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Neurological Sciences
Published in: Neurological Sciences 7/2015

01-07-2015 | Letter to the Editor

Bilateral thalamic stroke due to nasal ephedrine and naphazoline use

Authors: Claudio Liguori, F. Garaci, A. Romigi, N. B. Mercuri, M. G. Marciani, F. Placidi

Published in: Neurological Sciences | Issue 7/2015

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Excerpt

Sympathomimetic drugs, like ephedrine or naphazoline, may be important stroke determinants [1]. In fact, cerebral vasoconstriction is often postulated as a possible mechanism of sympathomimetic drug-related cerebral infarction [2, 3]. Ephedrine and naphazoline are currently available and widely used over-the-counter as some cold and flu remedies, and considered by many consumers as relatively safe with few significant side effects. …
Literature
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Schaneberg BT, Crockett S, Bedir E, Khan IA (2003) The role of chemical fingerprinting: application to Ephedra. Phytochemistry 62(6):911–918PubMedCrossRef
2.
Bruno A, Nolte KB, Chapin J (1993) Stroke associated with ephedrine use. Neurology 43(7):1313–1316PubMedCrossRef
3.
Tark EB, Messe SR, Balucani C, Levine SR (2014) Intracerebral hemorrhage associated with oral phenylephrine use: a case report and review of the literature. J Stroke Cerebrovasc Dis 23(9):2296–2300PubMedCrossRef
4.
Costantino G, Ceriani E, Sandrone G, Montano N (2007) Ischemic stroke in a man with naphazoline abuse history. Am J Emerg Med 25(8):983.e1–983.e2CrossRef
5.
Teoh HL, Ahmad A, Yeo LL, Sharma VK et al (2010) Bilateral thalamic infarctions due to occlusion of artery of Percheron. J Neurol Sci 293(1–2):110–111PubMedCrossRef
Metadata
Title
Bilateral thalamic stroke due to nasal ephedrine and naphazoline use
Authors
Claudio Liguori
F. Garaci
A. Romigi
N. B. Mercuri
M. G. Marciani
F. Placidi
Publication date
01-07-2015
Publisher
Springer Milan
Published in
Neurological Sciences / Issue 7/2015
Print ISSN: 1590-1874
Electronic ISSN: 1590-3478
DOI
https://doi.org/10.1007/s10072-014-2030-z

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