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Drug Safety
Published in: Drug Safety 12/2007

01-12-2007 | Review Article

Bodyweight Changes Associated with Antihyperglycaemic Agents in Type 2 Diabetes Mellitus

Authors: Professor Kjeld Hermansen, Lene S. Mortensen

Published in: Drug Safety | Issue 12/2007

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Abstract

The majority of patients with type 2 diabetes mellitus are overweight or obese at the time of diagnosis, and obesity is a recognised risk factor for type 2 diabetes and coronary heart disease (CHD). Conversely, weight loss has been shown to improve glycaemic control in patients with type 2 diabetes, as well as to lower the risk of CHD. The traditional pharmacotherapies for type 2 diabetes can further increase weight and this may undermine the benefits of improved glycaemic control. Furthermore, patients’ desire to avoid weight gain may jeopardise compliance with treatment, thereby limiting treatment success and indirectly increasing the risk of long-term complications. This review evaluates the influences of established and emerging therapies on bodyweight in type 2 diabetes.
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Metadata
Title
Bodyweight Changes Associated with Antihyperglycaemic Agents in Type 2 Diabetes Mellitus
Authors
Professor Kjeld Hermansen
Lene S. Mortensen
Publication date
01-12-2007
Publisher
Springer International Publishing
Published in
Drug Safety / Issue 12/2007
Print ISSN: 0114-5916
Electronic ISSN: 1179-1942
DOI
https://doi.org/10.2165/00002018-200730120-00005

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