Top

Current Psychiatry Reports

Published in:

03-10-2023 | Borderline Personality Disorder

The Co-occurrence of Personality Disorders and Substance Use Disorders

Authors: Khrystyna Stetsiv, Ian A. McNamara, Melissa Nance, Ryan W. Carpenter

Published in: Current Psychiatry Reports | Issue 11/2023

Abstract

Purpose of Review

Despite significant negative outcomes, the co-occurrence of personality disorders (PDs) and substance use disorders (SUDs) continues to be underrecognized, and the mechanisms contributing to this co-occurrence remain unclear. This review summarizes recent work on PD-SUD co-occurrence, with a focus on borderline and antisocial PDs, general substance use patterns among those with PDs, and the association of personality traits with SUDs.

Recent Findings

The prevalence of co-occurring PD-SUD is generally high, with estimates ranging depending on the type of PD and SUD, the population assessed, and the sampling methods and measures used. Current theoretical explanations for co-occurrence include shared etiology and predisposition models, with research highlighting the importance of transactional processes. Potential underlying mechanisms include personality traits and transdiagnostic characteristics.

Summary

Recent research has increased focus on substances besides alcohol, dimensional models of personality pathology, and transactional explanations of co-occurrence, but more research is needed to disentangle the nuanced PD-SUD relationship.

•• Helle AC, Watts AL, Trull TJ, Sher KJ. Alcohol use disorder and antisocial and borderline personality disorders. Alcohol Res Curr Rev. 2019;40:35–50. Review of co-occurring alcohol use disorder and antisocial and borderline personality disorders, with an emphasis on theoretical explanations, outcomes, and treatments.

Kienast T, Stoffers J, Bermpohl F, Lieb K. Borderline personality disorder and comorbid addiction. Dtsch Arztebl Int. 2014;111(16):280–6.PubMedPubMedCentral

Parmar A, Kaloiya G. Comorbidity of personality disorder among substance use disorder patients: a narrative review. Indian J Psychol Med. 2018;40(6):517–27.PubMedPubMedCentralCrossRef

American Psychiatric Association. Diagnostic and statistical manual of mental disorders: DSM-5. [Internet]. 5th edition. Arlington, VA: American Psychiatric Association; 2013 [cited 2023 Jun 21]. 947 p.

Trull TJ, Jahng S, Tomko RL, Wood PK, Sher KJ. Revised NESARC personality disorder diagnoses: gender, prevalence, and comorbidity with substance dependence disorders. J Pers Disord. 2010;24(4):412–26.PubMedPubMedCentralCrossRef

Substance Abuse and Mental Health Services Administration (SAMHSA). 2021 NSDUH Annual National Report | CBHSQ Data [Internet]. 2021 [cited 2023 Jun 22]. Available from: https://www.samhsa.gov/data/report/2021-nsduh-annual-national-report

Guy N, Newton-Howes G, Ford H, Williman J, Foulds J. The prevalence of comorbid alcohol use disorder in the presence of personality disorder: systematic review and explanatory modelling. Personal Ment Health. 2018;12(3):216–28.PubMedCrossRef

Kuo CJ, Chen WY, Tsai SY, Chen PH, Ko KT, Chen CC. Excessive mortality and causes of death among patients with personality disorder with comorbid psychiatric disorders. Soc Psychiatry Psychiatr Epidemiol. 2019;54(1):121–30.PubMedCrossRef

• Hanna Chaim C, Santana GL, de Vries Albertin P, Silveira CM, Siu ER, Viana MC, et al. Alcohol use patterns and disorders among individuals with personality disorders in the Sao Paulo Metropolitan Area. PLoS One. 2021;16(3):e0248403. Cross-sectional study of prevalence of alcohol use disorder and patterns among 2942 Brazilian adults in Brazil, which found Cluster B PDs to be particularly associated with alcohol.

10.

González E, Arias F, Szerman N, Vega P, Mesias B, Basurte I. Coexistence between personality disorders and substance use disorder. Madrid study about prevalence of dual pathology. Actas Esp Psiquiatr. 2019;47(6):218–28.

11.

Trull TJ, Freeman LK, Vebares TJ, Choate AM, Helle AC, Wycoff AM. Borderline personality disorder and substance use disorders: an updated review. Borderline Personality Disord Emot Dysregulation. 2018;5(1):15.PubMedPubMedCentralCrossRef

12.

Sher L, Rutter SB, New AS, Siever LJ, Hazlett EA. Gender differences and similarities in aggression, suicidal behaviour, and psychiatric comorbidity in borderline personality disorder. Acta Psychiatr Scand. 2019;139(2):145–53.PubMedCrossRef

13.

Scalzo F, Hulbert CA, Betts JK, Cotton SM, Chanen AM. Substance use in youth with borderline personality disorder. J Pers Disord. 2018;32(5):603–17.PubMedCrossRef

14.

Scalzo F, Hulbert CA, Betts JK, Cotton SM, Chanen AM. Predictors of substance use in youth with borderline personality disorder. Personal Disord. 2018;9(4):390–6.PubMedCrossRef

15.

Howard R, Hasin D, Stohl M. Substance use disorders and criminal justice contact among those with co-occurring antisocial and borderline personality disorders: findings from a nationally representative sample. Personal Ment Health. 2021;15(1):40–8.PubMedCrossRef

16.

Mundt AP, Baranyi G. The unhappy mental health triad: comorbid severe mental illnesses, personality disorders, and substance use disorders in prison populations. Front Psychiatry. 2020;11:804.PubMedPubMedCentralCrossRef

17.

Holzer KJ, Vaughn MG, Loux TM, Mancini MA, Fearn NE, Wallace CL. Prevalence and correlates of antisocial personality disorder in older adults. Aging Ment Health. 2022;26(1):169–78.PubMedCrossRef

18.

Puddephatt JA, Jones A, Gage SH, Fear NT, Field M, McManus S, et al. Associations of alcohol use, mental health and socioeconomic status in England: findings from a representative population survey. Drug Alcohol Depend. 2021;1(219): 108463.CrossRef

19.

Torgersen S, Kringlen E, Cramer V. The prevalence of personality disorders in a community sample. Arch Gen Psychiatry. 2001;58(6):590–6.PubMedCrossRef

20.

Hochheimer M, Sacco P, Ware OD. Latent classes of lifetime drug use disorder in national epidemiological survey on alcohol and related conditions - III. Addict Behav. 2020;106: 106379.PubMedCrossRef

21.

Carpenter RW, Wood PK, Trull TJ. Comorbidity of borderline personality disorder and lifetime substance use disorders in a nationally representative sample. J Pers Disord. 2016;30(3):336–50.PubMedCrossRef

22.

Rhee TG, Rosenheck RA. Gender differences in psychiatric and behavioral health burden among adults with alcohol and other substance use disorders in the United States. J Addict Med. 2022;16(3):295–302.PubMedCrossRef

23.

Cavicchioli M, Prudenziati F, Movalli M, Ramella P, Maffei C. The severity of personality pathology: a risk factor for concurrent substance use disorders in alcohol use disorder. J Dual Diagn. 2019;15(3):159–71.PubMedCrossRef

24.

Zhang C, Luo T, Liu L, Dong H, Hao W. Prevalence rates of personality disorder and its association with methamphetamine dependence in compulsory treatment facilities in China. Front Psychiatry. 2018;9:698.PubMedPubMedCentralCrossRef

25.

Ma CH, Lin KF, Chen TT, Yu YF, Chien HF, Huang WL. Specific personality traits and associated psychosocial distresses among individuals with heroin or methamphetamine use disorder in Taiwan. J Formos Med Assoc. 2020;119(3):735–42.PubMedCrossRef

26.

Loya JM, Tangney JP, Stuewig JB. Are borderline personality disorder features differentially related to pre-incarceration alcohol, cannabis, cocaine, and opioid dependence among people recently incarcerated in jail? J Pers Disord. 2022;36(5):623–40.PubMedCrossRef

27.

Sharma P, Riehm KE, Young AS, Reynolds MD, Tarter RE, Horner MS, et al. Do the transmissible liability index (TLI) and adolescent cannabis use predict paranoid and schizotypal symptoms at young adulthood? Subst Use Misuse. 2021;56(13):2026–34.PubMedCrossRef

28.

Bronchain J, Chabrol H, Raynal P. Could schizotypy protect against the negative outcomes of borderline traits on alcohol consumption? A cluster analytic study Psychiatry Res. 2018;269:21–4.PubMed

29.

Gillespie NA, Aggen SH, Neale MC, Knudsen GP, Krueger RF, South SC, et al. Associations between personality disorders and cannabis use and cannabis use disorder: a population-based twin study. Addiction. 2018;113(8):1488–98.PubMedPubMedCentralCrossRef

30.

Spencer M, Miniño A, Warner M. Drug overdose deaths in the United States, 2001–2021. NCHS Data Brief, no 457. [Internet]. Hyattsville, MD: Nat Center Health Stat.; 2022 [cited 2023 Jun 22]. https://www.cdc.gov/nchs/products/databriefs/db457.htm.

31.

Santo TJ, Campbell G, Gisev N, Martino-Burke D, Wilson J, Colledge-Frisby S, et al. Prevalence of mental disorders among people with opioid use disorder: a systematic review and meta-analysis. Drug Alcohol Depend. 2022;1(238): 109551.CrossRef

32.

Klimas J, Gorfinkel L, Fairbairn N, Amato L, Ahamad K, Nolan S, et al. Strategies to identify patient risks of prescription opioid addiction when initiating opioids for pain: a systematic review. JAMA Netw Open. 2019;2(5): e193365.PubMedPubMedCentralCrossRef

33.

Farooqui AM, Arya A, Singh A, Dalal PK. Psychiatric comorbidity, psychosocial problems, and functioning of people who inject opioids: an observational study. Addict Health. 2022;14(3):218–23.PubMedPubMedCentralCrossRef

34.

Nevid JS, Gordon AJ, Barris A, Sperber JE, Haggerty G. Personality profiles of patients with alcohol use disorder and opioid use disorder in an inpatient treatment setting. J Subst Abuse Treat. 2019;97:91–6.PubMedCrossRef

35.

Nichols LM, Pedroza JA, Fleming CM, O’Brien KM, Tanner-Smith EE. Social-ecological predictors of opioid use among adolescents with histories of substance use disorders. Front Psychol. 2021;12: 686414.PubMedPubMedCentralCrossRef

36.

Vest N, Tragesser S. Borderline features and prescription opioid misuse in a substance use disorder treatment sample. Subst Use Misuse. 2019;54(1):166–75.PubMedCrossRef

37.

Bhalla IP, Stefanovics EA, Rosenheck RA. Clinical epidemiology of single versus multiple substance use disorders: polysubstance use disorder. Med Care. 2017;55(9):S24-32.PubMedCrossRef

38.

Dash GF, Martin NG, Agrawal A, Lynskey MT, Slutske WS. Typologies of illicit drug use in mid-adulthood: a quasi-longitudinal latent class analysis in a community-based sample of twins. Addiction. 2021;116(5):1101–12.PubMedCrossRef

39.

• Cougle JR, McDermott KA, Hakes JK, Joyner KJ. Personality disorders and social support in cannabis dependence: a comparison with alcohol dependence. J Affect Disord. 2020;265:26–31. Cross-sectional study using NESARC, which found that people with both alcohol and cannabis dependence had higher rates of PDs and a greater number of PDs than those with either diagnosis alone.

40.

Ellis JD, Pittman BP, McKee SA. Co-occurring opioid and sedative use disorder: gender differences in use patterns and psychiatric co-morbidities in the United States. J Subst Abuse Treat. 2020;114: 108012.PubMedPubMedCentralCrossRef

41.

Trull TJ, Durrett CA. Categorical and dimensional models of personality disorder. Annu Rev Clin Psychol. 2005;1:355–80.PubMedCrossRef

42.

Guillot CR, Lucke HR, Ramsey AJ, Kearns NT, Blumenthal H, Berman ME. Cluster-b personality disorder traits and impulsivity: indirect associations with alcohol use severity through positive alcohol expectancies. Exp Clin Psychopharmacol. 2022.

43.

Poelen EAP, Schijven EP, Otten R. The mediating role of substance use motives in the relationship between personality dimensions and alcohol and drug use in adolescents and young adults with mild intellectual disabilities. Addict Behav. 2022;126: 107173.PubMedCrossRef

44.

Roviš D, Vasiljev V, Jenko-Pražnikar Z, Petelin A, Drevenšek G, Peruč D, et al. Mental health and drug use severity: the role of substance P, neuropeptide Y, self-reported childhood history of trauma, parental bonding and current resiliency. J Ment Health. 2021;30(1):88–96.PubMedCrossRef

45.

• Moraleda E, Ramírez López J, Fernández-Calderón F, Lozano ÓM, Diaz-Batanero C. Personality traits among the various profiles of substance use disorder patients: new evidence using the DSM-5 Section III framework. Eur Addict Res. 2019;25(5):238–47. Cross-sectional study assessing relationships between facets of the Alternative Model for Personality Disorders, substance use disorders, and substance use profiles among a sample of patients in SUD treatment.

46.

Bresin K, Mekawi Y, Stevens JS, Hinrichs R, Fani N, Michopoulos V, et al. From alcohol to aggression: examining the structure and nomological network of dysregulated behaviors in a trauma-exposed community sample. J Clin Psychol. 2022;78(6):1220–39.PubMedCrossRef

47.

• De la Rosa-Cáceres A, Narvaez-Camargo M, Blanc-Molina A, Romero-Pérez N, Dacosta-Sánchez D, González-Ponce BM, et al. Bridge nodes between personality traits and alcohol-use disorder criteria: the relevance of externalizing traits of risk taking, callousness, and irresponsibility. J Clin Med. 2022;11(12). Cross-sectional study with an adult sample in Spain, which linked several externalizing AMPD facets with AUD criteria.

48.

• Choate AM, Gorey C, Rappaport LM, Wiernik BM, Bornovalova MA. Alternative model of personality disorders traits predict residential addictions treatment completion. Drug Alcohol Depend. 2021;228:109011. A study linking AMPD facets with premature treatment termination in a cross-sectional sample of people receiving residential SUD treatment.

49.

•• Krueger RF, Hobbs KA, Conway CC, Dick DM, Dretsch MN, Eaton NR, et al. Validity and utility of Hierarchical Taxonomy of Psychopathology (HiTOP): II. Externalizing superspectrum. World Psych. 2021;20(2):171–93. Review of evidence on the validity and utility of the externalizing spectrum of the Hierarchical Taxonomy of Psychopathology.

50.

Ignatyev Y, Baggio S, Mundt AP. The underlying structure of comorbid mental health and substance use disorders in prison populations. Psychopathology. 2019;52(1):2–9.PubMedCrossRef

51.

McDonald JB, Bozzay ML, Bresin K, Verona E. Facets of externalizing psychopathology in relation to inhibitory control and error processing. Int J Psychophysiol. 2021;163:79–91.PubMedCrossRef

52.

McDowell YE, Vergés A, Sher KJ. Are some alcohol use disorder criteria more (or less) externalizing than others? Distinguishing alcohol use symptomatology from general externalizing psychopathology. Alcohol Clin Exp Res. 2019;43(3):483–96.PubMedPubMedCentralCrossRef

53.

Bailey AJ, Finn PR. Borderline personality disorder symptom comorbidity within a high externalizing sample: relationship to the internalizing-externalizing dimensional structure of psychopathology. J Pers Disord. 2020;34(6):814–26.PubMedCrossRef

54.

• Watts AL, Watson D, Heath AC, Sher KJ. Alcohol use disorder criteria exhibit different comorbidity patterns. Addiction [Internet]. [cited 2023];n/a(n/a). https://doi.org/10.1111/add.1612. Study mapping individual AUD criteria onto internalizing and externalizing dimensions, using multivariate and factor analytical modeling in two large nationally representative samples of past-year drinkers.

55.

• Watts AL, Latzman RD, Boness CL, Kotov R, Keyser-Marcus L, DeYoung CG et al. New approaches to deep phenotyping in addictions. Psychol Addict Behav. 2023;37(3):361–75. Review and integration of two recently developed frameworks (NIDA PhAB and HiTOP) utilizing deep phenotyping to improve the understanding of causes and consequences of psychopathology.

56.

•• Rosenström T, Torvik FA, Ystrom E, Aggen SH, Gillespie NA, Krueger RF et al. Specific antisocial and borderline personality disorder criteria and general substance use: a twin study. Personal Disord. 2021;12(3):228–40. Longitudinal study using a sample of 1410 pairs of Norwegian twins, which showed that a general factor encompassing ASPD and BPD criteria was related to general substance use.

57.

Bonifay W, Lane SP, Reise SP. Three concerns with applying a bifactor model as a structure of psychopathology. Clinical Psychological Science. 2017;5(1):184–6.CrossRef

58.

Kaufman EA, Perez J, Lazarus S, Stepp SD, Pedersen SL. Understanding the association between borderline personality disorder and alcohol-related problems: an examination of drinking motives, impulsivity, and affective instability. Personal Disord. 2020;11(3):213–21.PubMedCrossRef

59.

• Scamaldo KM, Tull MT, Gratz KL. Motives for opioid use explain the relation between borderline personality disorder pathology and opioid use problems. Psychiatry Res. 2021;296:113609. Cross-sectional study showing the importance of both emotion- and interpersonal-related motives for opioid use among patients with BPD pathology in SUD treatment.

60.

Vest NA, Murphy KT, Tragesser SL. Borderline personality disorder features and drinking, cannabis, and prescription opioid motives: differential associations across substance and sex. Addict Behav. 2018;87:46–54.PubMedCrossRef

61.

Miglin R, Bounoua N, Spielberg JM, Sadeh N. A transdiagnostic examination of affective motivations for drug use. Addict Behav Rep. 2020;12: 100279.PubMedPubMedCentral

62.

• Vest NA, Tragesser S. Coping motives mediate the relationship between borderline personality features and alcohol, cannabis, and prescription opioid use disorder symptomatology in a substance use disorder treatment sample. Personal Disord. 2020;11(3):230–6. Cross-sectional study using a sample of 193 individuals in SUD treatment, which showed the role of coping motives in the relationships between BPD and alcohol, cannabis, and opioid use disorders.

63.

• Chugani CD, Byrd AL, Pedersen SL, Chung T, Hipwell AE, Stepp SD. Affective and sensation-seeking pathways linking borderline personality disorder symptoms and alcohol-related problems in young women. J Pers Disord. 2020;34(3):420–31. Cross-sectional study highlighting coping and enhancement drinking motives as possible mechanisms that explain co-occurrence of BPD symptoms and alcohol-related problems in young females.

64.

• Wycoff AM, Carpenter RW, Hepp J, Lane SP, Trull TJ. Drinking motives moderate daily-life associations between affect and alcohol use in individuals with borderline personality disorder. Psychol Addict Behav. 2020;34(7):745–55. Ecological momentary assessment study examining daily drinking motives, affect, and alcohol use in a BPD sample.

65.

Mackesy-Amiti ME, Donenberg G. Negative affect and emotion dysregulation among people who inject drugs: an ecological momentary assessment study. Psychol Addict Behav. 2020;34(6):650–9.PubMedPubMedCentralCrossRef

66.

Neale MC, Kendler KS. Models of comorbidity for multifactorial disorders. Am J Hum Genet. 1995;57(4):935–53.PubMedPubMedCentral

67.

Acheson A, Vincent AS, Cohoon AJ, Lovallo WR. Early life adversity and increased antisocial and depressive tendencies in young adults with family histories of alcohol and other substance use disorders: findings from the Family Health Patterns project. Addict Behav Rep. 2022;15: 100401.PubMed

68.

Feder KA, Ali MM, Sherman LJ, Letourneau E, Barry CL, Stuart EA, et al. Elevated prevalence of antisocial behavior in adolescent children whose mothers misuse opioids. Drug Alcohol Depend. 2020;1(215): 108153.CrossRef

69.

• Scholes-Balog KE, Hemphill SA, Heerde JA, Toumbourou JW, Patton GC. Childhood social environmental and behavioural predictors of early adolescent onset cannabis use. Drug Alcohol Rev. 2020;39(4):384–93. Longitudinal study showing the associations between family history of antisocial behavior and early adolescent onset cannabis use.

70.

Kerr S, Dalrymple K, Chelminski I, Zimmerman M. Depression and substance use disorders in the offspring of depressed parents as a function of the parent’s borderline personality disorder symptomatology. Ann Clin Psychiatry. 2018;30(2):207–14.PubMed

71.

•• Rosenström T, Czajkowski NO, Ystrom E, Krueger RF, Aggen SH, Gillespie NA, et al. Genetically informative mediation modeling applied to stressors and personality-disorder traits in etiology of alcohol use disorder. Behav Genet. 2019;49(1):11–23. Longitudinal study using a sample of 1410 pairs of Norwegian twins, which found that adulthood antisocial and impulsive traits mediated the effect of childhood stressful life events on adulthood AUD.

72.

Sher KJ, Trull TJ. Substance use disorder and personality disorder. Curr Psychiatry Rep. 2002;4(1):25–9.PubMedCrossRef

73.

Trull TJ, Sher KJ, Minks-Brown C, Durbin J, Burr R. Borderline personality disorder and substance use disorders: a review and integration. Clin Psychol Rev. 2000;20(2):235–53.PubMedCrossRef

74.

Snow MB, Balling C, Zimmerman M. Re-examining borderline personality disorder and substance use disorder: the role of emotion dysregulation. Ann Clin Psychiatry. 2020;32(3):170–5.PubMed

75.

Boog M, Dugonjic H, Arntz A, Goudriaan AE, Wetering BJMVD, Franken IHA. Borderline personality disorder with versus without alcohol use disorder: comparing impulsivity and schema modes. J Pers Disord. 2022;36(1):1–18.

76.

• Moraleda-Barreno E, Cáceres Pachón MDP, Lozano ÓM, Pérez Moreno PJ, Lorca Marín JA, Fernández-Calderón F, et al. Impairments in executive functioning in patients with comorbid substance use and personality disorders: a systematic review. J Dual Diagn. 2021;17(1):64–79. Review on impairments in executive functioning in people with comorbid substance use and Cluster A, B, and C personality disorders, compared to those with a single diagnosis.

77.

Griffin SA, Freeman LK, Trull TJ. Measuring impulsivity in daily life: a systematic review and recommendations for future research [Internet]. PsyArXiv; 2020 [cited 2023 Jun 30]. Available from: https://psyarxiv.com/mfdp6/

78.

• Defoe IN, Khurana A, Betancourt LM, Hurt H, Romer D. Cascades from early adolescent impulsivity to late adolescent antisocial personality disorder and alcohol use disorder. J Adolesc Health. 2022;71(5):579–86. Longitudinal study using mediation to show associations between early adolescent impulsivity, mid-adolescent alcohol use and conduct problems, and late adolescent ASPD and AUD.

79.

da Silva BS, Cupertino RB, Schuch JB, Kappel DB, Sanvicente-Vieira B, Bandeira CE, et al. The association between SYT1-rs2251214 and cocaine use disorder further supports its role in psychiatry. Prog Neuropsychopharmacol Biol Psychiatry. 2019;30(94): 109642.CrossRef

80.

Karlsson Linnér R, Mallard TT, Barr PB, Sanchez-Roige S, Madole JW, Driver MN, et al. Multivariate analysis of 1.5 million people identifies genetic associations with traits related to self-regulation and addiction. Nat Neurosci. 2021;24(10):1367–76.

81.

Ruocco AC, Daros AR, Chang J, Rodrigo AH, Lam J, Ledochowski J, et al. Clinical, personality, and neurodevelopmental phenotypes in borderline personality disorder: a family study. Psychol Med. 2019;49(12):2069–80.PubMedCrossRef

82.

•• Hanegraaf L, van Baal S, Hohwy J, Verdejo-Garcia A. A systematic review and meta-analysis of “Systems for Social Processes” in borderline personality and substance use disorders. Neurosci Biobehav Rev. 2021;127:572–92. Review and meta-analysis showing that deficits in social processing may be a core transdiagnostic phenotype of BPD and SUD.

83.

•• Mattingley S, Youssef GJ, Manning V, Graeme L, Hall K. Distress tolerance across substance use, eating, and borderline personality disorders: a meta-analysis. J Affect Disord. 2022;300:492–504. Review and meta-analysis showing the transdiagnostic role of distress tolerance in substance use, BPD, and disordered eating.

84.

Krueger RF, Tackett JL. Personality and psychopathology: working toward the bigger picture. J Pers Disord. 2003;17(2):109–28.PubMedCrossRef

85.

• Wojciechowski T. Antisocial personality disorder as a predictor of polydrug use: a longitudinal study of the dual mediating roles of deviant peer association and self-control among juvenile offenders. J Ment Health. 2021;1–7. Longitudinal study with 1354 juvenile offenders showing that ASPD diagnosis predicted increased drug use variety, with self-control and deviant peer association as mediators.

86.

• Wojciechowski T. Borderline personality disorder as a predictor of drug use variety: cognitive vs. affective mechanisms. J Psychoactive Drugs. 2022;54(5):452–61. Longitudinal study with 1354 juvenile offenders showing that BPD symptom severity predicted increased drug use variety, with sensation-seeking as a mediator.

87.

Wojciechowski T. Antisocial personality disorder as a risk factor for opioid use: the dual mediating roles of antisocial attitudes and self-control. Journal of Drug Issues. 2021;51(2):268–83.CrossRef

88.

Samek DR, Hicks BM, Iacono WG, McGue M. Personality, romantic relationships, and alcohol use disorder symptoms in adolescence and young adulthood: an evaluation of personality × social context interplay. Dev Psychopathol. 2020;32(3):1097–112.PubMedPubMedCentralCrossRef

89.

Wojciechowski T. Borderline personality disorder symptoms and exposure to violence as risk factors for opioid use in adulthood. Psychiatry Res. 2019;281: 112549.PubMedCrossRef

90.

Walters GD. Does adolescent drug use belong on the antisocial spectrum? Mediating the drug-crime connection with cognitive impulsivity. Int J Law Psychiatry. 2022;80: 101761.PubMedCrossRef

91.

• Lee JY, Pahl K, Kim W. Latent triple trajectories of substance use as predictors for the onset of antisocial personality disorder among urban African American and Puerto Rican adults: a 22-year longitudinal study. Subst Abus. 2022;43(1):442–50. A 22-year longitudinal study using a sample of urban African American and Puerto Rican adults, which showed that early use of alcohol, cigarettes, and cannabis in adolescence was associated with higher risk of adult ASPD onset.

92.

Hasin D, Fenton MC, Skodol A, Krueger R, Keyes K, Geier T, et al. Personality disorders and the 3-year course of alcohol, drug, and nicotine use disorders. Arch Gen Psychiatry. 2011;68(11):1158–67.PubMedPubMedCentralCrossRef

93.

Shah R, Zanarini MC. Comorbidity of borderline personality disorder: current status and future directions. Psychiatr Clin North Am. 2018;41(4):583–93.PubMedCrossRef

94.

Köck P, Walter M. Personality disorder and substance use disorder – an update. Mental Health & Prevention. 2018;1(12):82–9.CrossRef

95.

Edwards ER, Barnes S, Govindarajulu U, Geraci J, Tsai J. Mental health and substance use patterns associated with lifetime suicide attempt, incarceration, and homelessness: a latent class analysis of a nationally representative sample of U.S. veterans. Psychol Serv. 2021;18(4):619–31.

96.

Krasnova A, Eaton WW, Samuels JF. Antisocial personality and risks of cause-specific mortality: results from the Epidemiologic Catchment Area study with 27 years of follow-up. Soc Psychiatry Psychiatr Epidemiol. 2019;54(5):617–25.PubMedCrossRef

97.

Villalobos-Gallegos L, Pérez-Matus S, Valdez-Santiago R, Marín-Navarrete R. Individual contribution of youth antisocial symptoms to suicide behavior in adults with substance use disorders. Arch Suicide Res. 2020;24(sup2):S126–35.PubMedCrossRef

98.

Yen S, Peters JR, Nishar S, Grilo CM, Sanislow CA, Shea MT, et al. Association of borderline personality disorder criteria with suicide attempts: findings from the collaborative longitudinal study of personality disorders over 10 years of follow-up. JAMA Psychiat. 2021;78(2):187–94.CrossRef

99.

Özdemir S, Tunç P. The effects of borderline personality and sociodemographic traits on self-harm and suicidal behavior in substance use disorder. J Psychiatr Nurs. 2022;13(1):15–23.

100.

• Ghinea D, Koenig J, Parzer P, Brunner R, Carli V, Hoven CW, et al. Longitudinal development of risk-taking and self-injurious behavior in association with late adolescent borderline personality disorder symptoms. Psychiatry Res. 2019;273:127–33. Longitudinal study showing associations between the development of alcohol use, self-injurious behaviors, and BPD in adolescents.

Title: The Co-occurrence of Personality Disorders and Substance Use Disorders
Authors: Khrystyna Stetsiv
Ian A. McNamara
Melissa Nance
Ryan W. Carpenter
Publication date: 03-10-2023
Publisher: Springer US
Keyword: Borderline Personality Disorder
Published in: Current Psychiatry Reports / Issue 11/2023
Print ISSN: 1523-3812
Electronic ISSN: 1535-1645
DOI: https://doi.org/10.1007/s11920-023-01452-6

Keynote webinar | Spotlight on medication adherence

Springer Medicine

The Co-occurrence of Personality Disorders and Substance Use Disorders

Abstract

Purpose of Review

Recent Findings

Summary

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Abstract

Purpose of Review

Recent Findings

Summary

Please log in to get access to this content

Other articles of this Issue 11/2023

Digital Tools in the Service of Peer and Social Support for Perinatal Mental Health

A Model of Trust Processes in Borderline Personality Disorder: A Systematic Review

Antipsychotic-Induced Weight Gain in Severe Mental Illness: Risk Factors and Special Considerations

Recent Updates on Predicting Conversion in Youth at Clinical High Risk for Psychosis

Youth Suicidality in the Context of Disasters

Interpersonal Factors, Peer Relationship Stressors, and Gender Differences in Adolescent Depression