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01-12-2005

Asystole during Outbursts of Laughing in a Child with Angelman Syndrome

Authors: W.Y. Vanagt, C.F. Pulles-Heintzberger, K. Vernooy, R.N. Cornelussen, T. Delhaas

Published in: Pediatric Cardiology | Issue 6/2005

Abstract

A girl with Angelman syndrome had recurrent episodes of ventricular asystole and syncope caused by severe vagal hypertonia during outbursts of laughing. After intravenous administration of atropine, laughing no longer induced asystole or syncope. The vast majority of patients with Angelman syndrome have seizures. Since hypoxia associated with asystole can provoke convulsions, we suggest electrocardiographic evaluation of Angelman patients with symptomatic bradycardia, loss of consciousness, or convulsions related to laughing.

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Title: Asystole during Outbursts of Laughing in a Child with Angelman Syndrome
Authors: W.Y. Vanagt
C.F. Pulles-Heintzberger
K. Vernooy
R.N. Cornelussen
T. Delhaas
Publication date: 01-12-2005
Publisher: Springer-Verlag
Published in: Pediatric Cardiology / Issue 6/2005
Print ISSN: 0172-0643
Electronic ISSN: 1432-1971
DOI: https://doi.org/10.1007/s00246-005-0985-5

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Asystole during Outbursts of Laughing in a Child with Angelman Syndrome

Abstract

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Abstract

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