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BMC Ophthalmology

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Open Access 01-12-2012 | Case report

Atypical vitelliform macular dystrophy misdiagnosed as chronic central serous chorioretinopathy: case reports

Authors: Young Seob Lee, Eung-Suk Kim, Moosang Kim, Young-Gyun Kim, Hyung-Woo Kwak, Seung-Young Yu

Published in: BMC Ophthalmology | Issue 1/2012

Abstract

Background

To report two cases of atypical vitelliform macular dystrophy misdiagnosed as chronic central serous chorioretinopathy.

Case presentation

Two patients with incidentally discovered abnormalities of the retina without specific symptoms were referred to our hospital for consultation. Bilateral macula atrophic lesions were observed and optical coherence tomography revealed serous retinal detachment in the macula. Fluorescein angiography showed multiple leakages around the central hypofluorescent area and indocyanine green angiography showed partially dilated choroidal vessels. Fundus autofluorescence (FAF) showed a decreasing pattern of autofluorescence in the subretinal fluid area, and increasing autofluorescence at the border of the serous retinal detachment. Both patients were diagnosed with chronic central serous chorioretinopathy. Photodynamic therapy and intravitreal bevacizumab injection were administered for engorged choroidal vessels during follow-up, but neither patient showed improvement in symptoms or ophthalmologic findings. Based on re-evaluation by fundus photography, optical coherence tomography, fluorescein angiography, and comparison of the results of FAF with the first visit, vitelliform macular dystrophy was suspected and a definite diagnosis was made by electrooculography and genetic testing.

Conclusion

In patients with continuous serous retinal detachment without response to photodynamic therapy or intravitreal bevacizumab injection, careful fundus exam and FAF can be used to diagnose atypical vitelliform macular dystrophy.

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The pre-publication history for this paper can be accessed here:http://www.biomedcentral.com/1471-2415/12/25/prepub

Title: Atypical vitelliform macular dystrophy misdiagnosed as chronic central serous chorioretinopathy: case reports
Authors: Young Seob Lee
Eung-Suk Kim
Moosang Kim
Young-Gyun Kim
Hyung-Woo Kwak
Seung-Young Yu
Publication date: 01-12-2012
Publisher: BioMed Central
Published in: BMC Ophthalmology / Issue 1/2012
Electronic ISSN: 1471-2415
DOI: https://doi.org/10.1186/1471-2415-12-25

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Atypical vitelliform macular dystrophy misdiagnosed as chronic central serous chorioretinopathy: case reports

Abstract

Background

Case presentation

Conclusion

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Abstract

Background

Case presentation

Conclusion

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