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Published in: Archives of Orthopaedic and Trauma Surgery 9/2011

01-09-2011 | Orthopaedic Surgery

Biomechanical comparison of different techniques in primary spinal surgery in osteoporotic cadaveric lumbar vertebrae: expansive pedicle screw versus polymethylmethacrylate-augmented pedicle screw

Authors: Da Liu, Zi-xiang Wu, Xian-ming Pan, Suo-chao Fu, Ming-xuan Gao, Lei Shi, Wei Lei

Published in: Archives of Orthopaedic and Trauma Surgery | Issue 9/2011

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Abstract

Introduction

Transpedicular fixation can be challenging in the osteoporotic spine. Expansive pedicle screw (EPS) and polymethylmethacrylate-augmented pedicle screw (PMMA-PS) were both used to increase screw stability. However, there are a little or no biomechanical comparisons of EPS and PMMA-PS, especially in primary spinal surgery in osteoporotic vertebrae. The purpose of this study was to compare the stability of EPS and PMMA-PS in primary spinal surgery.

Materials and methods

Fifteen osteoporotic vertebrae were randomly divided into three groups. The conventional pedicle screw (CPS) was inserted in CPS group, the pilot hole was filled with PMMA followed by CPS insertion in PMMA-PS group, and EPS was inserted in EPS group. Twenty-four hours later, X-ray and CT examination and biomechanical tests were performed to all vertebrae.

Results

In PMMA-PS group, PMMA existed in bone tissue around the CPS in both vertebral body and pedicle of vertebral arch, and PMMA surrounding the screw formed a spindle-shaped structure in vertebral body. In EPS group, anterior part of EPS presented an obvious expansion in vertebral body and formed a clawlike structure. Screw stabilities in PMMA-PS and EPS groups were significantly enhanced compared with those in CPS group (P < 0.05). However, there was no significant difference between PMMA-PS and EPS groups (P > 0.05).

Conclusion

Expansive pedicle screw can markedly enhance screw stability with a similar effect to the traditional method of screw augmentation with PMMA in primary surgery in osteoporotic vertebrae. In addition, EPS can overcome pedicle fracture, leakage and compression caused by lager screw and augmentation with PMMA. We propose that EPS is an effective, safe and easy method and has a great application potential in augmentation of screw stability in osteoporosis in clinic.
Literature
1.
go back to reference Boucher HH (1959) A method of spinal fusion. J Bone Joint Surg Br 41-B:248–259PubMed Boucher HH (1959) A method of spinal fusion. J Bone Joint Surg Br 41-B:248–259PubMed
2.
go back to reference Tokuhashi Y, Ajiro Y, Umezawa N (2008) Outcomes of posterior fusion using pedicle screw fixation in patients > or = 70 years with lumbar spinal canal stenosis. Orthopedics 31:1096PubMed Tokuhashi Y, Ajiro Y, Umezawa N (2008) Outcomes of posterior fusion using pedicle screw fixation in patients > or = 70 years with lumbar spinal canal stenosis. Orthopedics 31:1096PubMed
3.
go back to reference Fisher C, Singh S, Boyd M et al (2009) Clinical and radiographic outcomes of pedicle screw fixation for upper thoracic spine (T1–5) fractures: a retrospective cohort study of 27 cases. J Neurosurg Spine 10:207–213PubMedCrossRef Fisher C, Singh S, Boyd M et al (2009) Clinical and radiographic outcomes of pedicle screw fixation for upper thoracic spine (T1–5) fractures: a retrospective cohort study of 27 cases. J Neurosurg Spine 10:207–213PubMedCrossRef
4.
go back to reference Hee HT, Yu ZR, Wong HK (2007) Comparison of segmental pedicle screw instrumentation versus anterior instrumentation in adolescent idiopathic thoracolumbar and lumbar scoliosis. Spine (Phila Pa 1976) 32:1533–1542CrossRef Hee HT, Yu ZR, Wong HK (2007) Comparison of segmental pedicle screw instrumentation versus anterior instrumentation in adolescent idiopathic thoracolumbar and lumbar scoliosis. Spine (Phila Pa 1976) 32:1533–1542CrossRef
5.
go back to reference Frankel BM, Jones T, Wang C (2007) Segmental polymethylmethacrylate-augmented pedicle screw fixation in patients with bone softening caused by osteoporosis and metastatic tumor involvement: a clinical evaluation. Neurosurgery 61:531–537 discussion 537–538PubMedCrossRef Frankel BM, Jones T, Wang C (2007) Segmental polymethylmethacrylate-augmented pedicle screw fixation in patients with bone softening caused by osteoporosis and metastatic tumor involvement: a clinical evaluation. Neurosurgery 61:531–537 discussion 537–538PubMedCrossRef
6.
go back to reference Halverson TL, Kelley LA, Thomas KA et al (1994) Effects of bone mineral density on pedicle screw fixation. Spine (Phila Pa 1976) 19:2415–2420CrossRef Halverson TL, Kelley LA, Thomas KA et al (1994) Effects of bone mineral density on pedicle screw fixation. Spine (Phila Pa 1976) 19:2415–2420CrossRef
7.
go back to reference Mclain RF, McKinley TO, Yerby SA et al (1997) The effect of bone quality on pedicle screw loading in axial instability. A synthetic model. Spine (Phila Pa 1976) 22:1454–1460CrossRef Mclain RF, McKinley TO, Yerby SA et al (1997) The effect of bone quality on pedicle screw loading in axial instability. A synthetic model. Spine (Phila Pa 1976) 22:1454–1460CrossRef
8.
go back to reference Reitman CA, Nguyen L, Fogel GR (2004) Biomechanical evaluation of relationship of screw pullout strength, insertional torque, and bone mineral density in the cervical spine. J Spinal Disord Tech 17:306–311PubMedCrossRef Reitman CA, Nguyen L, Fogel GR (2004) Biomechanical evaluation of relationship of screw pullout strength, insertional torque, and bone mineral density in the cervical spine. J Spinal Disord Tech 17:306–311PubMedCrossRef
9.
go back to reference Polly DW Jr, Orchowski JR, Ellenbogen RG (1998) Revision pedicle screws. Bigger, longer shims—what is best? Spine (Phila Pa 1976) 23:1374–1379CrossRef Polly DW Jr, Orchowski JR, Ellenbogen RG (1998) Revision pedicle screws. Bigger, longer shims—what is best? Spine (Phila Pa 1976) 23:1374–1379CrossRef
10.
go back to reference Brantley AG, Mayfield JK, Koeneman JB et al (1994) The effects of pedicle screw fit. An in vitro study. Spine (Phila Pa 1976) 19:1752–1758CrossRef Brantley AG, Mayfield JK, Koeneman JB et al (1994) The effects of pedicle screw fit. An in vitro study. Spine (Phila Pa 1976) 19:1752–1758CrossRef
11.
go back to reference Kiner DW, Wybo CD, Sterba W et al (2008) Biomechanical analysis of different techniques in revision spinal instrumentation: larger diameter screws versus cement augmentation. Spine (Phila Pa 1976) 33:2618–2622CrossRef Kiner DW, Wybo CD, Sterba W et al (2008) Biomechanical analysis of different techniques in revision spinal instrumentation: larger diameter screws versus cement augmentation. Spine (Phila Pa 1976) 33:2618–2622CrossRef
12.
go back to reference Wittenberg RH, Lee KS, Shea M et al (1993) Effect of screw diameter, insertion technique, and bone cement augmentation of pedicular screw fixation strength. Clin Orthop Relat Res 296:278–287PubMed Wittenberg RH, Lee KS, Shea M et al (1993) Effect of screw diameter, insertion technique, and bone cement augmentation of pedicular screw fixation strength. Clin Orthop Relat Res 296:278–287PubMed
13.
go back to reference Pfeifer BA, Krag MH, Johnson C (1994) Repair of failed transpedicle screw fixation-A biomechanical study comparing polymethylmethacrylate, milled bone, and matchstick bone reconstruction. Spine (Phila Pa 1976) 19:350–353CrossRef Pfeifer BA, Krag MH, Johnson C (1994) Repair of failed transpedicle screw fixation-A biomechanical study comparing polymethylmethacrylate, milled bone, and matchstick bone reconstruction. Spine (Phila Pa 1976) 19:350–353CrossRef
14.
go back to reference Sarzier JS, Evans AJ, Cahill DW (2002) Increased pedicle screw pull out strength with vertebroplasty augmentation in osteoporotic spines. J Neurosurg 96(3 Suppl):309–312PubMed Sarzier JS, Evans AJ, Cahill DW (2002) Increased pedicle screw pull out strength with vertebroplasty augmentation in osteoporotic spines. J Neurosurg 96(3 Suppl):309–312PubMed
15.
go back to reference Kayanja M, Evans K, Milks R et al (2006) The mechanics of polymethylmethacrylate augmentation. Clin Orthop Relat Res 443:124–130PubMedCrossRef Kayanja M, Evans K, Milks R et al (2006) The mechanics of polymethylmethacrylate augmentation. Clin Orthop Relat Res 443:124–130PubMedCrossRef
16.
go back to reference Hriano T, Hasegawa K, Washio T et al (1998) Fracture risk during pedicle screw insertion in osteoporotic spine. J Spinal Disord 11:493–497 Hriano T, Hasegawa K, Washio T et al (1998) Fracture risk during pedicle screw insertion in osteoporotic spine. J Spinal Disord 11:493–497
17.
go back to reference Lonstein JE, Denis F, Perra JH et al (1999) Complications associated with pedicle screws. J Bone Joint Surg 81:1519–1528PubMed Lonstein JE, Denis F, Perra JH et al (1999) Complications associated with pedicle screws. J Bone Joint Surg 81:1519–1528PubMed
18.
go back to reference Konno S, Olmaker K, Byrod G (1994) The European Spine Society Aero Med Prize 1994: acute thermal nerve root injury. Eur Spine J 3:299–302PubMedCrossRef Konno S, Olmaker K, Byrod G (1994) The European Spine Society Aero Med Prize 1994: acute thermal nerve root injury. Eur Spine J 3:299–302PubMedCrossRef
19.
go back to reference Lei W, Wu Z (2006) Biomechanical evaluation of an expansive pedicle screw in calf vertebrae. Eur Spine J 15:321–326PubMedCrossRef Lei W, Wu Z (2006) Biomechanical evaluation of an expansive pedicle screw in calf vertebrae. Eur Spine J 15:321–326PubMedCrossRef
20.
go back to reference Cook SD, Salkeld SL, Whitecloud TS 3rd et al (2000) Biomechanical evaluation and preliminary clinical experience with an expansive pedicle screw design. J Spinal Disord 13:230–236PubMedCrossRef Cook SD, Salkeld SL, Whitecloud TS 3rd et al (2000) Biomechanical evaluation and preliminary clinical experience with an expansive pedicle screw design. J Spinal Disord 13:230–236PubMedCrossRef
21.
go back to reference Cook SD, Salkeld SL, Stanley T et al (2004) Biomechanical study of pedicle screw fixation in severely osteoporotic bone. Spine J 4:402–408PubMedCrossRef Cook SD, Salkeld SL, Stanley T et al (2004) Biomechanical study of pedicle screw fixation in severely osteoporotic bone. Spine J 4:402–408PubMedCrossRef
22.
go back to reference Cook SD, Barbera J, Rubi M et al (2001) Lumbosacral fixation using expandable pedicle screws. An alternative in reoperation and osteoporosis. Spine J 1:109–114PubMedCrossRef Cook SD, Barbera J, Rubi M et al (2001) Lumbosacral fixation using expandable pedicle screws. An alternative in reoperation and osteoporosis. Spine J 1:109–114PubMedCrossRef
23.
go back to reference Burval DJ, McLain RF, Milks R et al (2007) Primary pedicle screw augmentation in osteoporotic lumbar vertebrae: biomechanical analysis of pedicle fixation strength. Spine (Phila Pa 1976) 32:1077–1083CrossRef Burval DJ, McLain RF, Milks R et al (2007) Primary pedicle screw augmentation in osteoporotic lumbar vertebrae: biomechanical analysis of pedicle fixation strength. Spine (Phila Pa 1976) 32:1077–1083CrossRef
24.
go back to reference Chang MC, Liu CL, Chen TH (2008) Polymethylmethacrylate augmentation of pedicle screw for osteoporotic spinal surgery: a novel technique. Spine (Phila Pa 1976) 33:E317–E324CrossRef Chang MC, Liu CL, Chen TH (2008) Polymethylmethacrylate augmentation of pedicle screw for osteoporotic spinal surgery: a novel technique. Spine (Phila Pa 1976) 33:E317–E324CrossRef
25.
go back to reference Moon BJ, Cho BY, Choi EY et al (2009) Polymethylmethacrylate-augmented screw fixation for stabilization of the osteoporotic spine: a three-year follow-up of 37 patients. J Korean Neurosurg Soc 46:305–311PubMedCrossRef Moon BJ, Cho BY, Choi EY et al (2009) Polymethylmethacrylate-augmented screw fixation for stabilization of the osteoporotic spine: a three-year follow-up of 37 patients. J Korean Neurosurg Soc 46:305–311PubMedCrossRef
26.
go back to reference Wan SY, Lei W, Wu ZX et al (2008) Micro-CT evaluation and histological analysis of screw-bone interface of expansive pedicle screw in osteoporotic sheep. Chin J Traumatol 11:72–77PubMed Wan SY, Lei W, Wu ZX et al (2008) Micro-CT evaluation and histological analysis of screw-bone interface of expansive pedicle screw in osteoporotic sheep. Chin J Traumatol 11:72–77PubMed
27.
go back to reference Leung KS, Siu WS, Li SF et al (2006) An in vitro optimized injectable calcium phosphate cement for augmenting screw fixation in osteopenic goats. J Biomed Mater Res B Appl Biomater 78:153–160PubMed Leung KS, Siu WS, Li SF et al (2006) An in vitro optimized injectable calcium phosphate cement for augmenting screw fixation in osteopenic goats. J Biomed Mater Res B Appl Biomater 78:153–160PubMed
28.
go back to reference Hashemi A, Bednar D, Ziada S et al (2009) Pullout strength of pedicle screws augmented with particulate calcium phosphate: an experimental study. Spine J 9:404–410PubMedCrossRef Hashemi A, Bednar D, Ziada S et al (2009) Pullout strength of pedicle screws augmented with particulate calcium phosphate: an experimental study. Spine J 9:404–410PubMedCrossRef
29.
go back to reference Derincek A, Wu C, Mehbod A et al (2006) Biomechanical comparison of anatomic trajectory pedicle screw versus injectable calcium sulfate graft-augmented pedicle screw for salvage in cadaveric thoracic bone. J Spinal Disord Tech 19:286–291PubMedCrossRef Derincek A, Wu C, Mehbod A et al (2006) Biomechanical comparison of anatomic trajectory pedicle screw versus injectable calcium sulfate graft-augmented pedicle screw for salvage in cadaveric thoracic bone. J Spinal Disord Tech 19:286–291PubMedCrossRef
30.
go back to reference Yi X, Wang Y, Lu H et al (2008) Augmentation of pedicle screw fixation strength using an injectable calcium sulfate cement: an in vivo study. Spine (Phila Pa 1976) 33:2503–2509CrossRef Yi X, Wang Y, Lu H et al (2008) Augmentation of pedicle screw fixation strength using an injectable calcium sulfate cement: an in vivo study. Spine (Phila Pa 1976) 33:2503–2509CrossRef
31.
go back to reference Bostan B, Esenkaya I, Gunes T et al (2009) A biomechanical comparison of polymethylmethacrylate- reinforced and expansive pedicle screws in pedicle-screw revisions. Acta Orthop Traumatol Turc 43:272–276PubMedCrossRef Bostan B, Esenkaya I, Gunes T et al (2009) A biomechanical comparison of polymethylmethacrylate- reinforced and expansive pedicle screws in pedicle-screw revisions. Acta Orthop Traumatol Turc 43:272–276PubMedCrossRef
Metadata
Title
Biomechanical comparison of different techniques in primary spinal surgery in osteoporotic cadaveric lumbar vertebrae: expansive pedicle screw versus polymethylmethacrylate-augmented pedicle screw
Authors
Da Liu
Zi-xiang Wu
Xian-ming Pan
Suo-chao Fu
Ming-xuan Gao
Lei Shi
Wei Lei
Publication date
01-09-2011
Publisher
Springer-Verlag
Published in
Archives of Orthopaedic and Trauma Surgery / Issue 9/2011
Print ISSN: 0936-8051
Electronic ISSN: 1434-3916
DOI
https://doi.org/10.1007/s00402-011-1290-9

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