analysis. Lancet Public Health. 2017;2(8):e356–66.PubMedCrossRef
78.
Alghamdi SS, Alshafi RA, Huwaizi S, Suliman RS, Mohammed AE, Alehaideb ZI, et al. Exploring in vitro and in silico Biological activities of Calligonum Comosum and Rumex Vesicarius: implications on Anticancer and Antibacterial therapeutics. Saudi Pharm J. 2023;31(11):101794.PubMedPubMedCentralCrossRef
79.
Ho B, Thompson A, Jorgensen AL, Pirmohamed M. Role of fatty liver index in risk-stratifying comorbid disease outcomes in non-alcoholic fatty liver disease. JHEP Rep. 2023;5(12):100896.PubMedPubMedCentralCrossRef
80.
Auvinen P, Vehvilainen J, Marjonen H, Modhukur V, Sokka J, Wallen E, et al. Chromatin modifier developmental pluripotency associated factor 4 (DPPA4) is a candidate gene for alcohol-induced developmental disorders. BMC Med. 2022;20(1):495.PubMedPubMedCentralCrossRef
81.
Malerba S, Galeone C, Pelucchi C, Turati F, Hashibe M, La Vecchia C, et al. A meta-analysis of coffee and tea consumption and the risk of glioma in adults. Cancer Causes Control. 2013;24(2):267–76.PubMedCrossRef
82.
Pranata R, Feraldho A, Lim MA, Henrina J, Vania R, Golden N, et al. Coffee and tea consumption and the risk of glioma: a systematic review and dose-response meta-analysis. Br J Nutr. 2022;127(1):78–86.PubMedCrossRef
83.
Song Y, Wang Z, Jin Y, Guo J. Association between tea and coffee consumption and brain cancer risk: an updated meta-analysis. World J Surg Oncol. 2019;17(1):51.PubMedPubMedCentralCrossRef
84.
Deweese JE, Osheroff N. The DNA cleavage reaction of topoisomerase II: wolf in sheep’s clothing. Nucleic Acids Res. 2009;37(3):738–48.PubMedCrossRef
85.
Ross JA, Potter JD, Reaman GH, Pendergrass TW, Robison LL. Maternal exposure to potential inhibitors of DNA topoisomerase II and infant leukemia (United States): a report from the children’s Cancer Group. Cancer Causes Control. 1996;7(6):581–90.PubMedCrossRef
86.
Grosso G, Godos J, Galvano F, Giovannucci EL. Coffee, Caffeine, and Health outcomes: an Umbrella Review. Annu Rev Nutr. 2017;37:131–56.PubMedCrossRef
87.
Oh CC, Jin A, Yuan JM, Koh WP. Coffee, tea, caffeine, and risk of nonmelanoma skin cancer in a Chinese population: the Singapore Chinese Health Study. J Am Acad Dermatol. 2019;81(2):395–402.PubMedPubMedCentralCrossRef
88.
Tamura T, Wada K, Konishi K, Goto Y, Mizuta F, Koda S, et al. Coffee, Green Tea, and Caffeine Intake and Liver Cancer risk: a prospective cohort study. Nutr Cancer. 2018;70(8):1210–6.PubMedCrossRef
89.
Cornelis MC, Munafo MR. Mendelian randomization studies of Coffee and Caffeine Consumption. Nutrients. 2018;10(10).
90.
Fagherazzi G, Touillaud MS, Boutron-Ruault MC, Clavel-Chapelon F, Romieu I. No association between coffee, tea or caffeine consumption and breast cancer risk in a prospective cohort study. Public Health Nutr. 2011;14(7):1315–20.PubMedCrossRef
91.
Ishitani K, Lin J, Manson JE, Buring JE, Zhang SM. Caffeine consumption and the risk of breast cancer in a large prospective cohort of women. Arch Intern Med. 2008;168(18):2022–31.PubMedPubMedCentralCrossRef
92.
Cnattingius S. The epidemiology of smoking during pregnancy: smoking prevalence, maternal characteristics, and pregnancy outcomes. Nicotine Tob Res. 2004;6(Suppl 2):S125–40.PubMedCrossRef
93.
Pickett KE, Wakschlag LS, Dai L, Leventhal BL. Fluctuations of maternal smoking during pregnancy. Obstet Gynecol. 2003;101(1):140–7.PubMed
Metadata
Title
Maternal smoking, consumption of alcohol, and caffeinated beverages during pregnancy and the risk of childhood brain tumors: a meta-analysis of observational studies
Authors
Zihao Hu
Jianbo Ye
Shenbao Shi
Chuangcai Luo
Tianwei Wang
Yang Liu
Jing’an Ye
Xinlin Sun
Yiquan Ke
Chongxian Hou
Publication date
01-12-2024
Publisher
BioMed Central
Published in
BMC Public Health / Issue 1/2024
Electronic ISSN: 1471-2458
DOI
https://doi.org/10.1186/s12889-024-18569-9

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