Skip to main content
Top
Published in: African Journal of Urology 1/2021

Open Access 01-12-2021 | Benign Prostatic Hypertrophy | Original Research

Correlation of prostate volume with severity of lower urinary tract symptoms as measured by international prostate symptoms score and maximum urine flow rate among patients with benign prostatic hyperplasia

Authors: Mudi Awaisu, Muhammed Ahmed, Ahmad Tijjani Lawal, Abdullahi Sudi, Musliu Adetola Tolani, Nasir Oyelowo, Muhammad Salihu Muhammad, Ahmad Bello, Hussaini Yusuf Maitama

Published in: African Journal of Urology | Issue 1/2021

Login to get access

Abstract

Background

The aim of the study is to find the correlation between the prostate volume and severity of lower urinary tract symptoms (LUTS) as measured by international prostate symptoms score and maximum urine flow rate among patients with benign prostatic hyperplasia (BPH).

Methods

The study was a prospective correlational study conducted between June 2016 and November 2017. A total of 290 patients who presented with LUTS suggestive of BPH and satisfied the inclusion criteria were consecutively recruited. Clinical evaluation including digital rectal examination of the prostate was done. Symptoms severity was assessed using the self-administered international prostate symptoms score (IPSS) questionnaire. Prostate volume was determined by transrectal ultrasound scan, and the urine flow rate was measured using uroflowmeter. Data were analyzed using SPSS version 20.0, and p value < 0.05 was taken to be statistically significant.

Results

The mean age of the patients was 64.22 ± 9.04 years with a range of 40 to 95 years. Most of the patients had moderate symptoms (55%) on IPSS with the mean IPSS value of 16.41 ± 7.43. The mean Qmax value was 16.55 ± 7.41 ml/s, and the median prostate volume (IQR) was 45.05 (35, 59). There was a positive significant correlation between prostate volume and IPSS (r = 0.179, p = 0.002) and a negative significant correlation between prostate volume and Qmax (r = − 0.176, p = 0.003).

Conclusion

This study showed a significant correlation between the prostate volume and IPSS, and also between prostate volume and maximum flow rate (Qmax).
Literature
1.
go back to reference Lee C, Kozlowski J, Grayhack J (1997) Intrinsic and extrinsic factors controlling benign prostatic growth. Prostate 31:131–138CrossRef Lee C, Kozlowski J, Grayhack J (1997) Intrinsic and extrinsic factors controlling benign prostatic growth. Prostate 31:131–138CrossRef
2.
go back to reference Hoke GP, Mc Williams G (2008) Epidemiology of benign prostatic hyperplasia and comorbidities in racial and ethnic minority populations. Am J Med 121:S3–10CrossRef Hoke GP, Mc Williams G (2008) Epidemiology of benign prostatic hyperplasia and comorbidities in racial and ethnic minority populations. Am J Med 121:S3–10CrossRef
3.
go back to reference Movsas S (1966) Prostatic obstruction in the African and Asiatic. Br J Surg 53:538–543CrossRef Movsas S (1966) Prostatic obstruction in the African and Asiatic. Br J Surg 53:538–543CrossRef
4.
go back to reference Garraway WM, Collins GN, Lee RJ (1991) High prevalence of benign prostatic hypertrophy in the community. Lancet 338:469–471CrossRef Garraway WM, Collins GN, Lee RJ (1991) High prevalence of benign prostatic hypertrophy in the community. Lancet 338:469–471CrossRef
5.
go back to reference Tsang KK, Garraway WM (1993) Impact of benign prostatic hyperplasia on general well-being of men. Prostate 23:1–7CrossRef Tsang KK, Garraway WM (1993) Impact of benign prostatic hyperplasia on general well-being of men. Prostate 23:1–7CrossRef
6.
go back to reference Mc Connell JD (1994) Why pressure-flow studies should beoptional and not mandatory studies for evaluating men with benign prostatic hyperplasia. Urology 44:156–158CrossRef Mc Connell JD (1994) Why pressure-flow studies should beoptional and not mandatory studies for evaluating men with benign prostatic hyperplasia. Urology 44:156–158CrossRef
7.
go back to reference Ezz el Din K, Kiemeney LA, de Wildt MJ, Debruyne FM, de la Rosette JJ (1996) Correlation between uroflowmetry, prostate volume, postvoid residue, and lower urinary tract symptoms as measured by the International Prostate Symptom Score. Urology 48:393–397CrossRef Ezz el Din K, Kiemeney LA, de Wildt MJ, Debruyne FM, de la Rosette JJ (1996) Correlation between uroflowmetry, prostate volume, postvoid residue, and lower urinary tract symptoms as measured by the International Prostate Symptom Score. Urology 48:393–397CrossRef
8.
go back to reference Watanabe H, Kaiho H, Tanaka M, Terasawa Y (1971) Diagnostic application of ultrasonotomography to the prostate. Invest Urol 8:548–559PubMed Watanabe H, Kaiho H, Tanaka M, Terasawa Y (1971) Diagnostic application of ultrasonotomography to the prostate. Invest Urol 8:548–559PubMed
9.
go back to reference Jian-ye W, Ming L, Yao-guang Z, Ping Z, Qiang D, Jian H et al (2008) Relationship between lower urinary tract symptoms and objective measures of benign prostatic hyperplasia; a chinese survey. Chin Med J 121:2042–2045CrossRef Jian-ye W, Ming L, Yao-guang Z, Ping Z, Qiang D, Jian H et al (2008) Relationship between lower urinary tract symptoms and objective measures of benign prostatic hyperplasia; a chinese survey. Chin Med J 121:2042–2045CrossRef
10.
go back to reference Cakiroglu B (2013) The correlation of symptoms severity and objective measures in patients with lower urinary tract symptoms. Clin Med Res 2:135–139CrossRef Cakiroglu B (2013) The correlation of symptoms severity and objective measures in patients with lower urinary tract symptoms. Clin Med Res 2:135–139CrossRef
11.
go back to reference Agrawal CS, Chalise PR, Bhandari BB (2008) Correlation of prostate volume with international prostate symptom score and quality of life in men with benign prostatic hyperplasia. Nepal Med Coll J 10:104–107PubMed Agrawal CS, Chalise PR, Bhandari BB (2008) Correlation of prostate volume with international prostate symptom score and quality of life in men with benign prostatic hyperplasia. Nepal Med Coll J 10:104–107PubMed
13.
go back to reference Badmus TA, Asaleye CM, Badmus SA, Takure AO, Ibrahim MH, Arowolo OA (2012) Benign prostate hyperplasia: average volume in southwestern Nigerians and correlation with anthropometrics. Niger Postgrad Med J 19:15–18PubMed Badmus TA, Asaleye CM, Badmus SA, Takure AO, Ibrahim MH, Arowolo OA (2012) Benign prostate hyperplasia: average volume in southwestern Nigerians and correlation with anthropometrics. Niger Postgrad Med J 19:15–18PubMed
14.
go back to reference Ojewola RW, Oridota ES, Balogun OS, Alabi TO, Ajayi AI, Olajide TA et al (2017) Prevalence of clinical benign prostatic hyperplasia amongst community-dwelling men in a South-Western Nigerian rural setting: a cross-sectional study. Afr J Urol 23:109–115CrossRef Ojewola RW, Oridota ES, Balogun OS, Alabi TO, Ajayi AI, Olajide TA et al (2017) Prevalence of clinical benign prostatic hyperplasia amongst community-dwelling men in a South-Western Nigerian rural setting: a cross-sectional study. Afr J Urol 23:109–115CrossRef
15.
go back to reference Udeh EI (2013) The relationship between prostate volume and international prostate symptom score in Africans with benign prostatic hyperplasia. Niger J Med 10:120–125 Udeh EI (2013) The relationship between prostate volume and international prostate symptom score in Africans with benign prostatic hyperplasia. Niger J Med 10:120–125
16.
go back to reference Kenneth A, Francis A, Christian GK, Ferguson LE, Emmanuel A, Benjamin TF et al (2016) Lower urinary tract symptoms suggestive of benign prostatic hyperplasia among Ghanaian men: a hospital-based cross-sectional prospective study. Int J Res Med Sci 4:3905–3911CrossRef Kenneth A, Francis A, Christian GK, Ferguson LE, Emmanuel A, Benjamin TF et al (2016) Lower urinary tract symptoms suggestive of benign prostatic hyperplasia among Ghanaian men: a hospital-based cross-sectional prospective study. Int J Res Med Sci 4:3905–3911CrossRef
17.
go back to reference Ofoha CG, Shu’aibu SI, Akpayak IC, Dakum NK, Ramyil VM (2013) Relationship between prostate volume and ipss in african men with prostate disease. JOS J Med 9:16–19 Ofoha CG, Shu’aibu SI, Akpayak IC, Dakum NK, Ramyil VM (2013) Relationship between prostate volume and ipss in african men with prostate disease. JOS J Med 9:16–19
18.
go back to reference Mohammed A, Bello A, Maitama HY, Ajibola HO, Lawal AT et al (2014) Determination of prostatic volume and characteristics by transrectal ultrasound among patients with lower urinary tract symptoms. Arch Int Surg 4:30–35CrossRef Mohammed A, Bello A, Maitama HY, Ajibola HO, Lawal AT et al (2014) Determination of prostatic volume and characteristics by transrectal ultrasound among patients with lower urinary tract symptoms. Arch Int Surg 4:30–35CrossRef
19.
go back to reference Gnyawali D, Sharma U (2014) Correlation of prostate volume with ‘International Prostate Symptom Score’ and ‘Benign Prostatic Hyperplasia-Impact Index’ in benign prostatic hyperplasia. JSSN 17:1–5 Gnyawali D, Sharma U (2014) Correlation of prostate volume with ‘International Prostate Symptom Score’ and ‘Benign Prostatic Hyperplasia-Impact Index’ in benign prostatic hyperplasia. JSSN 17:1–5
20.
go back to reference Bosch JL, Hop WC, Kirkels WJ, Schroder FH (1995) The International Prostate Symptom Score in a community-based sample of men between 55 and 74 years of age_prevalence and correlation of symptoms. Br J Urol 75:622–630CrossRef Bosch JL, Hop WC, Kirkels WJ, Schroder FH (1995) The International Prostate Symptom Score in a community-based sample of men between 55 and 74 years of age_prevalence and correlation of symptoms. Br J Urol 75:622–630CrossRef
21.
go back to reference Sciarra A, D’Eramo G, Casale P, Loreto A, Buscarini M, Di Nicola S et al (1998) Relationship among symptom score, prostate volume, and urinary flow rates in 543 patients with and without benign prostatic hyperplasia. Prostate 34:121–128CrossRef Sciarra A, D’Eramo G, Casale P, Loreto A, Buscarini M, Di Nicola S et al (1998) Relationship among symptom score, prostate volume, and urinary flow rates in 543 patients with and without benign prostatic hyperplasia. Prostate 34:121–128CrossRef
22.
go back to reference Barry MJ, Fowler FJ, O’Leary MP, Bruskewitz RC, Holtgrewe HL, Mebust WK et al (1992) The American Urological Association symptom index for BPH. J Urol 5:1549–1557CrossRef Barry MJ, Fowler FJ, O’Leary MP, Bruskewitz RC, Holtgrewe HL, Mebust WK et al (1992) The American Urological Association symptom index for BPH. J Urol 5:1549–1557CrossRef
23.
go back to reference Ogwuche NI, Dakum NK, Amu CO, Dung ED, Udeh E, Ramyil VM (2013) Problems with administration of international prostate symptom score in a developing community. Ann Afr Med 12:171–173CrossRef Ogwuche NI, Dakum NK, Amu CO, Dung ED, Udeh E, Ramyil VM (2013) Problems with administration of international prostate symptom score in a developing community. Ann Afr Med 12:171–173CrossRef
24.
go back to reference Oranusi CK, Nwofor AE, Mbonu O (2017) Correlation between International Prostate Symptom Score and Uroflowmetry in Patients with Benign Prostatic Hyperplasia. Niger J Clin Pract 20:454–458PubMed Oranusi CK, Nwofor AE, Mbonu O (2017) Correlation between International Prostate Symptom Score and Uroflowmetry in Patients with Benign Prostatic Hyperplasia. Niger J Clin Pract 20:454–458PubMed
Metadata
Title
Correlation of prostate volume with severity of lower urinary tract symptoms as measured by international prostate symptoms score and maximum urine flow rate among patients with benign prostatic hyperplasia
Authors
Mudi Awaisu
Muhammed Ahmed
Ahmad Tijjani Lawal
Abdullahi Sudi
Musliu Adetola Tolani
Nasir Oyelowo
Muhammad Salihu Muhammad
Ahmad Bello
Hussaini Yusuf Maitama
Publication date
01-12-2021
Publisher
Springer Berlin Heidelberg
Published in
African Journal of Urology / Issue 1/2021
Print ISSN: 1110-5704
Electronic ISSN: 1961-9987
DOI
https://doi.org/10.1186/s12301-021-00122-4

Other articles of this Issue 1/2021

African Journal of Urology 1/2021 Go to the issue