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Journal of Medical Case Reports

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Open Access 01-12-2018 | Case report

Bartter syndrome-like phenotype in a patient with diabetes: a case report

Authors: Chamara Dalugama, Manoji Pathirage, S. A. M. Kularatne

Published in: Journal of Medical Case Reports | Issue 1/2018

Abstract

Background

Bartter’s syndrome is a rare genetic tubulopathy affecting the loop of Henle leading to salt wasting. It is commonly seen in utero or in early neonatal period. Rare cases of acquired Bartter’s syndrome are reported in association with infections like tuberculosis, granulomatous conditions like sarcoidosis, autoimmune diseases, and drugs. The mainstay of management includes potassium, calcium, and magnesium supplementation.

Case presentation

We report the case of a 62-year-old Sri Lankan Sinhalese man with diabetes and hypertension presenting with generalized weakness with clinical evidence of proximal myopathy. He was severely hypokalemic with high urinary potassium excretion and hypochloremic metabolic alkalosis. He poorly responded to intravenously administered potassium supplements. A diagnosis of idiopathic Bartter-like phenotype was made. He responded well to spironolactone and indomethacin.

Conclusions

Patients presenting with body weakness need serum potassium estimation. Acquired Bartter’s syndrome although rare, should be ruled out in those with hypokalemia and metabolic alkalosis with increased urinary potassium loss with poor response to potassium replacement.

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Title: Bartter syndrome-like phenotype in a patient with diabetes: a case report
Authors: Chamara Dalugama
Manoji Pathirage
S. A. M. Kularatne
Publication date: 01-12-2018
Publisher: BioMed Central
Published in: Journal of Medical Case Reports / Issue 1/2018
Electronic ISSN: 1752-1947
DOI: https://doi.org/10.1186/s13256-018-1752-6

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Bartter syndrome-like phenotype in a patient with diabetes: a case report

Abstract

Background

Case presentation

Conclusions

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Abstract

Background

Case presentation

Conclusions

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