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01-05-2014 | Original Article

Atrial fibrillation after esophageal cancer surgery: an analysis of 207 consecutive patients

Authors: Toshiyasu Ojima, Makoto Iwahashi, Mikihito Nakamori, Masaki Nakamura, Masahiro Katsuda, Takeshi Iida, Keiji Hayata, Hiroki Yamaue

Published in: Surgery Today | Issue 5/2014

Abstract

Purpose

The aim of this study was to identify perioperative risk factors that are associated with postoperative atrial fibrillation (AF) and the outcomes of different pharmacological interventions in esophageal cancer patients who underwent transthoracic esophagectomy.

Methods

This study included 207 patients who underwent a transthoracic esophagectomy for esophageal cancer resection by a single surgeon from January 1, 2004, through December 31, 2010.

Results

Postoperative AF occurred in 19 patients (9.2 %), all of whom received antiarrhythmic drug therapy at the early stage. Antiarrhythmic treatment was effective in 12 cases (63.2 %). In this study, landiolol hydrochloride, an ultrashort-acting β₁-selective β-blocker, was the first-line therapy for postoperative AF. A multivariate logistic regression analysis showed that postoperative AF was significantly associated with the use of an ileo-colon for reconstruction after esophagectomy (P = 0.0023, odds ratios [OR] = 13.6) and with the presence of tachycardia with a heart rate of >100 bpm on postoperative day (POD) 1 (P = 0.0004, OR = 18.4).

Conclusions

Postoperative AF is associated with the use of a colon conduit for reconstruction after esophagectomy and with tachycardia with a heart rate >100 bpm on POD 1. Identifying patients at high risk for postoperative AF will allow for more direct application of pharmacological methods of prophylaxis.

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Title: Atrial fibrillation after esophageal cancer surgery: an analysis of 207 consecutive patients
Authors: Toshiyasu Ojima
Makoto Iwahashi
Mikihito Nakamori
Masaki Nakamura
Masahiro Katsuda
Takeshi Iida
Keiji Hayata
Hiroki Yamaue
Publication date: 01-05-2014
Publisher: Springer Japan
Published in: Surgery Today / Issue 5/2014
Print ISSN: 0941-1291
Electronic ISSN: 1436-2813
DOI: https://doi.org/10.1007/s00595-013-0616-3

At a glance: The STEP trials

Springer Medicine

Atrial fibrillation after esophageal cancer surgery: an analysis of 207 consecutive patients

Abstract

Purpose

Methods

Results

Conclusions

At a glance: The STEP trials

Springer Medicine

Abstract

Purpose

Methods

Results

Conclusions

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