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Journal of Medical Case Reports

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Open Access 01-12-2013 | Case report

Atopic dermatitis, short stature, skeletal malformations, hyperimmunoglobulin E syndrome, hypereosinophilia and recurrent infections: a case report

Authors: Salvatore Leonardi, Martina Filippelli, Valentina Costanzo, Novella Rotolo, Mario La Rosa

Published in: Journal of Medical Case Reports | Issue 1/2013

Abstract

Introduction

We report an interesting clinical case which could represent a new syndrome never described previously in the literature.

Case presentation

A 15-year-old Caucasian boy presented to our institution with recurrent respiratory infections, severe atopic dermatitis, short stature and skeletal malformations. Laboratory tests showed a high level of immunoglobulin E, hypereosinophilia with a normal white blood cell count and a low level of somatomedin C. The patient had had atopic dermatitis resistant to treatment since the age of 6 months. His height did not increase despite receiving cyclic therapy with recombinant growth hormone.

Conclusion

We hypothesized the presence of several diseases not confirmed by any genetic tests. Our patient could have an unknown disease. Further research is needed to identify this possible new syndrome.

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Title: Atopic dermatitis, short stature, skeletal malformations, hyperimmunoglobulin E syndrome, hypereosinophilia and recurrent infections: a case report
Authors: Salvatore Leonardi
Martina Filippelli
Valentina Costanzo
Novella Rotolo
Mario La Rosa
Publication date: 01-12-2013
Publisher: BioMed Central
Published in: Journal of Medical Case Reports / Issue 1/2013
Electronic ISSN: 1752-1947
DOI: https://doi.org/10.1186/1752-1947-7-253

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Atopic dermatitis, short stature, skeletal malformations, hyperimmunoglobulin E syndrome, hypereosinophilia and recurrent infections: a case report

Abstract

Introduction

Case presentation

Conclusion

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Abstract

Introduction

Case presentation

Conclusion

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