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Journal of Cardiovascular Magnetic Resonance
Published in: Journal of Cardiovascular Magnetic Resonance 1/2012

Open Access 01-12-2012 | Poster presentation

Bio-imaging: late gadolinium enhancement in hypertrophic cardiomyopathy and its relation to novel biomarkers of fibrosis

Authors: Hassan Abdel-Aty, Hugo A Katus, Henning Steen, Stephanie Lehrke

Published in: Journal of Cardiovascular Magnetic Resonance | Special Issue 1/2012

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Excerpt

Late gadolinium enhancement (LGE) accurately detects myocardial fibrosis in hypertrophic cardiomyopathy (HCM), which has been recently shown to be an independent risk factor for cardiac events in this setting. Endoglin is an accessory protein for the TGF-β receptor, which stimulates myocardial fibrosis through modulating the response to Angiotensin II. We sought to explore the relationship between the myocardial fibrosis (tissue substrate) as identified by LGE and Endoglin (biomarker) in the setting of HCM. …
Metadata
Title
Bio-imaging: late gadolinium enhancement in hypertrophic cardiomyopathy and its relation to novel biomarkers of fibrosis
Authors
Hassan Abdel-Aty
Hugo A Katus
Henning Steen
Stephanie Lehrke
Publication date
01-12-2012
Publisher
BioMed Central
DOI
https://doi.org/10.1186/1532-429X-14-S1-P164

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