Skip to main content
Top
Published in: BMC Psychiatry 1/2021

Open Access 01-12-2021 | Research article

Bipolar I disorder: a qualitative study of the viewpoints of the family members of patients on the nature of the disorder and pharmacological treatment non-adherence

Authors: Nasim Mousavi, Marzieh Norozpour, Zahra Taherifar, Morteza Naserbakht, Amir Shabani

Published in: BMC Psychiatry | Issue 1/2021

Login to get access

Abstract

Background

Bipolar disorder is a common psychiatric disorder with a massive psychological and social burden. Research indicates that treatment adherence is not good in these patients. The families’ knowledge about the disorder is fundamental for managing their patients’ disorder. The purpose of the present study was to investigate the knowledge of the family members of a sample of Iranian patients with bipolar I disorder (BD-I) and to explore the potential reasons for treatment non-adherence.

Methods

This study was conducted by qualitative content analysis. In-depth interviews were held and open-coding inductive analysis was performed. A thematic content analysis was used for the qualitative data analysis.

Results

The viewpoints of the family members of the patients were categorized in five themes, including knowledge about the disorder, information about the medications, information about the treatment and the respective role of the family, reasons for pharmacological treatment non-adherence, and strategies applied by families to enhance treatment adherence in the patients. The research findings showed that the family members did not have enough information about the nature of BD-I, which they attributed to their lack of training on the disorder. The families did not know what caused the recurrence of the disorder and did not have sufficient knowledge about its prescribed medications and treatments. Also, most families did not know about the etiology of the disorder.

Conclusion

The lack of knowledge among the family members of patients with BD-I can have a significant impact on relapse and treatment non-adherence. These issues need to be further emphasized in the training of patients’ families. The present findings can be used to re-design the guidelines and protocols in a way to improve treatment adherence and avoid the relapse of BD-I symptoms.
Footnotes
1
A popular comedy show on Iranian television
 
Literature
1.
go back to reference Diagnostic and statistical manual of mental disorders. Fifth edition (DSM-5). Arlington: American Psychiatric Association; 2013. Diagnostic and statistical manual of mental disorders. Fifth edition (DSM-5). Arlington: American Psychiatric Association; 2013.
2.
go back to reference Kaushik P, Bhatia M. Burden and quality of life in spouses of patients with schizophrenia and bipolar disorder. Delhi Psychiatry J. 2013;16(1):83-9. Kaushik P, Bhatia M. Burden and quality of life in spouses of patients with schizophrenia and bipolar disorder. Delhi Psychiatry J. 2013;16(1):83-9.
4.
go back to reference Zergew A, Hailemariam D, Alem A, Kebede D. A longitudinal comparative analysis of economic and family caregiver burden due to bipolar disorder. Afr J Psychiatry. 2008;11(3):191–8.CrossRef Zergew A, Hailemariam D, Alem A, Kebede D. A longitudinal comparative analysis of economic and family caregiver burden due to bipolar disorder. Afr J Psychiatry. 2008;11(3):191–8.CrossRef
5.
go back to reference Shirkhoda SA. The investigation of the amount of cost for bipolar disorder type I and its related factors during the 1-year follow-up for the hospitalized patients in Iran educational-therapeutic psychiatric center [dissertaion]. Iran University of Medical Sciences ;2014. Shirkhoda SA. The investigation of the amount of cost for bipolar disorder type I and its related factors during the 1-year follow-up for the hospitalized patients in Iran educational-therapeutic psychiatric center [dissertaion]. Iran University of Medical Sciences ;2014.
6.
go back to reference Jönsson PD, Skärsäter I, Wijk H, Danielson E. Experience of living with a family member with bipolar disorder. Int J Ment Health Nurs. 2011;20(1):29–37.CrossRef Jönsson PD, Skärsäter I, Wijk H, Danielson E. Experience of living with a family member with bipolar disorder. Int J Ment Health Nurs. 2011;20(1):29–37.CrossRef
7.
go back to reference Shabani A, Ahmadzad-Asl M, Zangeneh K, Teimurinejad S, Kokar S, Taban M, et al. Quality of life in patients with bipolar I disorder: is it related to disorder outcome? Acta Med Iran 2013:51(6):386-93. Shabani A, Ahmadzad-Asl M, Zangeneh K, Teimurinejad S, Kokar S, Taban M, et al. Quality of life in patients with bipolar I disorder: is it related to disorder outcome? Acta Med Iran 2013:51(6):386-93.
8.
go back to reference Clatworthy J, Bowskill R, Rank T, Parham R, Horne R. Adherence to medication in bipolar disorder: a qualitative study exploring the role of patients’ beliefs about the condition and its treatment. Bipolar Disord 2007;9(6):656-64. Clatworthy J, Bowskill R, Rank T, Parham R, Horne R. Adherence to medication in bipolar disorder: a qualitative study exploring the role of patients’ beliefs about the condition and its treatment. Bipolar Disord 2007;9(6):656-64.
9.
go back to reference Sharifi A, Shabani A, Ahmadzadasl M. The pattern of adherence in patients with bipolar I disorder; an eight weeks study: Iranian Journal of Psychiatry and Behav Sci 2009;3(2):39-43. Sharifi A, Shabani A, Ahmadzadasl M. The pattern of adherence in patients with bipolar I disorder; an eight weeks study: Iranian Journal of Psychiatry and Behav Sci 2009;3(2):39-43.
10.
go back to reference Shabani A, Eftekhar M. Non Compliance After First Episode of Manic or Mixed Mood State: A 17-Month Follow-up. 2007;1(2):46-49. Shabani A, Eftekhar M. Non Compliance After First Episode of Manic or Mixed Mood State: A 17-Month Follow-up. 2007;1(2):46-49.
11.
go back to reference Tacchi M-J, Scott J. Improving adherence in schizophrenia and bipolar disorders: Wiley; 2005;7:24-31. Tacchi M-J, Scott J. Improving adherence in schizophrenia and bipolar disorders: Wiley; 2005;7:24-31.
12.
go back to reference Velligan D, Weiden P, Sajatovic M, Scott J, Carpenter D, Ross R, et al. Expert Consensus Panel on Adherence Problems in Serious and Persistent Mental Illness. The expert consensus guideline series: adherence problems in patients with serious and persistent mental illness. J Clin Psychiatry 2009;70(suppl 4):1-46. Velligan D, Weiden P, Sajatovic M, Scott J, Carpenter D, Ross R, et al. Expert Consensus Panel on Adherence Problems in Serious and Persistent Mental Illness. The expert consensus guideline series: adherence problems in patients with serious and persistent mental illness. J Clin Psychiatry 2009;70(suppl 4):1-46.
13.
go back to reference Shabani A, Sobhani S, Tahmasebi N, Ghahramani S, Dejman M: How family caregivers of patients with bipolar disorder conceptualize caring problems: a qualitative study, unpublished. Shabani A, Sobhani S, Tahmasebi N, Ghahramani S, Dejman M: How family caregivers of patients with bipolar disorder conceptualize caring problems: a qualitative study, unpublished.
14.
go back to reference Tong A, Sainsbury P, Craig J. Consolidated criteria for reporting qualitative research (COREQ): a 32-item checklist for interviews and focus groups. Int J Qual Health Care 2007;19(6):349-57. Tong A, Sainsbury P, Craig J. Consolidated criteria for reporting qualitative research (COREQ): a 32-item checklist for interviews and focus groups. Int J Qual Health Care 2007;19(6):349-57.
15.
go back to reference Fusch PI, Ness LR. Are we there yet? Data saturation in qualitative research. Qual Rep. 2015;20(9):1408. Fusch PI, Ness LR. Are we there yet? Data saturation in qualitative research. Qual Rep. 2015;20(9):1408.
16.
go back to reference Clarke V, Braun V. Using thematic analysis in counselling and psychotherapy research: A critical reflection. Couns Psychother Res 2018;18(2):107-10. Clarke V, Braun V. Using thematic analysis in counselling and psychotherapy research: A critical reflection. Couns Psychother Res 2018;18(2):107-10.
17.
go back to reference Braun V, Clarke V. Using thematic analysis in psychology. Qual Res Psychol 2006;3(2):77-101. Braun V, Clarke V. Using thematic analysis in psychology. Qual Res Psychol 2006;3(2):77-101.
18.
go back to reference Chakrabarti S. Treatment-adherence in bipolar disorder: a patient-centred approach. World J Psychiatry 2016;6(4):399. Chakrabarti S. Treatment-adherence in bipolar disorder: a patient-centred approach. World J Psychiatry 2016;6(4):399.
19.
go back to reference Shamsaei F, Mohammadkhan Kermanshahi S, Vanaki Z. Survey of Family Caregiver Needs of Patients with Bipolar Disorder. Avicenna J Clin Med 2010;17(3):57-63. Shamsaei F, Mohammadkhan Kermanshahi S, Vanaki Z. Survey of Family Caregiver Needs of Patients with Bipolar Disorder. Avicenna J Clin Med 2010;17(3):57-63.
20.
go back to reference Rahmani F, Ebrahimi H, Ranjbar F, Asghari E. The effect of group psychoeducational program on attitude toward mental illness in family caregivers of patients with bipolar disorder. Hayat. 2016;21(4):65-79. Rahmani F, Ebrahimi H, Ranjbar F, Asghari E. The effect of group psychoeducational program on attitude toward mental illness in family caregivers of patients with bipolar disorder. Hayat. 2016;21(4):65-79.
21.
go back to reference MacDonald L, Chapman S, Syrett M, Bowskill R, Horne R. Improving medication adherence in bipolar disorder: A systematic review and meta-analysis of 30 years of intervention trials. J Affect Disord 2016;194:202-21. MacDonald L, Chapman S, Syrett M, Bowskill R, Horne R. Improving medication adherence in bipolar disorder: A systematic review and meta-analysis of 30 years of intervention trials. J Affect Disord 2016;194:202-21.
22.
go back to reference Wright JH. Cognitive-behavior therapy for severe mental illness: An illustrated guide: American Psychiatric Pub; 2009. Wright JH. Cognitive-behavior therapy for severe mental illness: An illustrated guide: American Psychiatric Pub; 2009.
23.
go back to reference Peters S, Pontin E, Lobban F, Morriss R. Involving relatives in relapse prevention for bipolar disorder: a multi-perspective qualitative study of value and barriers. BMC Psychiatry 2011;11(1):172. Peters S, Pontin E, Lobban F, Morriss R. Involving relatives in relapse prevention for bipolar disorder: a multi-perspective qualitative study of value and barriers. BMC Psychiatry 2011;11(1):172.
24.
go back to reference Farhoudian A, Rad Goodarzi R, Rahimi Movaghar A, Sharifi V, Mohammadi MR, Sahimi Izadian E, et al. Trend of Researches in the Field of Psychiatric Disorders in Iran. Iran J Psychiatry Clin Psychol 2007;12(4):327-36. Farhoudian A, Rad Goodarzi R, Rahimi Movaghar A, Sharifi V, Mohammadi MR, Sahimi Izadian E, et al. Trend of Researches in the Field of Psychiatric Disorders in Iran. Iran J Psychiatry Clin Psychol 2007;12(4):327-36.
25.
go back to reference Fisher A, Manicavasagar V, Sharpe L, Laidsaar-Powell R, Juraskova I. A qualitative exploration of patient and family views and experiences of treatment decision-making in bipolar II disorder. J Ment Health 2018;27(1):66-79. Fisher A, Manicavasagar V, Sharpe L, Laidsaar-Powell R, Juraskova I. A qualitative exploration of patient and family views and experiences of treatment decision-making in bipolar II disorder. J Ment Health 2018;27(1):66-79.
26.
go back to reference Jönsson PD, Wijk H, Skärsäter I, Danielson E. Persons living with bipolar disorder—their view of the illness and the future. Issues Mental Health Nurs 2008;29(11):1217-36.27. Jönsson PD, Wijk H, Skärsäter I, Danielson E. Persons living with bipolar disorder—their view of the illness and the future. Issues Mental Health Nurs 2008;29(11):1217-36.27.
27.
go back to reference Shamsaei F, Mohamad khan Kermanshahi S, Vanaki Z. Meaning of Health from the Perspective of Family Member Caregiving to Patients with Bipolar Disorder. Journal of Mazandaran University of Medical Sciences. 2012;22(90):52-65. Shamsaei F, Mohamad khan Kermanshahi S, Vanaki Z. Meaning of Health from the Perspective of Family Member Caregiving to Patients with Bipolar Disorder. Journal of Mazandaran University of Medical Sciences. 2012;22(90):52-65.
28.
go back to reference Scott J, Pope M. Nonadherence with mood stabilizers: prevalence and predictors. J Clin Psychiatry 2002;63(5):384-390. Scott J, Pope M. Nonadherence with mood stabilizers: prevalence and predictors. J Clin Psychiatry 2002;63(5):384-390.
29.
go back to reference Delmas K, Proudfoot J, Parker G, Manicavasagar V. Recoding past experiences: A qualitative study of how patients and family members adjust to the diagnosis of bipolar disorder. J Nerv Ment Dis 2011;199(2):136-9. Delmas K, Proudfoot J, Parker G, Manicavasagar V. Recoding past experiences: A qualitative study of how patients and family members adjust to the diagnosis of bipolar disorder. J Nerv Ment Dis 2011;199(2):136-9.
30.
go back to reference Proudfoot JG, Parker GB, Benoit M, Manicavasagar V, Smith M, Gayed A. What happens after diagnosis? Understanding the experiences of patients with newly-diagnosed bipolar disorder. Health Expect 2009;12(2):120-9. Proudfoot JG, Parker GB, Benoit M, Manicavasagar V, Smith M, Gayed A. What happens after diagnosis? Understanding the experiences of patients with newly-diagnosed bipolar disorder. Health Expect 2009;12(2):120-9.
31.
go back to reference Crowe M, Inder M, Carlyle D, Wilson L, Whitehead L, Panckhurst A, et al. Feeling out of control: a qualitative analysis of the impact of bipolar disorder. J Psychiatr Ment Health Nurs 2012;19(4):294-302. Crowe M, Inder M, Carlyle D, Wilson L, Whitehead L, Panckhurst A, et al. Feeling out of control: a qualitative analysis of the impact of bipolar disorder. J Psychiatr Ment Health Nurs 2012;19(4):294-302.
32.
go back to reference Weiss RD, Greenfield SF, Najavits LM, Soto JA, Wyner D, Tohen M, et al. Medication compliance among patients with bipolar disorder and substance use disorder. J Clin Psychiatry 1998;59(4):172-4. Weiss RD, Greenfield SF, Najavits LM, Soto JA, Wyner D, Tohen M, et al. Medication compliance among patients with bipolar disorder and substance use disorder. J Clin Psychiatry 1998;59(4):172-4.
33.
go back to reference Judd LL, Akiskal HS, Schettler PJ, Endicott J, Maser J, Solomon DA, et al. The long-term natural history of the weekly symptomatic status of bipolar I disorder. Arch Gen Psychiatry 2002;59(6):530-7. Judd LL, Akiskal HS, Schettler PJ, Endicott J, Maser J, Solomon DA, et al. The long-term natural history of the weekly symptomatic status of bipolar I disorder. Arch Gen Psychiatry 2002;59(6):530-7.
34.
go back to reference Judd LL, Schettler PJ, Akiskal HS, Maser J, Coryell W, Solomon D, et al. Long-term symptomatic status of bipolar I vs. bipolar II disorders. Int J Neuropsychopharmacol 2003;6(2):127-37. Judd LL, Schettler PJ, Akiskal HS, Maser J, Coryell W, Solomon D, et al. Long-term symptomatic status of bipolar I vs. bipolar II disorders. Int J Neuropsychopharmacol 2003;6(2):127-37.
Metadata
Title
Bipolar I disorder: a qualitative study of the viewpoints of the family members of patients on the nature of the disorder and pharmacological treatment non-adherence
Authors
Nasim Mousavi
Marzieh Norozpour
Zahra Taherifar
Morteza Naserbakht
Amir Shabani
Publication date
01-12-2021
Publisher
BioMed Central
Published in
BMC Psychiatry / Issue 1/2021
Electronic ISSN: 1471-244X
DOI
https://doi.org/10.1186/s12888-020-03008-x

Other articles of this Issue 1/2021

BMC Psychiatry 1/2021 Go to the issue