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European Archives of Oto-Rhino-Laryngology
Published in: European Archives of Oto-Rhino-Laryngology 10/2019

01-10-2019 | Audiometry | Otology

Evaluation of hearing loss and tinnitus in Behcet’s disease

Authors: Ahmet Karadağ, Mujde Karadağ, Adem Bora, Emrullah Hayta, A. Bahadır Çetin, Sevil C. Doğan, Kasım Durmuş, E. Elif Altuntaş

Published in: European Archives of Oto-Rhino-Laryngology | Issue 10/2019

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Abstract

Objective

The aim of this study is to evaluate sensorineuralhearing loss (SHNL) and tinnitus in patients with Behcet’s disease (BD), while also determining the association between the clinical symptoms of BD and the disease duration with the development of hearing loss.

Materials and methods

The study included 44 patients with BD and 42 healthy volunteers as the control group. The level of tinnitus-induced annoyance and the effects of tinnitus on daily life were evaluated with Visual Analog Scale (VAS) and the Tinnitus Reaction Questionnaire (TRQ). The hearing levels of all participants were measured with high-frequency audiometry and transient auto-acoustic emission tests.

Results

The patients with BD were significantly more affected by SNHL and tinnitus than the controls (p < 0.05). The correlation between disease duration and age among those with SNHL was statistically significant (p < 0.05). No association was found between the clinical findings and SNHL and tinnitus (p > 0.05) in the BD patients.

Conclusion

In the present study, high-frequency SNHL was found to be common in among the patients with BD. SNHL in BD is positively correlated with the patients’ age of the and the disease duration.
Literature
1.
Alpsoy E (2005) Behçet’s disease: treatment of mucocutaneous lesions. Clin Exp Rheumatol 23:532–539PubMed
2.
Greco A, De Virgilio A, Ralli M, Ciofalo A et al (2018) Behçet’s disease: New insights into pathophysiology, clinical features and treatment options. Autoimmun Rev 17(6):567–575CrossRef
3.
Seyahi E (2016) Behçet's disease: How to diagnose and treat vascular involvement. Best Pract Res Clin Rheumatol 30(2):279–295CrossRef
4.
Ghate JV, Jorizzo JL (1999) Behcet’s disease and complex aphthosis. J Am Acad Dermatol 40:1–18CrossRef
5.
Watad A, Tiosano S, Yahav D et al (2016) Behçet’s disease ‬and FMF: two sides of the same coin or just an association? A cross-sectional study. Eur J Intern Med 39:75–78CrossRef
6.
Yazıcı H, Tuzun Y, Pazarlı H, Yurdakul S et al (1984) Influence of age of onset and patient's sex on the prevalence and severity of manifestations of Behçet’s syndrome. Ann Rheum Dis 43:783–789CrossRef
7.
Mancini P, Atturo F, Di Mario A et al (2018) Hearing loss in autoimmune disorders: Prevalence and therapeutic options. Autoimmun Rev 17(7):644–652CrossRef
8.
Ahmadzadeh A, Daraei M, Jalessi M et al (2017) Author information Hearing status in patients with rheumatoid arthritis. J Laryngol Otol 131(10):895–989CrossRef
9.
Greco A, Marinelli C, A. Gallo,M, et al (2014) Immunological model and otological manifestations of Behçet's disease. Open Immunol J 7:1–7CrossRef
10.
Sonbay ND, Saka C, Tatlican S, Vuralkan E, Aygener N, Eren C, Akin I (2014) Audiological evaluation in patients with Behçet's disease. J Laryngol Otol 128(8):694–697CrossRef
11.
Cinar S, Cinar F, Kiran S (2012) Is there a need for audiologic evaluation in patients with Behçet disease? Ear Nose Throat J 91(3):E15–E19CrossRef
12.
Barna BP, Hughes GB (1988) Autoimmunity and otologic disease: clinical and experimental aspects. Clin Lab Med 8:385–398CrossRef
13.
Rossini BAA, Penido NO, Munhoz MSL et al (2017) Sudden Sensorioneural Hearing Loss and Autoimmune Systemic Diseases. Int Arch Otorhinolaryngol 21(3):213–223CrossRef
14.
Sota J, Vitale A, Orlando I et al (2017) Auditory involvement in Behcet's disease: relationship with demographic, clinical, and therapeutic characteristics. Clin Rheumatol 36(2):445–449CrossRef
15.
Morales-Angulo C, Vergara Pastrana S, Obeso-Agüera S, Acle L et al (2014) Otorhinolaryngological manifestations in patients with Behçet disease. Acta Otorrinolaringol Esp 65(1):15–21CrossRef
16.
International Study Group for Behcet's Disease (1990) Criteria for diagnosis of Behcet's disease. Lancet 335:1078–1080
17.
Guidelines for screening for hearing impairment and middle- ear disorders, (1990) Working Group on acoustic immittance measurements and the committee on audiologic evaluation. American Speech-Language-Hearing Association. ASHA Suppl 2:17–24
18.
Wilson PH, Henry J, Bowen M et al (1991) Tinnitus reaction questionnaire: pyscometric properties of a measure of distress associated with tinnitus. J Speech Hear Res 34:197–201CrossRef
19.
Eğilmez OK, Kalcıoğlu MT, Kökten N (2014) Questionnaire methods used in the psychosomatic evaluation of tinnitus. J Ear Nose Throat 24(5):303–310CrossRef
20.
Ak E, Harputluoglu U, Oghan F et al (2004) Behçet’s disease and hearing loss. Auris Nasus Larynx 31:29–33CrossRef
21.
Süslü AE, Polat M, Köybaşi S et al (2010) Inner ear involvement in Behçet's disease. Auris Nasus Larynx 37(3):286–290CrossRef
22.
Choung YH, Cho MJ, Park K et al (2006) Audiovestibular disturbance in patients with Behcet’s disease. Laryngoscope 116:1987–1990CrossRef
23.
Andreoli C, Savastano M (1989) Audiologic pathology in Behçet syndrome. Am J Otol 10:466–467PubMed
24.
Alajouanine T, Castaigne P, Lhermitte F et al (1961) The meningoencephalitis of Behcet’s disease. Presse Med 69:2579–2582PubMed
25.
Bakhshaee M, Ghasemi MM, Hatef MR et al (2007) Hearing loss in Behçet syndrome. Otolaryngol Head Neck Surg 137:439–442CrossRef
26.
Aslan S, Serarslan G, Savas N et al (2010) Hearing loss in patients with Behçet’s disease: an audiological and transient evoked otoacoustic emission study. J Laryngol Otol 124:10–15CrossRef
27.
Bayazit Y, Evereklioglu C, Ozer E et al (2004) Neurotological status in Behcet’s disease and its ophthalmological correlates. Postgrad Med J 80:724–728CrossRef
28.
Yarıktaş M, Yıldırım M, Döner F et al (2004) Hearing loss in Behcet's disease. Medical journal of Suleyman Demirel University 11(1):18–20
29.
Kemal O, Anadolu Y, Boyvat A et al (2013) Behcet disease as a cause of hearing loss: a prospective, placebo-controlled study of 29 patients. Ear Nose Throat 92(3):112–120CrossRef
Metadata
Title
Evaluation of hearing loss and tinnitus in Behcet’s disease
Authors
Ahmet Karadağ
Mujde Karadağ
Adem Bora
Emrullah Hayta
A. Bahadır Çetin
Sevil C. Doğan
Kasım Durmuş
E. Elif Altuntaş
Publication date
01-10-2019
Publisher
Springer Berlin Heidelberg
Published in
European Archives of Oto-Rhino-Laryngology / Issue 10/2019
Print ISSN: 0937-4477
Electronic ISSN: 1434-4726
DOI
https://doi.org/10.1007/s00405-019-05506-5

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