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Published in: Obesity Surgery 3/2021

01-03-2021 | Bariatric Surgery | Original Contributions

Long-Term Outcome of Proximal Versus Very-Very Long Limb Roux-en-Y Gastric Bypass: the Roux-Limb to Common Channel Ratio Determines the Long-Term Weight Loss

Authors: Julian Süsstrunk, Ioannis I. Lazaridis, Thomas Köstler, Marko Kraljević, Tarik Delko, Urs Zingg

Published in: Obesity Surgery | Issue 3/2021

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Abstract

Background

The influence of the Roux limb (RL) length on weight loss in Roux-en-Y (RYGB)-type gastric bypass procedures is still unclear. This study analyzes the true impact of RL length by comparing the long-term outcomes of proximal RYGB (PRYGB) and very-very long limb RYGB (VVLL-RYGB).

Methods

RL length in PRYGB was 150 cm. In VVLL-RYGB, common channel length was 100 cm. In both groups, biliopancreatic limbs measured 50–60 cm, resulting in equal total alimentary limb lengths. To adjust for pre-operative differences between groups, and to predict the long-term outcome, a mixed model analysis was performed.

Results

Two hundred thirty-two patients with VVLL-RYGB (73.7% female, mean age 41.1 ± 10 years, initial BMI 45.8 ± 6.3 kg/m2) and 223 with PRYGB (83.9% female, mean age 38.5 ± 11 years, initial BMI 42.9 ± 4.9 kg/m2) were included. Mean follow-up was 9.4 ± 4 years in VVLL-RYGB and 5.3 ± 1.9 years in PRYGB. After 5 years, mean BMI reduction was 15.7 ± 5.9 kg/m2 in VVLL-RYGB and 11.9 ± 4.1 kg/m2 in PRYGB (p < 0.001), and mean %EWL was 78.3 ± 23.1% and 70.2 ± 23.7% (p = 0.002) with a follow-up rate of 78% and 75.9%, respectively. The mixed model analysis showed a significantly higher weight rebound after PRYGB.
Frequency of revisional surgery (i.e., limb length alteration, pouch banding) was similar between VVLL-RYGB and PRYGB (25 vs. 29 revisions, p = 0.463).

Conclusion

The VVLL-RYGB has a significantly higher long-term BMI reduction and a significantly lower weight rebound. The length of the Roux limb significantly influences long-term outcome.
Literature
1.
go back to reference Welbourn R, Hollyman M, Kinsman R, et al. Bariatric surgery worldwide : baseline demographic description and one-year outcomes from the fourth IFSO global registry report. Obes Surg. 2018;2019:782–95. Welbourn R, Hollyman M, Kinsman R, et al. Bariatric surgery worldwide : baseline demographic description and one-year outcomes from the fourth IFSO global registry report. Obes Surg. 2018;2019:782–95.
2.
go back to reference Obeid NR, Malick W, Concors SJ, et al. Long-term outcomes after Roux-en-Y gastric bypass : 10- to 13-year data. Surg Obes Relat Dis. Elsevier. 2016;12:11–22.CrossRef Obeid NR, Malick W, Concors SJ, et al. Long-term outcomes after Roux-en-Y gastric bypass : 10- to 13-year data. Surg Obes Relat Dis. Elsevier. 2016;12:11–22.CrossRef
3.
go back to reference Edholm D, Svensson F, Näslund I, et al. Long-term results 11 years after primary gastric bypass in 384 patients. Surg Obes Relat Dis. 2013;9(5):708–13.CrossRef Edholm D, Svensson F, Näslund I, et al. Long-term results 11 years after primary gastric bypass in 384 patients. Surg Obes Relat Dis. 2013;9(5):708–13.CrossRef
4.
go back to reference Higa K, Ho T, Tercero F, et al. Laparoscopic Roux-en-Y gastric bypass: 10-year follow-up. Surg Obes Relat Dis. 2011;7(4):516–25.CrossRef Higa K, Ho T, Tercero F, et al. Laparoscopic Roux-en-Y gastric bypass: 10-year follow-up. Surg Obes Relat Dis. 2011;7(4):516–25.CrossRef
5.
go back to reference Christou NV, Look D, Maclean LD. Weight gain after short- and long-limb gastric bypass in patients followed for longer than 10 years. Ann Surg. 2006;244(5):734–40.CrossRef Christou NV, Look D, Maclean LD. Weight gain after short- and long-limb gastric bypass in patients followed for longer than 10 years. Ann Surg. 2006;244(5):734–40.CrossRef
6.
go back to reference Shantavasinkul PC, Omotosho P, Corsino L, et al. Predictors of weight regain in patients who underwent Roux-en-Y gastric bypass surgery. Surg Obes Relat Dis. 2016;12(9):1640–5.CrossRef Shantavasinkul PC, Omotosho P, Corsino L, et al. Predictors of weight regain in patients who underwent Roux-en-Y gastric bypass surgery. Surg Obes Relat Dis. 2016;12(9):1640–5.CrossRef
7.
go back to reference Shah K, Nergård BJ, Fagerland MW, et al. Limb length in gastric bypass in super-obese patients—importance of length of total alimentary small bowel tract. Obes Surg. 2019;2019:2012–21.CrossRef Shah K, Nergård BJ, Fagerland MW, et al. Limb length in gastric bypass in super-obese patients—importance of length of total alimentary small bowel tract. Obes Surg. 2019;2019:2012–21.CrossRef
8.
go back to reference Homan J, Boerboom A, Aarts E, et al. A longer biliopancreatic limb in Roux-en-Y gastric bypass improves weight loss in the first years after surgery : results of a randomized controlled trial. Obes Surg. 2018;28:3744–55.CrossRef Homan J, Boerboom A, Aarts E, et al. A longer biliopancreatic limb in Roux-en-Y gastric bypass improves weight loss in the first years after surgery : results of a randomized controlled trial. Obes Surg. 2018;28:3744–55.CrossRef
9.
go back to reference Buchwald H, Avidor Y, Braunwald E, et al. Bariatric surgery - a systematic review and meta-analysis. JAMA Surg. 2004;292(14):1724–38.CrossRef Buchwald H, Avidor Y, Braunwald E, et al. Bariatric surgery - a systematic review and meta-analysis. JAMA Surg. 2004;292(14):1724–38.CrossRef
10.
go back to reference Kellum JM, Chikunguwo SM, Maher JW, et al. Long-term results of malabsorptive distal Roux-en-Y gastric bypass in superobese patients. Surg Obes Relat Dis. 2011;7(2):189–93.CrossRef Kellum JM, Chikunguwo SM, Maher JW, et al. Long-term results of malabsorptive distal Roux-en-Y gastric bypass in superobese patients. Surg Obes Relat Dis. 2011;7(2):189–93.CrossRef
11.
go back to reference Kraljević M, Köstler T, Süsstrunk J, et al. Revisional surgery for insufficient loss or regain of weight after Roux-en-Y gastric bypass: biliopancreatic limb length matters. Obes Surg. 2020;30(3):804–11.CrossRef Kraljević M, Köstler T, Süsstrunk J, et al. Revisional surgery for insufficient loss or regain of weight after Roux-en-Y gastric bypass: biliopancreatic limb length matters. Obes Surg. 2020;30(3):804–11.CrossRef
12.
go back to reference Madan AK, Harper JL, Tichansky DS. Techniques of laparoscopic gastric bypass: on-line survey of American Society for Bariatric Surgery practicing surgeons. Surg Obes Relat Dis. 2008;4(2):166–72.CrossRef Madan AK, Harper JL, Tichansky DS. Techniques of laparoscopic gastric bypass: on-line survey of American Society for Bariatric Surgery practicing surgeons. Surg Obes Relat Dis. 2008;4(2):166–72.CrossRef
13.
go back to reference Bhandari M, Fobi MAL, Buchwald JN, et al. Standardization of bariatric metabolic procedures: world consensus meeting statement. Obes Surg. 2019;29:309–45.CrossRef Bhandari M, Fobi MAL, Buchwald JN, et al. Standardization of bariatric metabolic procedures: world consensus meeting statement. Obes Surg. 2019;29:309–45.CrossRef
14.
go back to reference Brolin RE, Kenler HA, Gorman JH, et al. Long-limb gastric bypass in the superobese: a prospective randomized study. Ann Surg. 1992;215(4):387–95.CrossRef Brolin RE, Kenler HA, Gorman JH, et al. Long-limb gastric bypass in the superobese: a prospective randomized study. Ann Surg. 1992;215(4):387–95.CrossRef
15.
go back to reference Brolin RE, LaMarca LB, Kenler HA, et al. Malabsorptive gastric bypass in patients with superobesity. J Gastrointest Surg. 2002;6(2):195–205.CrossRef Brolin RE, LaMarca LB, Kenler HA, et al. Malabsorptive gastric bypass in patients with superobesity. J Gastrointest Surg. 2002;6(2):195–205.CrossRef
16.
go back to reference Nelson WK, Fatima J, Houghton SG, et al. The malabsorptive very, very long limb Roux-en-Y gastric bypass for super obesity: results in 257 patients. Surgery. 2006;140(4):517–23.CrossRef Nelson WK, Fatima J, Houghton SG, et al. The malabsorptive very, very long limb Roux-en-Y gastric bypass for super obesity: results in 257 patients. Surgery. 2006;140(4):517–23.CrossRef
17.
go back to reference Thurnheer M, Bisang P, Ernst B, et al. A novel distal very long Roux-en Y gastric bypass (DVLRYGB) as a primary bariatric procedure—complication rates, weight loss, and nutritional/metabolic changes in the first 355 patients. Obes Surg. 2012;22(9):1427–36.CrossRef Thurnheer M, Bisang P, Ernst B, et al. A novel distal very long Roux-en Y gastric bypass (DVLRYGB) as a primary bariatric procedure—complication rates, weight loss, and nutritional/metabolic changes in the first 355 patients. Obes Surg. 2012;22(9):1427–36.CrossRef
18.
go back to reference Gan J, Wang Y, Zhou X. Whether a short or long alimentary limb influences weight loss in gastric bypass: a systematic review and meta-analysis. Obes Surg. 2018;28(11):3701–10.CrossRef Gan J, Wang Y, Zhou X. Whether a short or long alimentary limb influences weight loss in gastric bypass: a systematic review and meta-analysis. Obes Surg. 2018;28(11):3701–10.CrossRef
19.
go back to reference Ahmed B, King WC, Gourash W, et al. Proximal Roux-en-Y gastric bypass : addressing the myth of limb length. Surgery. 2019;166:445–55.CrossRef Ahmed B, King WC, Gourash W, et al. Proximal Roux-en-Y gastric bypass : addressing the myth of limb length. Surgery. 2019;166:445–55.CrossRef
20.
go back to reference Savassi-Rocha AL, Diniz MTC, Savassi-Rocha PR, et al. Rodrigues De Almeida Sanches S, Diniz MDFHS, et al. Influence of jejunoileal and common limb length on weight loss following Roux-en-Y gastric bypass. Obes Surg. 2008;18(11):1364–8.CrossRef Savassi-Rocha AL, Diniz MTC, Savassi-Rocha PR, et al. Rodrigues De Almeida Sanches S, Diniz MDFHS, et al. Influence of jejunoileal and common limb length on weight loss following Roux-en-Y gastric bypass. Obes Surg. 2008;18(11):1364–8.CrossRef
21.
go back to reference Reinhold R. Critical analysis of long term weight loss following gastric bypass. Surg Gynecol Obstet. 1982;3(155):385–94. Reinhold R. Critical analysis of long term weight loss following gastric bypass. Surg Gynecol Obstet. 1982;3(155):385–94.
22.
go back to reference Mehaffey JH, Lapar DJ, Clement KC, et al. 10-year outcomes after Roux-en-Y gastric bypass. Ann Surg. 2016;264(1):121–6.CrossRef Mehaffey JH, Lapar DJ, Clement KC, et al. 10-year outcomes after Roux-en-Y gastric bypass. Ann Surg. 2016;264(1):121–6.CrossRef
23.
go back to reference O’Brien PE, Hindle A, Brennan L, et al. Long-term outcomes after bariatric surgery: a systematic review and meta-analysis of weight loss at 10 or more years for all bariatric procedures and a single-centre review of 20-year outcomes after adjustable gastric banding. Obes Surg. 2019;29(1):3–14.CrossRef O’Brien PE, Hindle A, Brennan L, et al. Long-term outcomes after bariatric surgery: a systematic review and meta-analysis of weight loss at 10 or more years for all bariatric procedures and a single-centre review of 20-year outcomes after adjustable gastric banding. Obes Surg. 2019;29(1):3–14.CrossRef
24.
go back to reference Yang P, Chen B, Xiang S, et al. Long-term outcomes of laparoscopic sleeve gastrectomy versus Roux-en-Y gastric bypass for morbid obesity: results from a meta-analysis of randomized controlled trials. Surg Obes Relat Dis. 2019;15(4):546–55. Yang P, Chen B, Xiang S, et al. Long-term outcomes of laparoscopic sleeve gastrectomy versus Roux-en-Y gastric bypass for morbid obesity: results from a meta-analysis of randomized controlled trials. Surg Obes Relat Dis. 2019;15(4):546–55.
25.
go back to reference Toolabi K, Sarkardeh M, Vasigh M, et al. Comparison of laparoscopic Roux-en-Y gastric bypass and laparoscopic sleeve gastrectomy on weight loss, weight regain, and remission of comorbidities: a 5 years of follow-up study. Obes Surg. 2020;30(2):440–5.CrossRef Toolabi K, Sarkardeh M, Vasigh M, et al. Comparison of laparoscopic Roux-en-Y gastric bypass and laparoscopic sleeve gastrectomy on weight loss, weight regain, and remission of comorbidities: a 5 years of follow-up study. Obes Surg. 2020;30(2):440–5.CrossRef
26.
go back to reference Thomas DD, Anderson WA, Apovian CM, et al. Weight recidivism after Roux-en-Y gastric bypass surgery: an 11-year experience in a multiethnic medical center. Obesity. 2019;27(2):217–25.CrossRef Thomas DD, Anderson WA, Apovian CM, et al. Weight recidivism after Roux-en-Y gastric bypass surgery: an 11-year experience in a multiethnic medical center. Obesity. 2019;27(2):217–25.CrossRef
27.
go back to reference Maciejewski ML, Arterburn DE, Van Scoyoc L, et al. Bariatric surgery and long-term durability of weight loss. JAMA Surg. 2017;151(11):1046–55.CrossRef Maciejewski ML, Arterburn DE, Van Scoyoc L, et al. Bariatric surgery and long-term durability of weight loss. JAMA Surg. 2017;151(11):1046–55.CrossRef
28.
go back to reference Torres JC, Why I. Prefer gastric bypass distal Roux-en-Y gastroileostomy. Obes Surg. 1991;1:189–94.CrossRef Torres JC, Why I. Prefer gastric bypass distal Roux-en-Y gastroileostomy. Obes Surg. 1991;1:189–94.CrossRef
29.
go back to reference Ghiassi S, Higa K, Chang S, et al. Conversion of standard Roux-en-Y gastric bypass to distal bypass for weight loss failure and metabolic syndrome : 3-year follow-up and evolution of technique to reduce nutritional complications. Surg Obes Relat Dis. 2018;14(5):554–61.CrossRef Ghiassi S, Higa K, Chang S, et al. Conversion of standard Roux-en-Y gastric bypass to distal bypass for weight loss failure and metabolic syndrome : 3-year follow-up and evolution of technique to reduce nutritional complications. Surg Obes Relat Dis. 2018;14(5):554–61.CrossRef
30.
go back to reference Nergaard BJ, Leifsson BG, Hedenbro J, et al. Gastric bypass with long alimentary limb or long pancreato-biliary limb—long-term results on weight loss, resolution of co-morbidities and metabolic parameters. Obes Surg. 2014;24(10):1595–602.CrossRef Nergaard BJ, Leifsson BG, Hedenbro J, et al. Gastric bypass with long alimentary limb or long pancreato-biliary limb—long-term results on weight loss, resolution of co-morbidities and metabolic parameters. Obes Surg. 2014;24(10):1595–602.CrossRef
31.
go back to reference Leeman M, Gadiot RPM, Wijnand JMA, et al. Effects of standard v. very long roux limb Roux-en-Y gastric bypass on nutrient status: a 1-year follow-up report from the Dutch Common Channel trial (DUCATI) study. Br J Nutr. 2020;123(12):1434–40.CrossRef Leeman M, Gadiot RPM, Wijnand JMA, et al. Effects of standard v. very long roux limb Roux-en-Y gastric bypass on nutrient status: a 1-year follow-up report from the Dutch Common Channel trial (DUCATI) study. Br J Nutr. 2020;123(12):1434–40.CrossRef
32.
go back to reference Rawlins ML, Teel D, Hedgcorth K, et al. Revision of Roux-en- Y gastric bypass to distal bypass for failed weight loss. Surg Obes Relat Dis. Elsevier Inc. 2011;7(1):45–9.CrossRef Rawlins ML, Teel D, Hedgcorth K, et al. Revision of Roux-en- Y gastric bypass to distal bypass for failed weight loss. Surg Obes Relat Dis. Elsevier Inc. 2011;7(1):45–9.CrossRef
33.
go back to reference van der Burgh Y, Boerboom A, de Boer H, et al. Weight loss and malnutrition after conversion of the primary Roux-en-Y gastric bypass to distal gastric bypass in patients with morbid obesity. Surg Obes Relat Dis. Elsevier Inc. 2020;16(3):381–8.CrossRef van der Burgh Y, Boerboom A, de Boer H, et al. Weight loss and malnutrition after conversion of the primary Roux-en-Y gastric bypass to distal gastric bypass in patients with morbid obesity. Surg Obes Relat Dis. Elsevier Inc. 2020;16(3):381–8.CrossRef
34.
go back to reference Pinheiro JS, Schiavon CA, Pereira PB, et al. Long-long limb Roux-en-Y gastric bypass is more efficacious in treatment of type 2 diabetes and lipid disorders in super-obese patients. Surg Obes Relat Dis. 2008;4(4):521–5.CrossRef Pinheiro JS, Schiavon CA, Pereira PB, et al. Long-long limb Roux-en-Y gastric bypass is more efficacious in treatment of type 2 diabetes and lipid disorders in super-obese patients. Surg Obes Relat Dis. 2008;4(4):521–5.CrossRef
Metadata
Title
Long-Term Outcome of Proximal Versus Very-Very Long Limb Roux-en-Y Gastric Bypass: the Roux-Limb to Common Channel Ratio Determines the Long-Term Weight Loss
Authors
Julian Süsstrunk
Ioannis I. Lazaridis
Thomas Köstler
Marko Kraljević
Tarik Delko
Urs Zingg
Publication date
01-03-2021
Publisher
Springer US
Published in
Obesity Surgery / Issue 3/2021
Print ISSN: 0960-8923
Electronic ISSN: 1708-0428
DOI
https://doi.org/10.1007/s11695-020-05109-8

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