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BMC Urology

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Open Access 01-12-2021 | Benign Prostatic Hypertrophy | Research

Modified bladder outlet obstruction index for powerful efficacy prediction of transurethral resection of prostate with benign prostatic hyperplasia

Authors: Hongming Liu, Ye Tian, Guangheng Luo, Zhiyong Su, Yong Ban, Zhen Wang, Zhaolin Sun

Published in: BMC Urology | Issue 1/2021

Abstract

Background

The correlation between modified bladder outlet obstruction index (MBOOI) and surgical efficacy still remains unknown. The purpose of the study was to investigate the clinical value of the MBOOI and its use in predicting surgical efficacy in men receiving transurethral resection of the prostate (TURP).

Methods

A total of 403 patients with benign prostate hyperplasia (BPH) were included in this study. The International Prostate Symptom Score (IPSS), quality of life (QoL) index, transrectal ultrasonography, and pressure flow study were conducted for all patients. The bladder outlet obstruction index (BOOI) (P_detQ_max–2Q_max) and MBOOI (P_ves–2Q_max) were calculated. All patients underwent TURP, and surgical efficacy was accessed by the improvements in IPSS, QoL, and Q_max 6 months after surgery. The association between surgical efficacy and baseline factors was statistically analyzed.

Results

A comparison of effective and ineffective groups based on the overall efficacy showed that significant differences were observed in PSA, P_ves, P_detQ_max, P_abd, BOOI, MBOOI, TZV, TZI, IPSS-t, IPSS-v, IPSS-s, Q_max, and PVR at baseline (p < 0.05). Binary logistic regression analysis suggested that MBOOI was the only baseline parameter correlated with the improvements in IPSS, QoL, Q_max, and the overall efficacy. Additionally, the ROC analysis further verified that MBOOI was more optimal than BOOI, TZV and TZI in predicting the surgical efficacy.

Conclusion

Although both MBOOI and BOOI can predict the clinical symptoms and surgical efficacy of BPH patients to a certain extent, however, compared to BOOI, MBOOI may be a more useful factor that can be used to predict the surgical efficacy of TURP.

Trial registration retrospectively registered.

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Title: Modified bladder outlet obstruction index for powerful efficacy prediction of transurethral resection of prostate with benign prostatic hyperplasia
Authors: Hongming Liu
Ye Tian
Guangheng Luo
Zhiyong Su
Yong Ban
Zhen Wang
Zhaolin Sun
Publication date: 01-12-2021
Publisher: BioMed Central
Keywords: Benign Prostatic Hypertrophy
Benign Prostatic Hypertrophy
Transurethral Prostate Resection
Published in: BMC Urology / Issue 1/2021
Electronic ISSN: 1471-2490
DOI: https://doi.org/10.1186/s12894-021-00937-x

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Modified bladder outlet obstruction index for powerful efficacy prediction of transurethral resection of prostate with benign prostatic hyperplasia

Abstract

Background

Methods

Results

Conclusion

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Abstract

Background

Methods

Results

Conclusion

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