Skip to main content
Top
Published in: International Ophthalmology 6/2011

01-12-2011 | Case Report

Autofluorescence and optical coherence tomography findings in optic disc pit-associated maculopathy: case series

Authors: Mehmet Y. Teke, Ufuk Elgin, Pinar Ozdal, Faruk Ozturk

Published in: International Ophthalmology | Issue 6/2011

Login to get access

Abstract

The aim of this case series was to report and discuss the clinical, fundus autofluorescence (FAF), and optical coherence tomography (OCT) findings of four eyes of three cases with optic disc pit (ODP)-related serous macular detachment. Three cases were referred to the retina department of our hospital for decreased visual acuities in four of their eyes. In addition to ophthalmological examinations, OCT and FAF were also performed. ODP-related serous macular detachment was detected clinically in all the eyes. OCT also showed two typical components named as ‘bilaminar structure’ in all eyes and OCT and FAF photography showed precipitates in the retinal outer layers of the detachment area in three eyes. OCT and autofluorescence photography findings can support clinical observations in the diagnosis of ODP-related maculopathy.
Literature
1.
go back to reference Brown GC, Shields JA, Goldberg RE (1980) Congenital pits of the optic nerve head. II. Clinical studies in human. Ophthalmology 87:51–65PubMed Brown GC, Shields JA, Goldberg RE (1980) Congenital pits of the optic nerve head. II. Clinical studies in human. Ophthalmology 87:51–65PubMed
2.
go back to reference Sadun AA (2001) Optic disc pits and associated serous macular detachment. In: Ryan SJ, Schachat AP (eds) Retina 2nd, vol 2. Mosby, St Louis, pp 1821–1827 Sadun AA (2001) Optic disc pits and associated serous macular detachment. In: Ryan SJ, Schachat AP (eds) Retina 2nd, vol 2. Mosby, St Louis, pp 1821–1827
3.
go back to reference Sugar HS (1962) Congenital pits in the optic disc with acquired macular pathology. Am J Ophthalmol 53:307–311PubMed Sugar HS (1962) Congenital pits in the optic disc with acquired macular pathology. Am J Ophthalmol 53:307–311PubMed
4.
go back to reference Bonnet M (1991) Serous macular detachment associated with optic nerve pits. Graefes Arch Clin Exp Ophthalmol 229:526–532PubMedCrossRef Bonnet M (1991) Serous macular detachment associated with optic nerve pits. Graefes Arch Clin Exp Ophthalmol 229:526–532PubMedCrossRef
5.
go back to reference Feeney-Burns L, Berman ER, Rothman H (1980) Lipofuscin of human retinal pigment epithelium. Am J Ophthalmol 90:783–791PubMed Feeney-Burns L, Berman ER, Rothman H (1980) Lipofuscin of human retinal pigment epithelium. Am J Ophthalmol 90:783–791PubMed
6.
go back to reference Delori FC, Goger DG, Dorey CK (2001) Age-related accumulation and spatial distribution of lipofuscin in RPE of normal subjects. Invest Ophthalmol Vis Sci 42:1856–1866 Delori FC, Goger DG, Dorey CK (2001) Age-related accumulation and spatial distribution of lipofuscin in RPE of normal subjects. Invest Ophthalmol Vis Sci 42:1856–1866
7.
go back to reference Spaide RF (2008) Autofluorescence from the outer retina and subretinal space: hypothesis and review. Retina 28:5–35PubMedCrossRef Spaide RF (2008) Autofluorescence from the outer retina and subretinal space: hypothesis and review. Retina 28:5–35PubMedCrossRef
8.
go back to reference Choudhry N, Giani A, Miller JW (2010) Fundus autofluorescence in geographic atrophy: a review. Semin Ophthalmol 25:206–213PubMedCrossRef Choudhry N, Giani A, Miller JW (2010) Fundus autofluorescence in geographic atrophy: a review. Semin Ophthalmol 25:206–213PubMedCrossRef
9.
go back to reference Liu J, Itagaki Y, Ben-Shabat S, Nakanishi K, Sparrow JR (2000) The biosynthesis of A2E, a fluorophore of aging retina, involves the formation of the precursor, A2-PE, in the photoreceptor outer segment membrane. J Biol Chem 275:29354–29360PubMedCrossRef Liu J, Itagaki Y, Ben-Shabat S, Nakanishi K, Sparrow JR (2000) The biosynthesis of A2E, a fluorophore of aging retina, involves the formation of the precursor, A2-PE, in the photoreceptor outer segment membrane. J Biol Chem 275:29354–29360PubMedCrossRef
10.
go back to reference Karacorlu SA, Karacorlu M, Ozdemir H, Burumcek E, Esgin H (2007) Optical coherence tomography in optic pit maculopathy. Int Ophthalmol 27:293–297PubMedCrossRef Karacorlu SA, Karacorlu M, Ozdemir H, Burumcek E, Esgin H (2007) Optical coherence tomography in optic pit maculopathy. Int Ophthalmol 27:293–297PubMedCrossRef
11.
go back to reference Doyle E, Trivedi D, Good P, Scott RA, Kirkby GR (2009) High-resolution optical coherence tomography demonstration of membranes spanning optic disc pits and colobomas. Br J Ophthalmol 93:360–365PubMedCrossRef Doyle E, Trivedi D, Good P, Scott RA, Kirkby GR (2009) High-resolution optical coherence tomography demonstration of membranes spanning optic disc pits and colobomas. Br J Ophthalmol 93:360–365PubMedCrossRef
12.
go back to reference Trieschmann M, Spital G, Lommatzsch A, van Kuijk E, Fitzke F, Bird AC, Pauleikhoff D (2003) Macular pigment: quantitative analysis on autofluorescence images. Graefes Arch Clin Exp Ophthalmol 241:1006–1012PubMedCrossRef Trieschmann M, Spital G, Lommatzsch A, van Kuijk E, Fitzke F, Bird AC, Pauleikhoff D (2003) Macular pigment: quantitative analysis on autofluorescence images. Graefes Arch Clin Exp Ophthalmol 241:1006–1012PubMedCrossRef
13.
go back to reference Laud K, Visaetsilpanonta S, Yannuzzi LA, Spaide RF (2007) Autofluorescence imaging of optic pit maculopathy. Retina 27:116–119PubMedCrossRef Laud K, Visaetsilpanonta S, Yannuzzi LA, Spaide RF (2007) Autofluorescence imaging of optic pit maculopathy. Retina 27:116–119PubMedCrossRef
14.
go back to reference Hiraoka T, Inoue M, Ninomiya Y, Hirakata A (2010) Infrared and fundus autofluorescence imaging in eyes with optic disc pit maculopathy. Clin Experiment Ophthalmol 38:669–677PubMedCrossRef Hiraoka T, Inoue M, Ninomiya Y, Hirakata A (2010) Infrared and fundus autofluorescence imaging in eyes with optic disc pit maculopathy. Clin Experiment Ophthalmol 38:669–677PubMedCrossRef
Metadata
Title
Autofluorescence and optical coherence tomography findings in optic disc pit-associated maculopathy: case series
Authors
Mehmet Y. Teke
Ufuk Elgin
Pinar Ozdal
Faruk Ozturk
Publication date
01-12-2011
Publisher
Springer Netherlands
Published in
International Ophthalmology / Issue 6/2011
Print ISSN: 0165-5701
Electronic ISSN: 1573-2630
DOI
https://doi.org/10.1007/s10792-011-9484-2

Other articles of this Issue 6/2011

International Ophthalmology 6/2011 Go to the issue