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Published in: International Orthopaedics 10/2017

01-10-2017 | Original Paper

Bone substitutes in adolescent idiopathic scoliosis surgery using sublaminar bands: is it useful? A case-control study

Authors: Sebastien Pesenti, Soufiane Ghailane, Jeffrey J. Varghese, Matthieu Ollivier, Emilie Peltier, Elie Choufani, Gerard Bollini, Benjamin Blondel, Jean-Luc Jouve

Published in: International Orthopaedics | Issue 10/2017

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Abstract

Introduction

In order to avoid pseudarthrosis in adolescent idiopathic (AIS) patients, it is recommended to bring additional bone graft or substitute. Modern rigid instrumentations have been shown to provide less pseudarthroses even without bone substitutes. The aim of our study was to determine the impact of using bones substitutes on fusion rates in adolescent idiopathic scoliosis patients undergoing PSF with sublaminar bands.

Method

AIS patients scheduled to undergo PSF with sublaminar bands were prospectively enrolled into this study and not given any bone substitutes (no-substitute group). Data were collected and analyzed in patients with at least two years of follow-up. Pseudarthrosis was diagnosed if at least one of the following was present: persistent back pain, hardware failure, loss of correction greater than 10°. The results were compared to a control group who received bone substitutes for the same surgical procedure.

Results

Eighty-eight patients were included. For the whole cohort, the mean age was 14.8 years old and the mean follow-up was 30.9 months. For the ‘no-substitute’ group (n = 44), the mean Cobb angle was 56° pre-operatively, 20.1° post-operatively, and 22° at final follow-up. The fusion rate was not statistically different between the two groups (97.7% vs 95.5%, p = 0.56). At last follow-up, one pseudarthrosis occurred in the ‘no substitute’ group and two in the control group.

Discussion

This is the first study to determine the impact of bone substitutes in AIS fusion using sublaminar bands. In our study, the use of local autologous bone graft alone resulted in a fusion rate of 97.7% despite the use of more flexible instrumentation. The high rate of fusion in AIS patients is more probably due to the healing potential of these young patients rather than to the type of instrumentation.

Conclusion

The use of additional bone graft or bone substitutes may not be mandatory when managing AIS.
Level of evidence: 4.
Literature
1.
go back to reference Dawson EG, Clader TJ, Bassett LW (1985) A comparison of different methods used to diagnose pseudarthrosis following posterior spinal fusion for scoliosis. J Bone Jt Surg Am 67:1153–1159CrossRef Dawson EG, Clader TJ, Bassett LW (1985) A comparison of different methods used to diagnose pseudarthrosis following posterior spinal fusion for scoliosis. J Bone Jt Surg Am 67:1153–1159CrossRef
2.
go back to reference Bridwell KH, O’Brien MF, Lenke LG, Baldus C, Blanke K (1994) Posterior spinal fusion supplemented with only allograft bone in paralytic scoliosis. Does it work? Spine (Phila Pa 1976) 19:2658–2666CrossRef Bridwell KH, O’Brien MF, Lenke LG, Baldus C, Blanke K (1994) Posterior spinal fusion supplemented with only allograft bone in paralytic scoliosis. Does it work? Spine (Phila Pa 1976) 19:2658–2666CrossRef
3.
4.
go back to reference Theologis AA, Tabaraee E, Lin T et al (2015) Type of bone graft or substitute does not affect outcome of spine fusion with instrumentation for adolescent idiopathic scoliosis. Spine (Phila Pa 1976) 40:1345–1351. doi:10.1097/BRS.0000000000001002 CrossRef Theologis AA, Tabaraee E, Lin T et al (2015) Type of bone graft or substitute does not affect outcome of spine fusion with instrumentation for adolescent idiopathic scoliosis. Spine (Phila Pa 1976) 40:1345–1351. doi:10.​1097/​BRS.​0000000000001002​ CrossRef
5.
go back to reference Betz RR, Petrizzo AM, Kerner PJ, Falatyn SP, Clements DH, Huss GK (2006) Allograft versus no graft with a posterior multisegmented hook system for the treatment of idiopathic scoliosis. Spine (Phila Pa 1976) 31:121–127CrossRef Betz RR, Petrizzo AM, Kerner PJ, Falatyn SP, Clements DH, Huss GK (2006) Allograft versus no graft with a posterior multisegmented hook system for the treatment of idiopathic scoliosis. Spine (Phila Pa 1976) 31:121–127CrossRef
6.
go back to reference Lykissas MG, Jain VV, Nathan ST et al (2013) Mid- to long-term outcomes in adolescent idiopathic scoliosis after instrumented posterior spinal fusion: a meta-analysis. Spine (Phila Pa 1976) 38:E113–E119. doi:10.1097/BRS.0b013e31827ae3d0 CrossRef Lykissas MG, Jain VV, Nathan ST et al (2013) Mid- to long-term outcomes in adolescent idiopathic scoliosis after instrumented posterior spinal fusion: a meta-analysis. Spine (Phila Pa 1976) 38:E113–E119. doi:10.​1097/​BRS.​0b013e31827ae3d0​ CrossRef
7.
go back to reference Mazda K, Ilharreborde B, Even J, Lefevre Y, Fitoussi F, Penneçot GF (2009) Efficacy and safety of posteromedial translation for correction of thoracic curves in adolescent idiopathic scoliosis using a new connection to the spine: the Universal Clamp. Eur Spine J 18:158–169. doi:10.1007/s00586-008-0839-y CrossRefPubMed Mazda K, Ilharreborde B, Even J, Lefevre Y, Fitoussi F, Penneçot GF (2009) Efficacy and safety of posteromedial translation for correction of thoracic curves in adolescent idiopathic scoliosis using a new connection to the spine: the Universal Clamp. Eur Spine J 18:158–169. doi:10.​1007/​s00586-008-0839-y CrossRefPubMed
8.
go back to reference Jouve JL, de Gauzy JS, Blondel B, Launay F, Accadbled F, Bollini G (2010) Use of the Universal Clamp for deformity correction and as an adjunct to fusion: preliminary results in scoliosis. J Child Orthop 4:73–80. doi:10.1007/s11832-009-0221-6 CrossRefPubMed Jouve JL, de Gauzy JS, Blondel B, Launay F, Accadbled F, Bollini G (2010) Use of the Universal Clamp for deformity correction and as an adjunct to fusion: preliminary results in scoliosis. J Child Orthop 4:73–80. doi:10.​1007/​s11832-009-0221-6 CrossRefPubMed
10.
go back to reference Pesenti S, Chalopin A, Peltier E, Choufani E, Ollivier M, Fuentes S, Blondel B, Jouve JL (2016) How sublaminar bands affect postoperative sagittal alignment in AIS patients with preoperative hypokyphosis? Results of a series of 34 patients with 2-year follow-up. Biomed Res Int 1954712. doi: 10.1155/2016/1954712 Pesenti S, Chalopin A, Peltier E, Choufani E, Ollivier M, Fuentes S, Blondel B, Jouve JL (2016) How sublaminar bands affect postoperative sagittal alignment in AIS patients with preoperative hypokyphosis? Results of a series of 34 patients with 2-year follow-up. Biomed Res Int 1954712. doi: 10.​1155/​2016/​1954712
11.
go back to reference Rodriguez-Martinez NG, Safavi-Abbasi S, Perez-Orribo L et al (2015). Biomechanics of a flexible sublaminar connector in long-segment thoracic fixation. J Neurosurg Spine 1–7. doi: 10.3171/2015.4.spine14999 Rodriguez-Martinez NG, Safavi-Abbasi S, Perez-Orribo L et al (2015). Biomechanics of a flexible sublaminar connector in long-segment thoracic fixation. J Neurosurg Spine 1–7. doi: 10.​3171/​2015.​4.​spine14999
12.
go back to reference Fleming JE Jr, Cornell CN, Muschler GF (2000) Bone cells and matrices in orthopedic tissue engineering. Orthop Clin North Am 31:357–374CrossRefPubMed Fleming JE Jr, Cornell CN, Muschler GF (2000) Bone cells and matrices in orthopedic tissue engineering. Orthop Clin North Am 31:357–374CrossRefPubMed
13.
go back to reference Sandhu HS, Grewal HS, Parvataneni H (1999) Bone grafting for spinal fusion. Orthop Clin North Am 30:685–698CrossRefPubMed Sandhu HS, Grewal HS, Parvataneni H (1999) Bone grafting for spinal fusion. Orthop Clin North Am 30:685–698CrossRefPubMed
16.
go back to reference Fabry G (1991) Allograft versus autograft bone in idiopathic scoliosis surgery: a multivariate statistical analysis. J Pediatr Orthop 11:465–468CrossRefPubMed Fabry G (1991) Allograft versus autograft bone in idiopathic scoliosis surgery: a multivariate statistical analysis. J Pediatr Orthop 11:465–468CrossRefPubMed
18.
go back to reference Lansford TJ, Burton DC, Asher MA et al (2013) Radiographic and patient-based outcome analysis of different bone-grafting techniques in the surgical treatment of idiopathic scoliosis with a minimum 4-year follow-up: allograft versus autograft/allograft combination. Spine J 13:523–529. doi:10.1016/j.spinee.2013.01.025 CrossRefPubMed Lansford TJ, Burton DC, Asher MA et al (2013) Radiographic and patient-based outcome analysis of different bone-grafting techniques in the surgical treatment of idiopathic scoliosis with a minimum 4-year follow-up: allograft versus autograft/allograft combination. Spine J 13:523–529. doi:10.​1016/​j.​spinee.​2013.​01.​025 CrossRefPubMed
21.
go back to reference Lerner T, Bullmann V, Schulte TL, Schneider M, Liljenqvist U (2009) A level-1 pilot study to evaluate of ultraporous beta-tricalcium phosphate as a graft extender in the posterior correction of adolescent idiopathic scoliosis. Eur Spine J 18:170–179. doi:10.1007/s00586-008-0844-1 CrossRefPubMed Lerner T, Bullmann V, Schulte TL, Schneider M, Liljenqvist U (2009) A level-1 pilot study to evaluate of ultraporous beta-tricalcium phosphate as a graft extender in the posterior correction of adolescent idiopathic scoliosis. Eur Spine J 18:170–179. doi:10.​1007/​s00586-008-0844-1 CrossRefPubMed
22.
go back to reference Muschik M, Ludwig R, Halbhubner S et al (2001) Beta/tricalcium phosphate as a bone substitute for dorsal spinal fusion in adolescent idiopathic scoliosis: preliminary results of a prospective clinical study. Eur Spine J 10:S178–S184CrossRefPubMedPubMedCentral Muschik M, Ludwig R, Halbhubner S et al (2001) Beta/tricalcium phosphate as a bone substitute for dorsal spinal fusion in adolescent idiopathic scoliosis: preliminary results of a prospective clinical study. Eur Spine J 10:S178–S184CrossRefPubMedPubMedCentral
24.
go back to reference Ransford AO, Morley T, Edgar MA et al (1998) Synthetic porous ceramic compared with autograft in scoliosis surgery. A prospective, randomized study of 341 patients. J Bone Joint Surg Br 80:13–18CrossRefPubMed Ransford AO, Morley T, Edgar MA et al (1998) Synthetic porous ceramic compared with autograft in scoliosis surgery. A prospective, randomized study of 341 patients. J Bone Joint Surg Br 80:13–18CrossRefPubMed
26.
27.
go back to reference Lindaman LM (2001) Bone healing in children. Clin Podiatr Med Surg 18:97–108PubMed Lindaman LM (2001) Bone healing in children. Clin Podiatr Med Surg 18:97–108PubMed
Metadata
Title
Bone substitutes in adolescent idiopathic scoliosis surgery using sublaminar bands: is it useful? A case-control study
Authors
Sebastien Pesenti
Soufiane Ghailane
Jeffrey J. Varghese
Matthieu Ollivier
Emilie Peltier
Elie Choufani
Gerard Bollini
Benjamin Blondel
Jean-Luc Jouve
Publication date
01-10-2017
Publisher
Springer Berlin Heidelberg
Published in
International Orthopaedics / Issue 10/2017
Print ISSN: 0341-2695
Electronic ISSN: 1432-5195
DOI
https://doi.org/10.1007/s00264-017-3512-4

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