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European Journal of Medical Research
Published in: European Journal of Medical Research 1/2019

Open Access 01-12-2019 | Back Pain | Research

Distribution of Modic changes in patients with low back pain and its related factors

Authors: Yufeng Chen, Jie Bao, Qi Yan, Cenhao Wu, Huilin Yang, Jun Zou

Published in: European Journal of Medical Research | Issue 1/2019

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Abstract

Background

To summarize the clinical distribution of Modic changes in patients with low back pain and explore the related factors.

Methods

A total of 153 patients were enrolled. Gender, age, disk degeneration, herniation, involved segments, lumbar lordosis angle, and endplate concave angle were recorded, respectively. Patients were divided into two or more groups according to a different classification. The relevant factors were studied with a multivariate logistic regression analysis to analyze their correlation.

Results

A total of 35 patients with type I changes, 110 patients with type II changes, and 8 patients with type III changes. In total, 204 disks were found with Modic changes, L1/2 (10 disks), L2/3 (18 disks), L3/4 (17 disks), L4/5 (76 disks), and L5/S1 (81 disks). Type I changes were distributed mainly under the age of 50. Multivariate regression showed that gender, age, disk degeneration, lumbar lordosis, L4/5 segment lordosis angle, and L5 lower endplate concave angle were related with different types of Modic changes. The regression equation Y = 2.410 − 1.361S − 0.633A − 0.654P + 1.106L − 0.990D (Y means type I changes, S means gender, A means age, P means disk degeneration, L means L4/5 segment lordosis angle, and D means L5 upper endplate concave angle). The OR values were S = 0.256, A = 0.531, P = 0.520, L = 3.022, D = 0.372, respectively.

Conclusions

Type II changes are the most common, followed by type I. Modic changes mostly occur in L4/5 and L5/S1; young, male, lower-grade disk degeneration, normal physiological curvature of the lumbar spine, and normal endplate concave angle were associated with type I changes; gender and lumbar curvature were the most relevant factors for different types.
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Metadata
Title
Distribution of Modic changes in patients with low back pain and its related factors
Authors
Yufeng Chen
Jie Bao
Qi Yan
Cenhao Wu
Huilin Yang
Jun Zou
Publication date
01-12-2019
Publisher
BioMed Central
Published in
European Journal of Medical Research / Issue 1/2019
Electronic ISSN: 2047-783X
DOI
https://doi.org/10.1186/s40001-019-0393-6

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