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Published in: Journal of Medical Case Reports 1/2008

Open Access 01-12-2008 | Case report

Avascular necrosis of humeral head in an elderly patient with tuberculosis: a case report

Authors: Renu Agarwal, Ruchika Gupta, Sompal Singh, Kusum Gupta, Madhur Kudesia

Published in: Journal of Medical Case Reports | Issue 1/2008

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Abstract

Introduction

Osteonecrosis (avascular necrosis) is known to be caused by high-dose corticosteroid therapy, alcoholism and rarely by infections. However, a tubercular etiology of this condition is very rare. A review of the literature yielded only a few cases of polyarticular tuberculosis with osteonecrosis in immunosuppressed individuals. No case of monoarticular tubercular osteonecrosis diagnosed by aspiration cytology was found. Since tuberculosis is a curable disease, an early and accurate diagnosis is essential.

Case presentation

A 60-year-old Indian man presented with diffuse swelling and pain in the left shoulder for the previous 6 months. A computed tomography scan of the left shoulder revealed crescentic lucency in the humeral head, suggestive of osteonecrosis. Fine needle aspiration cytology smears from the swelling showed features of an acute suppurative lesion. Stain for acid-fast bacillus was positive and thus, a final clinico-pathological diagnosis of osteonecrosis of humeral head with tubercular etiology was rendered. The patient was initiated on anti-tuberculous therapy with symptomatic improvement in his condition.

Conclusion

Osteonecrosis, a debilitating disease, may rarely occur due to tuberculosis, especially in endemic areas. Fine needle aspiration cytology is an effective and inexpensive modality for an early diagnosis of the tubercular etiology of osteonecrosis.
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Literature
1.
go back to reference Assouline-Dayan Y, Chang C, Greenspan A, Shoenfeld Y, Gershwin ME: Pathogenesis and natural history of osteonecrosis. Semin Arthritis Rheum. 2002, 32: 94-124.CrossRefPubMed Assouline-Dayan Y, Chang C, Greenspan A, Shoenfeld Y, Gershwin ME: Pathogenesis and natural history of osteonecrosis. Semin Arthritis Rheum. 2002, 32: 94-124.CrossRefPubMed
2.
go back to reference Qaqish RB, Sims KA: Bone disorders associated with the human immunodeficiency virus: pathogenesis and management. Pharmacotherapy. 2004, 24: 1331-1346. 10.1592/phco.24.14.1331.43150.CrossRefPubMed Qaqish RB, Sims KA: Bone disorders associated with the human immunodeficiency virus: pathogenesis and management. Pharmacotherapy. 2004, 24: 1331-1346. 10.1592/phco.24.14.1331.43150.CrossRefPubMed
3.
go back to reference Campbell WN, Joshi M, Sileo D: Osteonecrosis following meningococcemia and disseminated intravascular coagulation in an adult: case report and review. Clin Infect Dis. 1997, 24: 452-455.CrossRefPubMed Campbell WN, Joshi M, Sileo D: Osteonecrosis following meningococcemia and disseminated intravascular coagulation in an adult: case report and review. Clin Infect Dis. 1997, 24: 452-455.CrossRefPubMed
4.
go back to reference Cheung NT, Saklatvala J, Dawes PT: Multiple joint avascular necrosis: beware of tuberculosis and human immunodeficiency virus – a rare but important cause. Br J Rheumatol. 1995, 34: 387-391. 10.1093/rheumatology/34.4.387.CrossRefPubMed Cheung NT, Saklatvala J, Dawes PT: Multiple joint avascular necrosis: beware of tuberculosis and human immunodeficiency virus – a rare but important cause. Br J Rheumatol. 1995, 34: 387-391. 10.1093/rheumatology/34.4.387.CrossRefPubMed
5.
go back to reference Kemp HBS, Lloyd-Roberts GC: Avascular necrosis of the capital epiphysis following osteomyelitis of the proximal femoral metaphysis. J Bone Joint Surg Br. 1974, 56: 688-697.PubMed Kemp HBS, Lloyd-Roberts GC: Avascular necrosis of the capital epiphysis following osteomyelitis of the proximal femoral metaphysis. J Bone Joint Surg Br. 1974, 56: 688-697.PubMed
6.
go back to reference Raviglione MC, Snider DE, Kochi A: Global epidemiology of tuberculosis: morbidity and mortality of a worldwide epidemic. JAMA. 1995, 273: 220-226. 10.1001/jama.273.3.220.CrossRefPubMed Raviglione MC, Snider DE, Kochi A: Global epidemiology of tuberculosis: morbidity and mortality of a worldwide epidemic. JAMA. 1995, 273: 220-226. 10.1001/jama.273.3.220.CrossRefPubMed
7.
go back to reference Kumar R: Spinal tuberculosis: with reference to the children of northern India. Child's Nerv Syst. 2005, 21: 19-26. 10.1007/s00381-004-1029-9.CrossRef Kumar R: Spinal tuberculosis: with reference to the children of northern India. Child's Nerv Syst. 2005, 21: 19-26. 10.1007/s00381-004-1029-9.CrossRef
Metadata
Title
Avascular necrosis of humeral head in an elderly patient with tuberculosis: a case report
Authors
Renu Agarwal
Ruchika Gupta
Sompal Singh
Kusum Gupta
Madhur Kudesia
Publication date
01-12-2008
Publisher
BioMed Central
Published in
Journal of Medical Case Reports / Issue 1/2008
Electronic ISSN: 1752-1947
DOI
https://doi.org/10.1186/1752-1947-2-361

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