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Skeletal Radiology
Published in: Skeletal Radiology 6/2007

01-06-2007 | Case Report

Bizarre parosteal osteochondromatous proliferation of the proximal humerus: case report

Authors: J. Bernard Bush, John D. Reith, Mark S. Meyer

Published in: Skeletal Radiology | Issue 6/2007

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Abstract

Bizarre parosteal osteochondromatous proliferation (BPOP), or Nora’s lesion, is a rare lesion of bone occurring predominantly in the long bones of the hands and feet. It exists as a puzzling clinical entity of uncertain origins and high recurrence rates after surgical resection. To our knowledge, this clinical entity has not been reported in the proximal aspect of the humerus. An interesting report of a lesion occurring in the proximal humerus, which initially was misinterpreted as a parosteal osteosarcoma, is discussed outlining the clinical, radiographic and pathologic features of the BPOP lesion.
Literature
1.
Nora FE, Dahlin DC, Beabout JW. Bizarre parosteal osteochondromatous proliferations of the hands and feet. Am J Surg Pathol 1983;7:245–50.CrossRef
2.
Meneses MF, Unni KK, Swee RG. Bizarre parosteal osteochondromatous proliferation of bone (Nora’s Lesion). Am J Surg Pathol 1993;17:691–7.CrossRef
3.
Twiston Davies CW. Bizarre parosteal osteochondromatous proliferation in the hand. A case report. J Bone Jt Surg Am 1985;67:648–50.CrossRef
4.
de Lange FE, Pope TL, Fechner RE, Keats TE. Case report 428: Bizarre parosteal osteochondromatous proliferation (BPOP). Skelet Radiol 1987;16:481–3.CrossRef
5.
Lindeque BG, Simson IW, Fourie PA. Bizarre parosteal osteochondromatous proliferation of a phalanx. Arch Orthop Trauma Surg 1990;110:58–60.CrossRef
6.
Teoh HH, Bethwaite PB, Thurston AJ. Bizarre parosteal osteochondromatous proliferation of the hand in a young man. Pathology 1992;24:211–3.CrossRef
7.
Yuen M, Friedman L, Orr W, Cockshott WP. Proliferative periosteal processes of phalanges: a unitary hypothesis. Skelet Radiol 1992;21:301–3.CrossRef
8.
Nilsson M, Domanski HA, Mertens F, Mandahl N. Molecular cytogenetic characterization of recurrent translocation breakpoints in bizarre parosteal osteochondromatous proliferation (Nora’s lesion). Hum Pathol 2004;35:1063–9.CrossRef
9.
Rungsipipat A, Yamaguchi R, Naganobu K, et al. A bone tumour resembling bizarre parosteal osteochondromatous proliferation in a wallaby. Aust Vet J 1998;76:561–4.CrossRef
10.
Ouri H, Ishikawa A, Tsuchiya T, Ogino T. Magnetic resonance imaging characteristics of bizarre parosteal osteochondromatous proliferation of the hand. A case report. J Hand Surg 2002;27:1104–8.CrossRef
11.
Ly JQ, Bui-Mansfield LT, Taylor DC. Radiologic demonstration of temporal development of bizarre parosteal osteochondromatous proliferation. J Clin Imaging 2004;28:216–8.CrossRef
12.
Michelsen H, Abramovici L, Steiner G, Posner MA. Bizarre parosteal osteochondromatous proliferation (Nora’s Lesion) in the hand. J Hand Surg 2004;29:520–5.CrossRef
13.
Godbee MT, Griffiths HJ. Radiologic case study. Bizarre parosteal osteochondromatous proliferation (Nora’s lesion) of bone. Orthopedics 2002;25:699–700.
14.
van der Walt JD, Ryan JF. Parosteal osteogenic sarcoma of the hand. Histopathology 1990;16:75–80.CrossRef
15.
Tannenbaum DA, Biermann JS. Bizarre parosteal osteochondromatous proliferation of bone. Orthopedics 1997;20:1186–8.PubMed
16.
Soon JL, Chang HC, Sim CS, Teoh LC, Low CO. A case of bizarre parosteal osteochondromatous proliferation of the hand. Singapore Med J 2003;44:27–30.PubMed
17.
Helliwell TR, O’Connor MA, Ritchie DA, Feldberg L, Stilwell JH, Jane MJ. Bizarre parosteal osteochondromatous proliferation with cortical invasion. Skelet Radiol 2001;30:282–5.CrossRef
18.
Choi JH, Gu MJ, Kim MJ, Choi DS, Cho KH. Fibrosarcoma in bizarre parosteal osteochondromatous proliferation. Skelet Radiol 2001;30:44–7.CrossRef
19.
Zambrano E, Nose V, Perez-Atayde AR, et al. Distinct chromosomal rearrangements in subungual (Dupuytren) exostosis and bizarre parosteal osteochondromatous proliferation (Nora’s Lesion). Am J Surg Pathol 2004;28:1033–9.CrossRef
20.
Gerber C, Schneeberger AG, Vinh TS. The arterial vascularization of the humeral head. An anatomic study. J Bone Jt Surg Am 1990;72:1486–94.CrossRef
21.
Laing PG. The arterial supply of the adult humerus. J Bone Jt Surg 1956;38:1105–16.CrossRef
22.
Lee CK, Hansen HR. Post-traumatic avascular necrosis of the humeral head in displaced proximal humeral fractures. J Trauma 1981;21:788–91.CrossRef
23.
Leyson RL. Closed treatment of fractures of the proximal humerus. Acta Orthop Scand 1984;55:48–51.CrossRef
24.
Wijgman AJ, Roolker W, Patt TW, Raaymakers EL, Marti RK. Open reduction and internal fixation of three and four-part fractures of the proximal part of the humerus. J Bone Jt Surg Am 2002;84:1919–25.CrossRef
Metadata
Title
Bizarre parosteal osteochondromatous proliferation of the proximal humerus: case report
Authors
J. Bernard Bush
John D. Reith
Mark S. Meyer
Publication date
01-06-2007
Publisher
Springer Berlin Heidelberg
Published in
Skeletal Radiology / Issue 6/2007
Print ISSN: 0364-2348
Electronic ISSN: 1432-2161
DOI
https://doi.org/10.1007/s00256-006-0236-8

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