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Annals of Surgical Oncology
Published in: Annals of Surgical Oncology 1/2013

01-01-2013 | Endocrine Tumors

BRAF V600E Mutation Independently Predicts Central Compartment Lymph Node Metastasis in Patients with Papillary Thyroid Cancer

Authors: Martha A. Zeiger, MD, FACS, Eric B. Schneider, PhD

Published in: Annals of Surgical Oncology | Issue 1/2013

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Excerpt

Howell et al. examine a very timely question regarding the utility of measuring BRAF mutation status in papillary thyroid cancer (PTC) specimens to determine if it can be used to predict the presence or absence of lymph node metastases. The premise is that its measurement could potentially guide the surgical management of patients with PTC; i.e., to determine whether a prophylactic central lymph node dissection (CLND) should be performed. This is a very well-written study that nicely captures the common clinical dilemma faced by endocrine surgeons and also is comprehensive in the interpretation of its results. …
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Metadata
Title
BRAF V600E Mutation Independently Predicts Central Compartment Lymph Node Metastasis in Patients with Papillary Thyroid Cancer
Authors
Martha A. Zeiger, MD, FACS
Eric B. Schneider, PhD
Publication date
01-01-2013
Publisher
Springer-Verlag
Published in
Annals of Surgical Oncology / Issue 1/2013
Print ISSN: 1068-9265
Electronic ISSN: 1534-4681
DOI
https://doi.org/10.1245/s10434-012-2614-x

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