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Open Access 01-12-2015 | Review

Avascular necrosis in pediatric systemic lupus erythematosus: a brief report and review of the literature

Authors: Reut Gurion, Vin Tangpricha, Eric Yow, Laura E Schanberg, Grace A McComsey, Angela Byun Robinson, for the Atherosclerosis Prevention in Pediatric Lupus Erythematosus Investigators

Published in: Pediatric Rheumatology | Issue 1/2015

Abstract

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Avascular necrosis (AVN) occurs in several chronic illnesses, including systemic lupus erythematosus (SLE), but can also occur in healthy children. There are multiple theories to explain why and how AVN occurs, but an exact mechanism has yet to be unraveled. AVN in the pediatric lupus population is understudied. The Atherosclerosis Prevention in Pediatric Lupus Erythematosus (APPLE) trial, provides an excellent venue to conduct an exploratory analysis to assess associations between AVN and demographics, SLE disease activity and vitamin D deficiency. Herein we present a brief report describing our findings, as well as reviewing the literature on AVN in SLE and other entities.

Trial registration

ClinicalTrials.gov identifier: NCT00065806.

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Title: Avascular necrosis in pediatric systemic lupus erythematosus: a brief report and review of the literature
Authors: Reut Gurion
Vin Tangpricha
Eric Yow
Laura E Schanberg
Grace A McComsey
Angela Byun Robinson
for the Atherosclerosis Prevention in Pediatric Lupus Erythematosus Investigators
Publication date: 01-12-2015
Publisher: BioMed Central
Published in: Pediatric Rheumatology / Issue 1/2015
Electronic ISSN: 1546-0096
DOI: https://doi.org/10.1186/s12969-015-0008-x

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Avascular necrosis in pediatric systemic lupus erythematosus: a brief report and review of the literature

Abstract

ᅟ

Trial registration

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Abstract

ᅟ

Trial registration

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