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01-03-2016 | Review Article

Benign and malignant tumors of the foot and ankle

Authors: Adam D. Singer, Abhijit Datir, Jonathan Tresley, Travis Langley, Paul D. Clifford, Jean Jose, Ty K. Subhawong

Published in: Skeletal Radiology | Issue 3/2016

Abstract

Pain and focal masses in the foot and ankle are frequently encountered and often initiate a workup including imaging. It is important to differentiate benign lesions from aggressive benign or malignant lesions. In this review, multiple examples of osseous and soft tissue tumors of the foot and ankle will be presented. Additionally, the compartmental anatomy of the foot and ankle will be discussed in terms of its relevance for percutaneous biopsy planning and eventual surgery. Finally, a general overview of the surgical management of benign, benign aggressive and malignant tumors of the foot and ankle will be discussed.

Wedmore I, Young S, Franklin J. Emerg Med Clin North Am. 2015;33(2):363–96.PubMedCrossRef

Burge AJ, Gold SL, Potter HG. Sports Health. 2012;4(6):518–34.PubMedPubMedCentralCrossRef

Van Hul E, Vanhoenacker F, Van Dyck P, De Schepper A, Parizel PM. Pseudotumoural soft tissue lesions of the foot and ankle: a pictorial review. Insights Imaging. 2011;2(4):439–52. PMC3259410.PubMedPubMedCentralCrossRef

Bakotic BW. Tumors of the soft tissue of the lower extremity. In: Principles and practice of podiatric medicine. Brooklandville, MD: Data Trace; 2006. p. 1–55.

Goodwin DW, Salonen DC, Yu JS, Brossmann J, Trudell DJ, Resnick DL. Plantar compartments of the foot: MR appearance in cadavers and diabetic patients. Radiology. 1995;196(3):623–30.PubMedCrossRef

Anderson MW, Temple HT, Dussault RG, Kaplan PA. Compartmental anatomy: relevance to staging and biopsy of musculoskeletal tumors. AJR Am J Roentgenol. 1999;173:1663–71.PubMedCrossRef

Ledermann HP, Morrison WB, Schweitzer ME. Is soft-tissue inflammation in pedal infection contained by fascial planes? MR analysis of compartmental involvement in 115 feet. AJR Am J Roentgenol. 2002;178(3):605–12.PubMedCrossRef

Mannem RR, Mautz AP, Baynes KE, Zambrano EV, King DM. AIRP best cases in radiologic-pathologic correlation: intraosseous lipoma. Radiographics. 2012;32(5):1523–8.PubMedCrossRef

Kumar R, Matasar K, Stansberry S, Shirkhoda A, David R, Madewell JE, et al. The calcaneus: normal and abnormal. Radiographics. 1991;11(3):415–40.PubMedCrossRef

10.

Llauger J, Palmer J, Monill JM, Franquet T, Bagué S, Rosón N. MR imaging of benign soft-tissue masses of the foot and ankle. Radiographics. 1998;18(6):1481–98.PubMedCrossRef

11.

Baek HJ, Lee SJ, Cho KH, Choo HJ, Lee SM, Lee YH, et al. Subungual tumors: clinicopathologic correlation with US and MR imaging findings. Radiographics. 2010;30(6):1621–36.PubMedCrossRef

12.

Murphey MD, Flemming DJ, Boyea SR, Bojescul JA, Sweet DE, Temple HT. Enchondroma versus chondrosarcoma in the appendicular skeleton: differentiating features. Radiographics. 1998;18(5):1213–37.PubMedCrossRef

13.

Joseph J, Ritchie D, MacDuff E, Mahendra A. Bizarre parosteal osteochondromatous proliferation: a locally aggressive benign tumor. Clin Orthop Relat Res. 2011;469(7):2019–27.PubMedPubMedCentralCrossRef

14.

Holmes C, Choksi P, Wrobel JS. Bizarre parosteal osteochondromatous proliferation: a novel case report of recurrence in the toe. J Am Podiatr Med Assoc. 2015;105(1):80–4.PubMedCrossRef

15.

Yang J, Tian W, Zhu X, Wang J. Chondroblastoma in the long bone diaphysis: a report of two cases with literature review. Chin J Cancer. 2012;31(5):257–64.PubMedPubMedCentralCrossRef

16.

Birch PJ, Buchanan R, Golding P, Pringle JA. Chondroblastoma of the rib with widespread bone metastases. Histopathology. 1994;25(6):583–5.PubMedCrossRef

17.

Zhang K, Gao Y, Dai H, Zhang S, Li G, Yu B. Chondroblastoma of the talus: a case report and literature review. J Foot Ankle Surg. 2012;51(2):262–5.PubMedCrossRef

18.

Tan H, Yan M, Yue B, Zeng Y, Wang Y. Chondroblastoma of the patella with aneurysmal bone cyst. Orthopedics. 2014;37(1):e87–91.PubMedCrossRef

19.

Chakarun CJ, Forrester DM, Gottsegen CJ, Patel DB, White EA, Matcuk Jr GR. Giant cell tumor of bone: review, mimics, and new developments in treatment. Radiographics. 2013;33(1):197–211.PubMedCrossRef

20.

Healey JH, Turnbull ADM, Miedema B, Lane JM. Acrometastases: a study of twenty-nine patients with osseous involvement of the hands and feet. J Bone Joint Surg Am. 1986;68:743–6.PubMed

21.

Olsen KI, Stacy GS, Montag A. Soft-tissue cavernous hemangioma. Radiographics. 2004;24(3):849–54.PubMedCrossRef

22.

Murphey MD, Rhee JH, Lewis RB, Fanburg-Smith JC, Flemming DJ, Walker EA. Radiographics. 2008;28(5):1493–518.PubMedCrossRef

23.

Dasgupta R, Fishman SJ. ISSVA classification. Semin Pediatr Surg. 2014;23(4):158–61.PubMedCrossRef

24.

Munksgaard PS, Salkus G, Iyer VV, Fisker RV. Mazabraud’s syndrome: case report and literature review. Acta Radiol Short Rep. 2013;31:2(4).

25.

Bancroft LW, Kransdorf MJ, Menke DM, O’Connor MI, Foster WC. Intramuscular myxoma: characteristic MR imaging features. AJR Am J Roentgenol. 2002;178(5):1255–9.PubMedCrossRef

26.

Gavriilidis P, Balis G, Giannouli A, Nikolaidou A. Intramuscular myxoma of the Soleus muscle: a rare tumor in an unusual location. Am J Case Rep. 2014;15:49–51.PubMedPubMedCentralCrossRef

27.

Bermejo A, De Bustamante TD, Martinez A, Carrera R, Zabía E, Manjón P. MR imaging in the evaluation of cystic-appearing soft-tissue masses of the extremities. Radiographics. 2013;33(3):833–55.PubMedCrossRef

28.

Murphey MD, Smith WS, Smith SE, Kransdorf MJ, Temple HT. From the archives of the AFIP. Imaging of musculoskeletal neurogenic tumors: radiologic-pathologic correlation. Radiographics. 1999;19(5):1253–80.PubMedCrossRef

29.

Hammas N, Badioui I, Znati K, Benlemlih A, Chbani L, et al. Dermatofibrosarcoma protuberans: report of 27 cases and review of the literature. Pan Afr Med J. 2014;18:280.PubMedPubMedCentralCrossRef

30.

Beaman FD, Kransdorf MJ, Andrews TR, Murphey MD, Arcara LK, Keeling JH. Superficial soft-tissue masses: analysis, diagnosis, and differential considerations. Radiographics. 2007;27(2):509–23.PubMedCrossRef

31.

Mendenhall WM, Zlotecki RA, Scarborough MT. Dermatofibrosarcoma protuberans. Cancer. 2004;101(11):2503–8.PubMedCrossRef

32.

Porter C, Vincetic A, Saleh ME, Goldstein H. Pigmented dermatofibrosarcoma protuberans of the foot with fibrosarcomatous changes: a review and case presentation. J Foot Ankle Surg. 2002;41(3):186–91.PubMedCrossRef

33.

Vandeweyer E, Deraemaecker R, Somerhausen ND, Geledan L, Gebhart M. Bednar tumor of the foot: a case report. Foot Ankle Int. 2001;22(4):339–41.PubMed

34.

Linda DD, Harish S, Alowami S, DeNardi F, Deheshi BM. Radiology-pathology conference: cutaneous angiosarcoma of the leg. Clin Imaging. 2013;37(3):602–7.PubMedCrossRef

35.

Murphey MD, Gibson MS, Jennings BT, Crespo-Rodríguez AM, Fanburg-Smith J, Gajewski DA. From the archives of the AFIP: imaging of synovial sarcoma with radiologic-pathologic correlation. Radiographics. 2006;26(5):1543–65.PubMedCrossRef

36.

Monaco SJ, Pearson K, Wukich DK. Squamous cell carcinoma with chronic osteomyelitis: a case report. Foot Ankle Spec. 2015.

37.

Smith J, Mello LF, Nogueira Neto NC, Meohas W, Pinto LW, et al. Malignancy in chronic ulcers and scars of the leg (Marjolin’s ulcer): a study of 21 patients. Skelet Radiol. 2001;30(6):331–7.CrossRef

38.

Murphey MD, Arcara LK, Fanburg-Smith J. From the archives of the AFIP: imaging of musculoskeletal liposarcoma with radiologic-pathologic correlation. Radiographics. 2005;25(5):1371–95.PubMedCrossRef

39.

Di Giandomenico S, Frapolli R, Bello E, Uboldi S, Licandro SA, et al. Mode of action of trabectedin in myxoid liposarcomas. Oncogene. 2014;33(44):5201–10.PubMedCrossRef

40.

Liu PT, Valadez SD, Chivers FS, Roberts CC, Beauchamp CP. Anatomically based guidelines for core needle biopsy of bone tumors: implications for limb-sparing surgery. Radiographics. 2007;27(1):189–205.PubMedCrossRef

41.

Espinosa LA, Jamadar DA, Jacobson JA, DeMaeseneer MO, Ebrahim FS, et al. CT-guided biopsy of bone: a radiologist’s perspective. AJR Am J Roentgenol. 2008;190(5):W283–9.PubMedCrossRef

42.

Toomayan GA, Robertson F, Major NM. Lower extremity compartmental anatomy: clinical relevance to radiologists. Skelet Radiol. 2005;34(6):307–13.CrossRef

43.

UyBico SJ, Motamedi K, Omura MC, Nelson SD, Eilber FC, et al. Relevance of compartmental anatomic guidelines for biopsy of musculoskeletal tumors: retrospective review of 363 biopsies over a 6-year period. J Vasc Interv Radiol. 2012;23(4):511–8. 518.e1-2.PubMedCrossRef

44.

Saghieh S, Masrouha KZ, Musallam KM, Mahfouz R, Abboud M, et al. The risk of local recurrence along the core-needle biopsy tract in patients with bone sarcomas. Iowa Orthop J. 2010;30:80–3.PubMedPubMedCentral

45.

Wang DT, Dubois M, Tutton SM. Complications in musculoskeletal intervention: important considerations. Semin Interv Radiol. 2015;32(2):163–73.CrossRef

46.

Davies NM, Livesley PJ, Cannon SR. Recurrence of an osteosarcoma in a needle biopsy track. J Bone Joint Surg (Br). 1993;75(6):977–8.

47.

Schwartz HS, Spengler DM. Needle tract recurrences after closed biopsy for sarcoma: three cases and review of the literature. Ann Surg Oncol. 1997;4(3):228–36.PubMedCrossRef

48.

Iemsawatdikul K, Gooding CA, Twomey EL, Kim GE, Goldsby RE, et al. Seeding of osteosarcoma in the biopsy tract of a patient with multifocal osteosarcoma. Pediatr Radiol. 2005;35(7):717–21.PubMedCrossRef

49.

Hidai H, Sakuramoto T, Miura T, Nakahashi M, Kikyo S. Needle tract seeding following puncture of retroperitoneal liposarcoma. Eur Urol. 1983;9(6):368–9.PubMed

50.

Rauh MA, Duquin TR, McGrath BE, Mindell ER. Spread of squamous cell carcinoma from the thumb to the small finger via the flexor tendon sheaths. J Hand Surg [Am]. 2009;34(9):1709–13.CrossRef

51.

Kujak JL, Liu PT, Johnson GB, Callstrom MR. Early experience with percutaneous cryoablation of extra-abdominal desmoid tumors. Skelet Radiol. 2010;39(2):175–82.CrossRef

52.

Chao AH, Mayerson JL, Chandawarkar R, Scharschmidt TJ. Surgical management of soft tissue sarcomas: extremity sarcomas. J Surg Oncol. 2015;111(5):540–5.PubMedCrossRef

Title: Benign and malignant tumors of the foot and ankle
Authors: Adam D. Singer
Abhijit Datir
Jonathan Tresley
Travis Langley
Paul D. Clifford
Jean Jose
Ty K. Subhawong
Publication date: 01-03-2016
Publisher: Springer Berlin Heidelberg
Published in: Skeletal Radiology / Issue 3/2016
Print ISSN: 0364-2348
Electronic ISSN: 1432-2161
DOI: https://doi.org/10.1007/s00256-015-2278-2

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Benign and malignant tumors of the foot and ankle

Abstract

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