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Current Osteoporosis Reports

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01-06-2017 | Kidney and Bone (S Moe and I Salusky, Section Editors)

Bone Quality in Chronic Kidney Disease: Definitions and Diagnostics

Authors: Erin M. B. McNerny, Thomas L. Nickolas

Published in: Current Osteoporosis Reports | Issue 3/2017

Abstract

Purpose of Review

In this paper, we review the epidemiology, diagnosis, and pathogenesis of fractures and renal osteodystrophy.

Recent Findings

The role of bone quality in the pathogenesis of fracture susceptibility in chronic kidney disease (CKD) is beginning to be elucidated. Bone quality refers to bone material properties, such as cortical and trabecular microarchitecture, mineralization, turnover, microdamage, and collagen content and structure. Recent data has added to our understanding of the effects of CKD on alterations to bone quality, emerging data on the role of abnormal collagen structure on bone strength, the potential of non-invasive methods to inform our knowledge of bone quality, and how we can use these methods to inform strategies that protect against bone loss and fractures. However, more prospective data is required.

Summary

CKD is associated with abnormal bone quality and strength which results in high fracture incidence.

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Title: Bone Quality in Chronic Kidney Disease: Definitions and Diagnostics
Authors: Erin M. B. McNerny
Thomas L. Nickolas
Publication date: 01-06-2017
Publisher: Springer US
Published in: Current Osteoporosis Reports / Issue 3/2017
Print ISSN: 1544-1873
Electronic ISSN: 1544-2241
DOI: https://doi.org/10.1007/s11914-017-0366-z

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Bone Quality in Chronic Kidney Disease: Definitions and Diagnostics

Abstract

Purpose of Review

Recent Findings

Summary

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Abstract

Purpose of Review

Recent Findings

Summary

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