Skip to main content
Key Specialties
Cardiology Diabetology Endocrinology Gastroenterology Geriatrics and Gerontology Gynecology and Obstetrics Hematology Infectious Disease Internal Medicine Nephrology Neurology Oncology Pediatrics Respiratory Medicine Rheumatology Surgery
Congress Coverage
2024 ASCO Annual Meeting 2024 ACC Congress 2023 ESMO Congress 2023 EASD Congress 2023 ERS Congress 2023 ESC Congress
Clinical Collections
Advances in Alzheimer’s

2024 ASCO Annual Meeting

Keep up to date with all the top stories and latest evidence with our hub page, including official congress videos and expert takeaways.
ADVANCED SEARCH
Log in
Top
Digestive Diseases and Sciences
Published in: Digestive Diseases and Sciences 1/2015

01-01-2015 | Correspondence

Bone Marrow Cell Therapy and Liver Regeneration: The Potential Clinical Caveat

Authors: Chetana Lim, Dong Broqueres-You, Marc Pocard

Published in: Digestive Diseases and Sciences | Issue 1/2015

Login to get access

Excerpt

We have read with great interest the article by Karibori et al. [1] titled “Bone marrow cells enhance liver regeneration after massive hepatectomy in mice,” published in the July 2014 issue of Digestive Diseases and Sciences. These experimental results are very interesting and validate the concept that bone marrow cell therapy may improve hepatic function and regeneration in the setting of liver resection [2, 3]. However, the following points must be discussed. …
Literature
1.
Karibori M, Adachi Y, Shimo T, et al. Bone marrow cells enhance liver regeneration after massive hepatectomy in mice. Dig Dis Sci. 2014;59:1484–1489.CrossRef
2.
Am Esch JS, Knoefel WT, Klein M, et al. Portal application of autologous CD133+ bone marrow cells to the liver: a novel concept to support hepatic regeneration. Stem Cells 2005;23:463–470.
3.
Am Esch JS, Schmelzle M, Fürst G, et al. Infusion of CD 133+ bone marrow-derived stem cells after selective portal vein embolization enhances functional hepatic reserves after extended right hepatectomy: a retrospective single-center study. Ann Surg. 2012;255:79–85.
4.
Kaplan R.N, Riba R.D, Zacharoulis S, et al. VEGFR1-positive haematopoietic bone marrow progenitors initiate the pre-metastatic niche. Nature 2005;438:820–827.
5.
Gao D, Nolan D, McDonnell K, et al. Bone marrow-derived endothelial progenitor cells contribute to the angiogenic switch in tumor growth and metastatic progression. Biochim Biophys Acta. 2009;1796:33–40.PubMedCentralPubMed
Metadata
Title
Bone Marrow Cell Therapy and Liver Regeneration: The Potential Clinical Caveat
Authors
Chetana Lim
Dong Broqueres-You
Marc Pocard
Publication date
01-01-2015
Publisher
Springer US
Published in
Digestive Diseases and Sciences / Issue 1/2015
Print ISSN: 0163-2116
Electronic ISSN: 1573-2568
DOI
https://doi.org/10.1007/s10620-014-3479-6

Other articles of this Issue 1/2015

Digestive Diseases and Sciences 1/2015 Go to the issue

Original Article

Transenteral Bowel Preparation for Colonoscopy Is More Comfortable than the Traditional Method with No Inferiority in Efficacy

Correspondence

Low SVR Rates in Clinical Practice for Treating Genotype 1 Chronic Hepatitis C with Protease Inhibitors Boceprevir and Telaprevir

Correspondence

Reply “Endoscopic Therapy with 2-Octyl-Cyanoacrylate for the Treatment of Gastric Varices”: Optimizing the Cyanoacrylate Injection in the Treatment of Gastric Varices

UNM Clinical Case Conferences

Unusual Sources of Gastrointestinal Bleeding

Correspondence

Effects of Age at Disease Onset and at Treatment on Serology in Inflammatory Bowel Diseases

Original Article

Viral Suppression and Cirrhosis Regression with Tenofovir Disoproxil Fumarate in Asians with Chronic Hepatitis B
Live Webinar | 27-06-2024 | 18:00 (CEST)

Keynote webinar | Spotlight on medication adherence

Reserve your place

Live: Thursday 27th June 2024, 18:00-19:30 (CEST)

WHO estimates that half of all patients worldwide are non-adherent to their prescribed medication. The consequences of poor adherence can be catastrophic, on both the individual and population level.

Join our expert panel to discover why you need to understand the drivers of non-adherence in your patients, and how you can optimize medication adherence in your clinics to drastically improve patient outcomes.

Prof. Kevin Dolgin
Prof. Florian Limbourg
Prof. Anoop Chauhan
Developed by: Springer Medicine
Obesity Clinical Trial Summary

At a glance: The STEP trials

Read more

A round-up of the STEP phase 3 clinical trials evaluating semaglutide for weight loss in people with overweight or obesity.

Developed by: Springer Medicine
Image Credits