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Journal of Interventional Cardiac Electrophysiology

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Open Access 01-04-2021 | Atrial Fibrillation

Real-world safety of catheter ablation for atrial fibrillation with contact force or cryoballoon ablation

Authors: Andrea Natale, Sanghamitra Mohanty, Laura Goldstein, Tara Gomez, Tina D. Hunter

Published in: Journal of Interventional Cardiac Electrophysiology | Issue 3/2021

Abstract

Purpose

Real-world data can help medical administrators, physicians, and payers make evidence-based decisions regarding treatment choices. The objective of this study was to compare real-world safety outcomes with the latest catheter technologies used for the treatment of atrial fibrillation (AF).

Methods

The Vizient Health Systems database, a large US hospital database, was used to compare acute complications in AF ablation with the contact force sensing THERMOCOOL SMARTTOUCH® Catheter or the THERMOCOOL SMARTTOUCH® SF Catheter (ST) versus the second-generation Arctic Front Advance™ Cryoablation Catheter (CB2) between September 2015 and June 2017. The primary outcome was a composite safety endpoint of acute ablation-related complications defined via ICD-10 diagnosis and procedure codes, including tamponade and other pericardial events, respiratory complications, stroke, cerebral or pre-cerebral occlusion/stenosis without infarction, vascular access complications, hemorrhage, phrenic nerve injury, myocardial infarction, and pulmonary embolism.

Results

In total, 1473 ablations met all inclusion criteria (407 ST, 1066 CB2). Ablations for paroxysmal AF (PAF) had a lower complication rate than ablations for persistent AF (PsAF) (6.1% vs. 7.3%), as did ablations with ST compared with CB2 within each AF type (PAF 6.0% vs. 6.1%, PsAF 6.3% vs. 7.8%). Neither ablation catheter nor AF type was statistically significant after controlling for site volume, patient age, and comorbid conditions (ST vs. CB2: OR 0.86, p = 0.5544; PsAF vs. PAF: OR 1.08, p = 0.7376).

Conclusion

Acute ablation-related complication rates were low and were not significantly associated with catheter technology. Increased risk of complication was attributable to low-volume sites and baseline patient characteristics.

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Title: Real-world safety of catheter ablation for atrial fibrillation with contact force or cryoballoon ablation
Authors: Andrea Natale
Sanghamitra Mohanty
Laura Goldstein
Tara Gomez
Tina D. Hunter
Publication date: 01-04-2021
Publisher: Springer US
Keyword: Atrial Fibrillation
Published in: Journal of Interventional Cardiac Electrophysiology / Issue 3/2021
Print ISSN: 1383-875X
Electronic ISSN: 1572-8595
DOI: https://doi.org/10.1007/s10840-020-00734-w

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Real-world safety of catheter ablation for atrial fibrillation with contact force or cryoballoon ablation

Abstract

Purpose

Methods

Results

Conclusion

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Abstract

Purpose

Methods

Results

Conclusion

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