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BMC Ophthalmology

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Open Access 01-12-2016 | Case report

Bilateral abducens nerve palsy in an infant case of fulminant acute disseminated encephalomyelitis: a case report

Authors: Zhiliang Yang, Guilian Sun

Published in: BMC Ophthalmology | Issue 1/2016

Abstract

Background

Sixth (abducens) nerve palsy (ANP) is far less frequent in children and has not been reported as a sign of acute disseminated encephalomyelitis (ADEM). We present an infant case of ADEM with bilateral abducens nerve palsy (BANP).

Case presentation

We report one case of BANP in a 15-month-old boy of fulminant ADEM. The patient underwent physical examinations and brain MRI scan three times during about six months follow-up. The patient had BANP and developmental regression when he regained consciousness from a coma, and the signs had persisted for 6-months.

Conclusions

BANP can be a symptom of ADEM.

Esposito S, Di Pietro GM, Madini B, Mastrolia MV, Rigante D. A spectrum of inflammation and demyelinization in acute disseminated encephalomyelitis (ADEM) of children. Autoimmun Rev. 2015;14(10):923–9.CrossRefPubMed

Mohsen H, Abu Zeinah GF, Elsotouhy AH, Mohamed K. Acute disseminated encephalomyelitis following infectious mononucleosis in a toddler. BMJ Case Rep. 2013; doi: 10.1136/bcr-2013-010048.

Merino P, Gómez de Liaño P, Villalobo JM, Franco G, Gómez de Liaño R. Etiology and treatment of pediatric sixth nerve palsy. J AAPOS. 2010;14(6):502–5.CrossRefPubMed

Rahmlow MR, Kantarci O. Fulminant demyelinating diseases. Neurohospitalist. 2013;3(2):81–91.CrossRefPubMedPubMedCentral

Murthy JM. Acute disseminated encephalomyelitis. Neurol India. 2002;50(3):238–43.PubMed

Murthy JM, Yangala R, Meena AK, Jaganmohan RJ. Acute disseminated encephalomyelitis: clinical and MRI study from South India. J Neurol Sci. 1999;165(2):133–8.CrossRefPubMed

Alexander M, Murthy JMK. Acute disseminated encephalomyelitis: treatment guidelines. Ann Indian Acad Neurol. 2011;14 Suppl 1:S60–4.CrossRefPubMedPubMedCentral

Krupp LB, Tardieu M, Amato MP, Banwell B, Chitnis T, Dale RC, et al. International pediatric multiple sclerosis study group criteria for pediatric multiple sclerosis and immune-mediated central nervous system demyelinating disorders: revisions to the 2007 definitions. Mult Scler. 2013;19(10):1261–7.CrossRefPubMed

İncecik F, Hergüner MÖ, Altunbaşak Ş. Acute disseminated encephalomyelitis: an evaluation of 15 cases in childhood. Turk J Pediatr. 2013;55(3):253–9.PubMed

10.

Tenembaum S, Chamoles N, Fejerman N. Acute disseminated encephalomyelitis: a long-term follow-up study of 84 pediatric patients. Neurology. 2002;59(8):1224–31.CrossRefPubMed

Title: Bilateral abducens nerve palsy in an infant case of fulminant acute disseminated encephalomyelitis: a case report
Authors: Zhiliang Yang
Guilian Sun
Publication date: 01-12-2016
Publisher: BioMed Central
Published in: BMC Ophthalmology / Issue 1/2016
Electronic ISSN: 1471-2415
DOI: https://doi.org/10.1186/s12886-016-0365-3

At a glance: The STEP trials

Springer Medicine

Bilateral abducens nerve palsy in an infant case of fulminant acute disseminated encephalomyelitis: a case report

Abstract

Background

Case presentation

Conclusions

At a glance: The STEP trials

Springer Medicine

Abstract

Background

Case presentation

Conclusions

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