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Published in: World Journal of Surgery 1/2007

01-01-2007

Blood Perfusion of the Free Anterolateral Thigh Perforator Flap: Its Beneficial Effect in the Reconstruction of Infected Wounds in the Lower Extremity

Authors: Andreas Gravvanis, MD, PhD, Dimosthenis Tsoutsos, MD, PhD, Dimitrios Karakitsos, MD, Thomais Iconomou, MD, PhD, Othon Papadopoulos, MD, PhD

Published in: World Journal of Surgery | Issue 1/2007

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Abstract

Background

In a prospective study, we evaluated the blood perfusion and the blood flow of anterolateral thigh (ALT) flap by both near-infrared spectroscopy and color Doppler ultrasonography. Moreover, we assessed the ability of the perforator flap to reconstruct infected wounds of the lower extremity in 11 patients.

Methods

Near-infrared spectroscopy showed excellent oxygen saturation, and Doppler ultrasonography documented excellent blood flow and decreased vascular resistance in the ALT flap postoperatively.

Results

All flaps were successful and all wounds healed uneventfully within 2 weeks without any signs of recurrences or persistent infection. All patients achieved acceptable gait function after rehabilitation.

Conclusions

Apart from the mandatory role of thorough debridement, our results indicate that the ALT flap offers rich blood supply to the recipient area, thus contributing to the sterilization and healing of an infected wound within a short time period.
Literature
1.
go back to reference Godina M. Early microsurgical reconstruction of complex trauma of the extremities. Plast Reconstr Surg 1986;78:285–292PubMed Godina M. Early microsurgical reconstruction of complex trauma of the extremities. Plast Reconstr Surg 1986;78:285–292PubMed
2.
go back to reference Calderon W, Chang N, Mathes SJ. Comparison of the effect of bacterial inoculation in musculocutaneous and random pattern flaps. Plast Reconstr Surg 1986;77:785–794PubMedCrossRef Calderon W, Chang N, Mathes SJ. Comparison of the effect of bacterial inoculation in musculocutaneous and random pattern flaps. Plast Reconstr Surg 1986;77:785–794PubMedCrossRef
3.
go back to reference Mathes SJ, Albert BS, Chang N. Use of the muscle flap in chronic osteomyelitis: experimental and clinical correlation. Plast Reconstr Surg 1982;69:815–829PubMedCrossRef Mathes SJ, Albert BS, Chang N. Use of the muscle flap in chronic osteomyelitis: experimental and clinical correlation. Plast Reconstr Surg 1982;69:815–829PubMedCrossRef
4.
go back to reference Gayle LB, Lineweaver WC, Oliva A, et al. Treatment of chronic osteomyelitis of the lower extremities with debridement and microvascular muscle transfer. Clin Plast Surg 1992;19:895–903PubMed Gayle LB, Lineweaver WC, Oliva A, et al. Treatment of chronic osteomyelitis of the lower extremities with debridement and microvascular muscle transfer. Clin Plast Surg 1992;19:895–903PubMed
5.
go back to reference May JW, Gallico GG, Lukash FN. Microvascular transfer of free tissue for closure of bone wounds of the distal lower extremity. N Engl J Med 1982;306:253–257PubMedCrossRef May JW, Gallico GG, Lukash FN. Microvascular transfer of free tissue for closure of bone wounds of the distal lower extremity. N Engl J Med 1982;306:253–257PubMedCrossRef
6.
go back to reference Gonzalez MH, Weinzweig N. Muscle flaps in the treatment of osteomyelitis of the lower extremity. J Trauma 2005;58:1019–1023PubMed Gonzalez MH, Weinzweig N. Muscle flaps in the treatment of osteomyelitis of the lower extremity. J Trauma 2005;58:1019–1023PubMed
7.
go back to reference Hong JP, Shin HW, Kim JJ, et al. The use of anterolateral thigh perforator flaps in chronic osteomyelitis of the lower extremity. Plast Reconstr Surg 2005;115:142–148PubMedCrossRef Hong JP, Shin HW, Kim JJ, et al. The use of anterolateral thigh perforator flaps in chronic osteomyelitis of the lower extremity. Plast Reconstr Surg 2005;115:142–148PubMedCrossRef
8.
go back to reference Cierney G, Mader JT, Pennick JJ. A clinical staging system of adult osteomyelitis. Contemporary Orthoped 1985;10:17–37 Cierney G, Mader JT, Pennick JJ. A clinical staging system of adult osteomyelitis. Contemporary Orthoped 1985;10:17–37
9.
go back to reference Wei FC, Jain V, Celik N, et al. Have we found an ideal soft-tissue flap? An experience with 672 anterolateral thigh flaps. Plast Reconstr Surg 2002;109:2219–2226PubMedCrossRef Wei FC, Jain V, Celik N, et al. Have we found an ideal soft-tissue flap? An experience with 672 anterolateral thigh flaps. Plast Reconstr Surg 2002;109:2219–2226PubMedCrossRef
10.
go back to reference Gravvanis A, Tsoutsos D, Iconomou T, et al. Penile resurfacing with vascularized fascia lata. Microsurgery 2005;25:462–468PubMedCrossRef Gravvanis A, Tsoutsos D, Iconomou T, et al. Penile resurfacing with vascularized fascia lata. Microsurgery 2005;25:462–468PubMedCrossRef
11.
go back to reference Tsukino A, Kurachi K, Inamiya T, et al. Preoperative color Doppler assessment in planning of anterolateral thigh flaps. Plast Reconstr Surg 2004;113:241–246PubMedCrossRef Tsukino A, Kurachi K, Inamiya T, et al. Preoperative color Doppler assessment in planning of anterolateral thigh flaps. Plast Reconstr Surg 2004;113:241–246PubMedCrossRef
12.
go back to reference Salmi AM, Tierala EK, Tukiainen EJ, et al. Blood flow in free muscle flaps measured by Color Doppler Ultrasonography. Microsurgery 1995;16:666–672PubMed Salmi AM, Tierala EK, Tukiainen EJ, et al. Blood flow in free muscle flaps measured by Color Doppler Ultrasonography. Microsurgery 1995;16:666–672PubMed
13.
go back to reference Taylor DE, Simonson SG. Near infra-red spectroscopy to monitor tissue oxygenation. New Horiz 1996;4:420–425PubMed Taylor DE, Simonson SG. Near infra-red spectroscopy to monitor tissue oxygenation. New Horiz 1996;4:420–425PubMed
14.
go back to reference Chen SL, Chen TM, Lee CH. Free medial sural artery perforator flap for resurfacing distal limb defects. J Trauma 2005;58:323–327PubMedCrossRef Chen SL, Chen TM, Lee CH. Free medial sural artery perforator flap for resurfacing distal limb defects. J Trauma 2005;58:323–327PubMedCrossRef
15.
go back to reference Musharafieh R, Atiyeh B, Macari G, et al. Radial forearm fasciocutaneous free tissue transfer in ankle and foot reconstruction: review of 17 cases. J Reconstruct Microsurg 2001;17:147–150CrossRef Musharafieh R, Atiyeh B, Macari G, et al. Radial forearm fasciocutaneous free tissue transfer in ankle and foot reconstruction: review of 17 cases. J Reconstruct Microsurg 2001;17:147–150CrossRef
16.
go back to reference Chen D, Jupiter JB, Lipton HA, et al. The parascapular flap for treatment of lower extremity disorders. Plast Reconstr Surg 1989;84:108–116PubMedCrossRef Chen D, Jupiter JB, Lipton HA, et al. The parascapular flap for treatment of lower extremity disorders. Plast Reconstr Surg 1989;84:108–116PubMedCrossRef
17.
go back to reference Koshima I, Nanba Y, Tsutsui T, et al. Perforator flaps in lower extremity reconstruction. Handchir Mikrochir Plast Chir 2002;34:251–256PubMedCrossRef Koshima I, Nanba Y, Tsutsui T, et al. Perforator flaps in lower extremity reconstruction. Handchir Mikrochir Plast Chir 2002;34:251–256PubMedCrossRef
18.
go back to reference Gravvanis A, Iconomou T, Panayotou P, et al. Medial gastrocnemius muscle flap vs distally based anterolateal thigh flap: conservative or modern approach to the exposed knee joint? Plast Reconstr Surg 2005;116:932–935PubMedCrossRef Gravvanis A, Iconomou T, Panayotou P, et al. Medial gastrocnemius muscle flap vs distally based anterolateal thigh flap: conservative or modern approach to the exposed knee joint? Plast Reconstr Surg 2005;116:932–935PubMedCrossRef
19.
go back to reference Attinger CE, Bulan EJ. Debridement. The key initial first step in wound healing. Foot Ankle Clin 2001;6:627–660PubMedCrossRef Attinger CE, Bulan EJ. Debridement. The key initial first step in wound healing. Foot Ankle Clin 2001;6:627–660PubMedCrossRef
20.
go back to reference Chen HC, Tang YB. Anterolateral thigh flap: an ideal soft tissue flap. Clin Plast Surg 2003;30:383–401PubMedCrossRef Chen HC, Tang YB. Anterolateral thigh flap: an ideal soft tissue flap. Clin Plast Surg 2003;30:383–401PubMedCrossRef
21.
go back to reference Rubino C, Coscia V, Cavazzuti AM, et al. Haemodynamic enhancement in perforator flaps: the inversion phenomenon and its clinical significance. A study of the relation of blood velocity and flow between pedicle and perforator vessels in perforator flaps. Br J Plast Surg 2005 Nov 22; [Epub ahead of print] Rubino C, Coscia V, Cavazzuti AM, et al. Haemodynamic enhancement in perforator flaps: the inversion phenomenon and its clinical significance. A study of the relation of blood velocity and flow between pedicle and perforator vessels in perforator flaps. Br J Plast Surg 2005 Nov 22; [Epub ahead of print]
22.
go back to reference Lorenzetti F, Salmi A, Ahovuo J, et al. Postoperative changes in blood flow in free muscle flaps: a prospective study. Microsurgery 1999;19:196–199PubMedCrossRef Lorenzetti F, Salmi A, Ahovuo J, et al. Postoperative changes in blood flow in free muscle flaps: a prospective study. Microsurgery 1999;19:196–199PubMedCrossRef
23.
go back to reference Lorenzetti F, Suominen S, Tukiainen E, et al. Evaluation of blood flow in free microvascular flaps. J Reconstr Microsurg 2001;17:163–167PubMedCrossRef Lorenzetti F, Suominen S, Tukiainen E, et al. Evaluation of blood flow in free microvascular flaps. J Reconstr Microsurg 2001;17:163–167PubMedCrossRef
24.
go back to reference Lorenzetti F, Ahovuo J, Suominen S, et al. Colour Doppler ultrasound evaluation of haemodynamic changes in free tram flaps and their donor sites. Scand J Plast Reconstr Surg Hand Surg 2002;36:202–206PubMedCrossRef Lorenzetti F, Ahovuo J, Suominen S, et al. Colour Doppler ultrasound evaluation of haemodynamic changes in free tram flaps and their donor sites. Scand J Plast Reconstr Surg Hand Surg 2002;36:202–206PubMedCrossRef
25.
go back to reference Taylor KJW, Holland S. Doppler US. Part I. Basic principles, instrumentation and pitfalls. Radiology 1990;174:297–307PubMed Taylor KJW, Holland S. Doppler US. Part I. Basic principles, instrumentation and pitfalls. Radiology 1990;174:297–307PubMed
26.
go back to reference Thorniley MS, Lahiri A, Glenville B, et al. Non invasive measurements of cardiac oxygenation and haemodynamics during transient episodes of coronary artery occlusion and reperfusion. Clin Sci 1996;91:51–58PubMed Thorniley MS, Lahiri A, Glenville B, et al. Non invasive measurements of cardiac oxygenation and haemodynamics during transient episodes of coronary artery occlusion and reperfusion. Clin Sci 1996;91:51–58PubMed
27.
go back to reference du Plessis AJ, Newburger J, Jonas RA, et al. Cerebral oxygen supply and utilization during infant cardiac surgery. Ann Neurol 1995;37:488–497PubMedCrossRef du Plessis AJ, Newburger J, Jonas RA, et al. Cerebral oxygen supply and utilization during infant cardiac surgery. Ann Neurol 1995;37:488–497PubMedCrossRef
28.
go back to reference Lane N, Thorniley MS, Manek S, et al. Secondary ischaemia and tissue damage in transplanted stored kidneys. Transplantation 1996;61:689–696PubMedCrossRef Lane N, Thorniley MS, Manek S, et al. Secondary ischaemia and tissue damage in transplanted stored kidneys. Transplantation 1996;61:689–696PubMedCrossRef
29.
go back to reference Scheufler O, Exner K, Andresen R. Investigation of TRAM flap oxygenation and perfusion by near-infrared refraction spectroscopy and color-coded duplex sonography. Plast Reconstr Surg 2004;113:141–151PubMedCrossRef Scheufler O, Exner K, Andresen R. Investigation of TRAM flap oxygenation and perfusion by near-infrared refraction spectroscopy and color-coded duplex sonography. Plast Reconstr Surg 2004;113:141–151PubMedCrossRef
30.
go back to reference Holzle F, Loeffelbein DJ, Nolte D, et al. Free flap monitoring using simultaneous non-invasive laser Doppler flowmetry and tissue spectrophotometry. J Craniomaxillofac Surg 2006;34:25–33PubMed Holzle F, Loeffelbein DJ, Nolte D, et al. Free flap monitoring using simultaneous non-invasive laser Doppler flowmetry and tissue spectrophotometry. J Craniomaxillofac Surg 2006;34:25–33PubMed
Metadata
Title
Blood Perfusion of the Free Anterolateral Thigh Perforator Flap: Its Beneficial Effect in the Reconstruction of Infected Wounds in the Lower Extremity
Authors
Andreas Gravvanis, MD, PhD
Dimosthenis Tsoutsos, MD, PhD
Dimitrios Karakitsos, MD
Thomais Iconomou, MD, PhD
Othon Papadopoulos, MD, PhD
Publication date
01-01-2007
Publisher
Springer-Verlag
Published in
World Journal of Surgery / Issue 1/2007
Print ISSN: 0364-2313
Electronic ISSN: 1432-2323
DOI
https://doi.org/10.1007/s00268-006-0298-8

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