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Published in: Clinical and Translational Oncology 10/2014

01-10-2014 | Correspondence

Bevacizumab in advanced cervical cancer

Authors: P. J. Vlachostergios, C. N. Papandreou

Published in: Clinical and Translational Oncology | Issue 10/2014

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Excerpt

Angiogenesis and hypoxia have been proven to be the established players in cervical cancer progression, and relevant markers, including vascular endothelial growth factor, carbonic anhydrase 9 and hypoxia-inducible factor-1α was proven to be associated with poor prognosis in cervical cancer patients primarily treated with chemoradiation [1]. …
Literature
1.
go back to reference Gadducci A, Guerrieri ME, Greco C. Tissue biomarkers as prognostic variables of cervical cancer. Crit Rev Oncol Hematol. 2013;86:104–29.PubMedCrossRef Gadducci A, Guerrieri ME, Greco C. Tissue biomarkers as prognostic variables of cervical cancer. Crit Rev Oncol Hematol. 2013;86:104–29.PubMedCrossRef
2.
go back to reference Tewari KS, Sill MW, Long HJ 3rd, Penson RT, Huang H, Ramondetta LM, et al. Improved survival with bevacizumab in advanced cervical cancer. N Engl J Med. 2014;370:734–43.PubMedCrossRefPubMedCentral Tewari KS, Sill MW, Long HJ 3rd, Penson RT, Huang H, Ramondetta LM, et al. Improved survival with bevacizumab in advanced cervical cancer. N Engl J Med. 2014;370:734–43.PubMedCrossRefPubMedCentral
3.
go back to reference Wolfson AH, Varia MA, Moore D, Rao GG, Gaffney DK, Erickson-Wittmann BA, et al. ACR Appropriateness Criteria® role of adjuvant therapy in the management of early stage cervical cancer. Gynecol Oncol. 2012;125:256–62.PubMedCrossRef Wolfson AH, Varia MA, Moore D, Rao GG, Gaffney DK, Erickson-Wittmann BA, et al. ACR Appropriateness Criteria® role of adjuvant therapy in the management of early stage cervical cancer. Gynecol Oncol. 2012;125:256–62.PubMedCrossRef
4.
go back to reference Schefter T, Winter K, Kwon JS, Stuhr K, Balaraj K, Yaremko BP, et al. RTOG 0417: efficacy of bevacizumab in combination with definitive radiation therapy and cisplatin chemotherapy in untreated patients with locally advanced cervical carcinoma. Int J Radiat Oncol Biol Phys. 2014;88:101–5.PubMedCrossRef Schefter T, Winter K, Kwon JS, Stuhr K, Balaraj K, Yaremko BP, et al. RTOG 0417: efficacy of bevacizumab in combination with definitive radiation therapy and cisplatin chemotherapy in untreated patients with locally advanced cervical carcinoma. Int J Radiat Oncol Biol Phys. 2014;88:101–5.PubMedCrossRef
5.
go back to reference Zighelboim I, Wright JD, Gao F, Case AS, Massad LS, Mutch DG, et al. Multicenter phase II trial of topotecan, cisplatin and bevacizumab for recurrent or persistent cervical cancer. Gynecol Oncol. 2013;130:64–8.PubMedCrossRef Zighelboim I, Wright JD, Gao F, Case AS, Massad LS, Mutch DG, et al. Multicenter phase II trial of topotecan, cisplatin and bevacizumab for recurrent or persistent cervical cancer. Gynecol Oncol. 2013;130:64–8.PubMedCrossRef
Metadata
Title
Bevacizumab in advanced cervical cancer
Authors
P. J. Vlachostergios
C. N. Papandreou
Publication date
01-10-2014
Publisher
Springer Milan
Published in
Clinical and Translational Oncology / Issue 10/2014
Print ISSN: 1699-048X
Electronic ISSN: 1699-3055
DOI
https://doi.org/10.1007/s12094-014-1205-7

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